This issue of Surgical Oncology Clinics of North America focuses on Immunotherapy for Solid Malignancies and is edited by Dr. Alfred E. Chang. Articles will include: Current immunotherapy practices for melanoma; Immunotherapy for ovarian cancer; Vaccines therapies for melanoma; Vaccine therapies for breast cancer; Induced pleuripotent T cells for adoptive immunotherapy; Future research goals in immunotherapy; Oncolytic immunotherapy; Adoptive T cell therapy for solid malignancies; Checkpoi...

In a tempestuous narrative that sweeps across five continents and seven centuries, this book explains how a succession of catastrophes—from the devastating Black Death of 1350 through the coming climate crisis of 2050—has produced a relentless succession of rising empires and fading world orders.During the long centuries of Iberian and British imperial rule, the quest for new forms of energy led to the development of the colonial sugar plantation as a uniquely profitable kind of com...

This book is about basic life knowledge to equip the mind to be able to face life challenges of growth and open ones mind to see beyond their limitations. This book is dedicated to all who are up to discover themselves, seeking the wisdom of life and sworn to themselves to fulfill their dreams . The scripture says "my people are destroyed because of lack of knowledge "Hosea4:6.This book's goal is to bring the longing souls to the knowledge.This book reveals the fundamental knowledge that i...

In 2012–2013, one of the largest U.S. newspaper chains, Advance Publications, determined its main product was no longer newspapers but news, and switched from daily print publication of The Times-Picayune of New Orleans to three days a week, while upgrading its presence online (“Digital First”). More than two hundred employees, including half the newsroom, were laid off in one of the poorest U.S. cities with among the lowest literacy rates and percentages of households with Internet access...

Johannesburg was still a brash mining town, better known for the production of wealth than knowledge, and the University of the Witwatersrand a mere ten years old when, in 1932, these ten lectures were delivered under the auspices of the University Philosophical Society. They portrayed the ideas of the university’s leading academics of the day, and the programme of lectures reveals a studied effort to introduce an element of bipartisan political representation between English and Afrikaner...

A History of the German Public Pension System: Continuity amid Change provides the first comprehensive institutional history of the German public pension system from its origins in the late nineteenth century to the major reform period in the early twenty-first century. Relying on a wide range sources, including many used for the first time, this study provides a balanced account of how the pension system has coped with major challenges, such as Germany’s defeat in two world wars, inflatio...

In a tempestuous narrative that sweeps across five continents and seven centuries, this book explains how a succession of catastrophes—from the devastating Black Death of 1350 through the coming climate crisis of 2050—has produced a relentless succession of rising empires and fading world orders.During the long centuries of Iberian and British imperial rule, the quest for new forms of energy led to the development of the colonial sugar plantation as a uniquely prof...

Originally published in 1979, this study develops a model that explains the rate of adoption of an innovation in an industry - i.e the impact of technological change upon the utilization of selected materials and energy resources in the steel, alluminium and metal can industries. Each of the three industries is examined and in subsequent chapters the model is developed, applied and evaluated.

History remembers the assassins who succeeded — but what about those who almost did? The Bullet That Missed History takes readers deep into the forgotten corners of our world's past, uncovering shocking, true, and little-known assassination attempts that could have rewritten history. From tribal leaders in remote jungles of Asia to presidents, sultans, and generals across Africa and Europe, these are the plots that failed — sometimes by inches, sometimes by sheer absurdity.

In his seminal work, "The Geographical Distribution of Animals" (Vol. 1 & 2), Alfred Russel Wallace offers a meticulous examination of the factors influencing the distribution of animal species across the globe. His comprehensive analysis is grounded in biogeography and draws upon an extensive collection of field observations, emphasizing the interplay between environment, geography, and zoological distribution. Wallace'Äôs literary style is precise and informative, indicative of the Victo...

In Alfred Russel Wallace's groundbreaking work, 'The Geographical Distribution of Animals,' readers are taken on a journey through the world of zoogeography, exploring the patterns and causes of animal distribution across different continents. Wallace meticulously examines the similarities and differences in animal species found in different geographical regions, shedding light on the interconnectedness of ecosystems and the evolutionary processes that have shaped them. Written with a prec...

"The Geographical Distribution of Animals" in 2 volumes is one of the best-known works by Alfred Russel Wallace. Extending the system developed by the British zoologist Philip Sclater for birds – which divided the earth into six separate geographic regions for describing species distribution – to cover mammals, reptiles and insects as well, Wallace created the basis for the zoogeographic regions still in use today. He discussed all of the factors then known to influence the current and pas...