This book is about the p53 gene, one of the most frequently mutated or deleted genes in human cancers. The frequent occurrence of inactivated p53 implicates this gene product in the genesis of many human cancers. The p53 gene can suppress the growth of cancer cells and the transformation process by oncogenes. The p53 protein is a transcription factor that can repress or activate promoters containing one of three p53 DNA-binding motifs. The activity of p53 is regulated by phosphorylation an...

Il demone di Maxwell è un mistero, la cui soluzione è accessibile solo rompendo le pareti della logica, ma è anche un visionario romanzo-mondo che racconta il potere della scrittura di costruire ponti tra le persone. Il protagonista di questa storia, Thomas Quinn, è uno scrittore fallito, figlio di un affermato romanziere con il quale ha avuto per tutta la vita un rapporto di rancore e distanza. I suoi libri non hanno mai trovato fortuna e a lui è rimasta solo l'invidia per Andrew Black, i...

‘Ingeniously plotted and compulsively well-paced’ Sunday Times‘A cracking detective story that seems to be investigating its own existence’ Jeff Noon'Are you there, Tom?'I stood in the doorway, staring at the phone.My father had been dead for almost seven years.When Thomas Quinn receives a seemingly impossible voice message, he can’t help but wonder if Andrew Black – a legendary, reclusive mystery writer and his fathe...

This audiobook is narrated by a digital voice.The zodiac signs in great details will give you an interesting journey through all the signs. You will learn about the characteristic of your sign, which will help you get a better understanding of yourself and other people around you.You will find out what the special mission and talent of each sign are and how you can make use of it.Combining the elements, fire, earth, air and water. Find out how compa...

As you read through the chapters, you’ll find reflection prompts, practical exercises, and daily practices that make emotional mastery part of your lifestyle. You won’t just read about change—you’ll experience it.If you’ve ever wondered how to achieve emotional balance, inner strength, and mental well-being, this book is for you. Remember, emotions will always be a part of your life. The choice is whether you allow them to control you or you learn to rise above and...

This audiobook is narrated by a digital voice.AI Guide for BeginnersDiscover the world of Artificial Intelligence in the most accessible way possible. This beginner-friendly guide is designed for curious minds with no technical background who want to understand how AI works, why it matters, and how it's shaping the future.From the basics of machine learning to real-world applications like chatbots, self-driving cars, and voice assistants, this book ...

This audiobook is narrated by a digital voice."Network Marketing Made Simple" is your ultimate guide to mastering the art of network marketing and building a successful home-based business. Whether you're a beginner or an experienced entrepreneur, this guide will break down complex concepts into simple, actionable steps that you can implement right away. Learn how to create a thriving network, generate passive income, and grow your business with effective strategie...

This audiobook is narrated by a digital voice.As you read through the chapters, you’ll find reflection prompts, practical exercises, and daily practices that make emotional mastery part of your lifestyle. You won’t just read about change—you’ll experience it.If you’ve ever wondered how to achieve emotional balance, inner strength, and mental well-being, this book is for you. Remember, emotions will always be a part of your life. The choice is whether you al...

OBSERVER THRILLER OF THE MONTH SUNDAY TIMES CRIME CLUB PICK A HEARTSTOPPING, GRISLY MOORS THRILLER ABOUT A WOMAN WHO WILL STOP AT NOTHING TO GIVE HER DAUGHTER A BETTER LIFE _______ 'Fast paced and shocking' Observer A brilliant example of Northern noir' Sunday Times 'Dark, grisly and utterly compelling. Thriller writing at its finest' CAROL WYER 'A bruising story drenched in dread. . . recalls Cormac McCarthy in its drive and brutality' GABRIEL BERGMOSER 'Dark, fast-paced and thrilling' AL...

The son of a famous writer is caught in a cat-and-mouse game with his late father's protégé in this "heady postmodern thriller" ( Publishers Weekly).Thomas Quinn is having a hard time. A failed novelist, he's stuck writing short stories and audio scripts for other people's characters. His wife, Imogen, is working on a remote island halfway around the world, and talking to her over the webcam isn't the same. The bills are piling up, the dirty dishes are sta...

Covering the period from World War II through the Trump presidency, Peace, War, and Partnership: Congress and the Military since World War II unpacks the vital and dynamic relationship between Congress and the military, two entities that have worked together, at times with different purposes, to solve myriad important issues impacting the United States in both peace and war. Congress and the military have had their periods of cooperation. However, they have also had alternating pe...

Signed first editionThis autumn, life is catching up with Thomas Quinn.Five years ago, his mentor Andrew Black wrote a single, million-selling mystery novel and then disappeared. Now could it be that Quinn is being stalked by the hero of Black’s book? His girlfriend Imogen usually has the answers but she’s working on the other side of the world and talking to her on webcam just isn’t the same.Quinn finds himself in a world that might well be coming a...