A practical guide to network meta-analysis with examples and codeIn the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish which interventions are effective and cost-effective. Often a single study will not provide the answers and it is desirable to synthesise evidence from multiple sources, usually randomised controlled trials. This book takes an approach to evidence synthesis that is specifically intended for decision...

In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish interventions that are both effective and cost-effective. Usually a single study will not fully address these issues and it is desirable to synthesize evidence from multiple sources. This book aims to provide a practical guide to evidence synthesis for the purpose of decision making, starting with a simple single parameter model, where all studies estimate the same quantity (pairwise met...

Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials. The methodology of clinical trials has advanced greatly over the last 20 years and, arguably, nowhere greater than that of early phase studies. The need to accelerate drug development in a rapidly evolving context of targeted therapies, immunotherapy, combination treatments and complex group structures h...

Now that people are aware that data can make the difference in an election or a business model, data science as an occupation is gaining ground. But how can you get started working in a wide-ranging, interdisciplinary field that’s so clouded in hype? This insightful book, based on Columbia University’s Introduction to Data Science class, tells you what you need to know.In many of these chapter-long lectures, data scientists from companies such as Google, Microsoft, and eBay share n...

The fun and easy way to get down to business with statisticsStymied by statistics? No fear? this friendly guide offers clear, practical explanations of statistical ideas, techniques, formulas, and calculations, with lots of examples that show you how these concepts apply to your everyday life.Statistics For Dummies shows you how to interpret and critique graphs and charts, determine the odds with probability, guesstimate with confidence using confi...

An Introduction to Stochastic Modeling, Student Solutions Manual (e-only)

Translating the evidence from the bedside to populationsThis sixth edition of the best-selling Epidemiology, Evidence-based Medicine and Public Health Lecture Notes equips students and health professionals with the basic tools required to learn, practice and teach epidemiology and health prevention in a contemporary setting.The first section, 'Epidemiology', introduces the fundamental principles and scientific basis behind work to improve the healt...

Praise for the Second Edition"This book has never had a competitor. It is the only book that takes a broad approach to sampling . . . any good personal statistics library should include a copy of this book."—Technometrics"Well-written . . . an excellent book on an important subject. Highly recommended."—Choice"An ideal reference for scientific researchers and other professionals who use sampling."—Zentralbl...

Bioinformatics for Beginners: Genes, Genomes, Molecular Evolution, Databases and Analytical Tools provides a coherent and friendly treatment of bioinformatics for any student or scientist within biology who has not routinely performed bioinformatic analysis. The book discusses the relevant principles needed to understand the theoretical underpinnings of bioinformatic analysis and demonstrates, with examples, targeted analysis using freely available web-based software and publicly available...

Collecting together twenty-three self-contained articles, this volume presents the current research of a number of renowned scientists in both probability theory and statistics as well as their various applications in economics, finance, the physics of wind-blown sand, queueing systems, risk assessment, turbulence and other areas.The contributions are dedicated to and inspired by the research of Ole E. Barndorff-Nielsen who, since the early 1960s, has been and continues to be a ver...

A fundamental and straightforward guide to using and understanding statistical concepts in medical researchDesigned specifically for healthcare practitioners who need to understand basic biostatistics but do not have much time to spare, The Essentials of Biostatistics for Physicians, Nurses and Clinicians presents important statistical methods used in today's biomedical research and provides insight on their appropriate application. Rather than provide det...

This book brings the power of multivariate statistics to graduate-level practitioners, making these analytical methods accessible without lengthy mathematical derivations. Using the open source, shareware program R, Professor Zelterman demonstrates the process and outcomes for a wide array of multivariate statistical applications. Chapters cover graphical displays, linear algebra, univariate, bivariate and multivariate normal distributions, factor methods, linear regressio...