This volume chronicles the 16th Annual Conference on System Engineering Research (CSER) held on May 8-9, 2018 at the University of Virginia, Charlottesville, Virginia, USA. The CSER offers researchers in academia, industry, and government a common forum to present, discuss, and influence systems engineering research. It provides access to forward‐looking research from across the globe, by renowned academicians as well as perspectives from senior industry and government representatives. Co‐...