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  • Genome Assembly

    Edición de Rhys A. Farrer ...
    Series series Springer Protocols
    This detailed volume examines a wide range of disciplines involving genome assembly and its uses. Covering a diversity of taxa including bacteria, archaea, viruses, animals, plants, and fungi, the book demonstrates the similarities and differences in genome assembly methods and biological differences across those groups, while also describing the latest advances in modern sequencing strategies as ... Leer más

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  • Bioinformatics and Functional Genomics

    The bestselling introduction to bioinformatics and genomics – now in its third editionWidely received in its previous editions, Bioinformatics and Functional Genomics offers the most broad-based introduction to this explosive new discipline. Now in a thoroughly updated and expanded third edition, it continues to be the go-to source for students and professionals involved in biomedical research ... Leer más

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  • Handbook of Molecular Microbial Ecology I

    Metagenomics and Complementary Approaches

    The premiere two-volume reference on revelations from studying complex microbial communities in many distinct habitatsMetagenomics is an emerging field that has changed the way microbiologists study microorganisms. It involves the genomic analysis of microorganisms by extraction and cloning of DNA from a group of microorganisms, or the direct use of the purified DNA or RNA for sequencing, which ... Leer más

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  • The Pangenome

    Diversity, Dynamics and Evolution of Genomes

    Edición de Hervé Tettelin, Duccio Medini ...
    This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications.The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species ... Leer más

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  • Advances in the Understanding of Biological Sciences Using Next Generation Sequencing (NGS) Approaches

    Series series Biomedical and Life Sciences (R0)
    Provides a global view of the recent advances in the biological sciences and the adaption of the pathogen to the host plants revealed using NGS. Molecular Omic’s is now a major driving force to learn the adaption genetics and a great challenge to the scientific community, which can be resolved through the application of the NGS technologies. The availability of complete genome sequences, the ... Leer más

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  • Drosophila

    Methods and Protocols

    Edición de Christian Dahmann ...
    Series series Springer Protocols
    This third edition expands on the previous editions by providing updated protocols and current methods that cover recent breakthroughs in Drosophila research. Chapters guide readers through FlyBase, versatile gene expression systems, analysis of microRNA function, single-cell transcriptome data and metabolism, recent applications of CRISPR for precise genome editing, transcriptional activation and ... Leer más

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  • Next Generation Sequencing Technologies and Challenges in Sequence Assembly

    Series series Biomedical and Life Sciences (R0)
    The introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics ... Leer más

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  • IMMUNO-model in Cancer

    Methods and Protocols

    Edición de Sweta Rani, Lukasz Skalniak ...
    Series series Springer Protocols
    This open access volume describes the computational and experimental models that help researchers understand the responses of the immune system in cancer and test experimental immune-oncology approaches. The chapters in this book cover methods such as profile polarization in macrophages using ELISA; immune checkpoint inhibitors; interactions of PD-1/PD-L1 and T cells; immunocompetent preclinical ... Leer más

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  • Insect Genomics

    Methods and Protocols

    Series series Springer Protocols
    This collection explores advances in genome sequencing and analysis tools for the understanding of insect genomes and hence their biology. Beginning with obtaining a high-quality genome assembly using the latest sequencing data, the book continues with the identification of genome variability including single nucleotide polymorphisms and genomic inversions, and the annotation of insect genomes ... Leer más

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  • High Throughput Gene Screening

    Methods and Protocols

    Series series Springer Protocols
    This volume explores the latest advancements in the high-throughput sequencing (HTS) technologies and its uses in our understanding of complex biological processes and human diseases. The chapters in this book are organized into five parts and cover topics such as genome based-sequencing technologies, including whole genome sequencing, targeted sequencing, and metagenomic analysis; epigenome-based ... Leer más

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  • Nanopore Sequencing

    Methods and Protocols

    Edición de Kazuharu Arakawa ...
    Series series Springer Protocols
    This volume provides comprehensive dry and wet experiments, methods, and applications on nanopore sequencing. Chapters guide readers through bioinformatic procedures, genome sequencing, analysis of repetitive regions, structural variations, rapid and on-site microbial identification, epidemiology, and transcriptome analysis. Written in the format of the highly successful Methods in Molecular ... Leer más

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  • Transposable Elements

    Methods and Protocols

    Series series Springer Protocols
    The volume presents a small selection of state-of-the-art approaches for studying transposable elements(TE). Chapters guide readers through HTS-based approaches, bioinformatic tools, methods to studyTE protein complexes, and the functional impact on the host. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of ... Leer más

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