Providing a holistic, global approach to all aspects of PCOS, Polycystic Ovary Syndrome: Basic Science to Clinical Advances Across the Lifespan offers authoritative guidance on the diagnosis, treatment, and management of this challenging syndrome. It presents a coherent, evidence-based approach to diagnosis, as well as recommendations for clinical practice grounded in recent advances in basic sciences. Unique in the field, this practical resource provides decision-making tools for endocrin...

With the increased prevalence of subfertility (any form of reduced fertility with prolonged time of unwanted non-conception) and the number of subfertile patients turning to assisted reproductive clinics for help, Subfertility: Recent Advances for Management and Prevention is a much-needed resource for today's health care providers. Written by doctors with extensive expertise in the areas of reproductive physiology and endocrinology, it provides a description of the methods for achieving c...

Naltrexone is an opiate antagonist drug developed in the 1970s and approved by the FDA in 1984 for opiate and drug abuse treatment. When used at much lower doses in an off-label protocol referred to as low dose naltrexone (LDN), the drug has been shown to halt disease progression in Crohn's disease and certain cancers, to reduce symptoms in multiple sclerosis and autism, and to improve numerous autoimmune and neurodegenerative conditions, including Parkinson's disease and amyotrophic later...

The potential impact of work being conducted in genomics, proteomics, and metabolomics upon clinical practice for gynecologists is immense but not yet completely appreciated. This groundbreaking text from international experts examines the newest topics on the perinatal agenda and gives clinicians a real look into the future via the newest methodologies.

This issue of Endocrinology Clinics brings the reader up to date on the latest information about hormones and cancer of the breast and prostate. The first section focuses on the breast, and topics covered include the following. The role of sex steroids and their receptors in normal breast development; estrogen carcinogenesis in breast cancer; hormonal mechanisms underlying the relationship between obesity and breast cancer; postmenopausal hormone replacement therapy and the risk of breast ...

Now in its fourth edition Testosterone: Action, Deficiency, Substitution provides the most up-to-date and comprehensive source of information on testosterone and its role in human physiology and pathology. It covers biosynthesis and mechanisms of action and reviews their effects on brain and behavior, spermatogenesis, hair growth, bones, muscles, erythropoiesis, the cardiovascular system and the prostate. The therapeutic uses of testosterone preparations are carefully evaluated as well as ...

Polycystic ovary syndrome (PCOS) is the most common endocrine disturbance, affecting 10-15% of women in the UK. The definition of PCOS has been much debated, while its pathophysiology appears to be multifactorial and is still being actively researched. There is no doubt that PCOS has a significant effect on quality of life and psychological morbidity and, as many specialists are involved in its management, a multidisciplinary approach is required. The 59th RCOG Study Group brought together...

Polycystic ovary syndrome (PCOS) is the most frequent disorder affecting women of reproductive age. Recent years have shown substantial advances in our understanding of the complex genetic, biochemical, metabolic, cardiovascular, and reproductive issues associated with PCOS. This book presents a comprehensive overview of recent clinical developments in identifying the phenotypic expression of women with PCOS resulting in a completely new recognition of its phenotypic variability. Metabolic...

Menopause: Biology and Pathobiology is a comprehensive volume covering all aspects of the biology, anatomy, physiology, pathobiology, and pharmacology of menopause, as well as its diagnosis and management.The book is divided into four sections: Basic Biology, Epidemiology, Menopausal Systems Pathophysiology, and Intervention. Basic Biology covers such fundamentals as ovarian anatomy and physiology, mechanisms of steroid hormone action, chronobiological effects, and premature menopause. Epi...

The book Gamete and Embryo-fetal Origins of Adult Diseases introduces various diseases resulting from the abnormal gametogenesis and embryo development, which manifests as growth retardation, birth defects, or increased susceptibility to chronic metabolic diseases such as diabetes, cardiovascular disease and cancer in childhood and adult life, even fertility disorders and the risk of transgenerational transmission. Six common kinds of these diseases are discussed in separate chapters. The ...

Understanding the influence and interaction between physical activity and the endocrine system are of paramount importance in dealing with a multitude of health problems. In Endocrinology of Physical Activity and Sport*, renowned physicians and researchers provide a comprehensive and expanded update on the scientific, clinical and practical components of endocrinology as related to sport and exercise. The authors thoroughly review what is known about how such activity effects the ...

Nutritional Genetics is a very brief review of nutrition and genetics with a summary the published research, primarily from PubMed.Part 1 is an introduction, beginning with DNA damage and repair, nutrigenomics, nutrigenetics and epigenetics, genetic testing. It also contains sections on vitamins and nutrients and metabolism. Part 2 describes nutritional genetics lab tests.Parts 3 to 6 have sections on diseases. Part 3 includes Eyes, Ears, Respiratory, Cardiology, and Vascular...