The conditions of Crohn’s disease and ulcerative colitis are excellent examples of how the exponential growth of knowledge in biomedical science can make a remarkable impact on clinical practice and patient’s quality of life. It has led to the development of unique novel immunomodulatory treatments. These are continuously being refined to treat not only the two original conditions in the gut, but the systemic immunologic illness with its associated extraintestinal disorders. New therapies ...

This new edition is a unique combined resource for physicians and scientists addressing the needs of both groups. In addition to stimulating exchange and collaboration and shortening the path between discovery and application of new knowledge, the book helps clinicians understand new therapeutic concepts from their origins. The volume serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonosc...

Building on the success of the 14 previous editions, this remarkable reference has been extensively reorganized and expanded and now comprises almost 1,500 individual drug articles providing the most complete coverage of adverse reactions and interactions found anywhere. Each article contains detailed and authoritative information about the adverse effects of each drug, with comprehensive references to the primary literature making this a must have for any academic or medical library, phar...

Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, and brain trauma as well as meningitis and contributes to the generation of pain. We are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage through tolerance to modulation and repair.This book discusses some of the more common neuro-inflammatory diseases. Topics covered include multiple sclerosis, optic neu...

Hypertensive disorders remain one the major causes of maternal and fetal morbidity and death. It is also a leading cause of preterm birth now known to be a risk factor in remote cardiovascular disease. Despite this, the hypertensive disorders remain marginally studied, and their management is commonly controversial. Chesley’s Hypertensive Disorders in Pregnancy remains one of the beacons to guide this field, recognized for its uniqueness and utility. The Third Edition continues th...

The new edition of a concise yet thorough illustrated review of the diagnosis and treatment of many forms of psoriasis now includes the many new therapies available and in development, as well as more material on psoriasis as a systemic disease and on comorbidities. This will be of interest to all dermatologists in training and practice, as well as primary care physicians.

This book provides a thorough and up-to-date discussion of key issues in the supportive care of children with cancer. A variety of frequently encountered situations is covered, including infections, metabolic, cardiopulmonary and neurologic emergencies, tumor lysis syndrome, pain, emesis, mucositis, thrombotic disorders, nutritional problems, hyperleukocytosis and acute abdomen. Throughout the emphasis is firmly on evidenced-based guidance developed from the relevant literature. Informatio...

Radiation Therapy Treatment Effects is a practical guide to common and uncommon toxicities which occur related to radiation therapy. Organized by anatomic region, from CNS to skin and extremities, it concisely and comprehensively reviews the symptoms, timing, preventative measures, and treatment of acute, delayed, and chronic radiation toxicities and provides evidence-based recommendations for management of both early and late effects. Other important chapters consist of topics su...

Sjögren’s Syndrome: Diagnosis and Therapeutics provides a thorough, multisystemic overview of the clinical manifestations of Sjögren’s Syndrome. It contains chapters pertinent across the range of medical specialties that may encounter Sjögren’s Syndrome cases. Chapters are specialty-specific, for easy reference by the relevant medical specialist. In addition to being a diagnostic guide, Sjögren’s Syndrome: Diagnosis and Therapeutics includes a section on prognosis and outcomes of Sjögren’s...

With a focus on improving diagnosis and treatment, Drug Allergy Testing is your new go-to resource for understanding various drug allergies and testing methods, the epidemiology of and economic impact of drug allergies, and new drug and allergy developments. - Features a wealth of up-to-date information for allergists, immunologists, and primary care physicians who diagnose and treat patients with drug allergies and hypersensitivity. - Covers the basics of drug allergy evaluation and manag...

Developed by the Blood and Marrow Transplant team at Oregon Health & Science University Knight Cancer Institute, this pocket guide provides management guidelines for hematopoietic stem cell transplant patients from the moment of their initial consultation throughout the transplant process. It includes indications for transplant, essential details for patient/donor evaluation, recommendations for management of complications during and after transplant, and guidelines for long-term follow up...

Despite significant improvement in the management of patients with chronic kidney disease, the morbidity and mortality remain high. However more is now understood about the hormonal influence on bone and vascular structures, and there have been major advances in the field of bone and mineral metabolism. This has lead to the development of new treatment strategies and agents. This new second edition reflects the most current thinking and understanding in this fascinating field, as presented...