Summarises current research on optimising CA system practices and their ecological, economic and social benefits.Elaborates on how CA systems make efficient use of production inputs such as water, nutrients, energy and addresses challenges in such areas as weed, insect pest and disease management.Reviews the central issues of improvement in yield, profitability and ecosystem services as well as climate change adaptability and mitigation in CA systems.

A practical guide to the design, conduction, analysis and reporting of clinical trials with anticancer drugs.

Cities play a major role in tackling the COVID-19 pandemic as many measures are adopted at the scale of cities and involve adjustments to the way urban areas operate.Drawing from case studies across the globe, this book explores how the pandemic and the policies it has prompted have caused changes in the ways cities function. The contributors examine the advancing social inequality brought on by the pandemic and suggest policies intended to contain contagion whilst managing the eco...

If people are to survive in these ever harsher conditions, their crops need to withstand drought, high temperatures and poor soils.Cactus crops are gaining increasing interest across the globe, in particular cactus pear (Opuntia ficus-indica), because of its unique characteristics which provide resilience to the above mentioned harsh conditions. Cactus pear is able to grow on land where no other crops are able to grow; it can be used to restore degraded land and in many countries, ...

This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered ...

This open access book explores the agenda of education policies in the 21st century. In the first part of the book, education is handled from a historical and political framework, and the effects of the change of states and policies on education are examined. In the second part, the effects of changes in the economy on education policies and economies’ demands from educational institutions are examined. In the last section, current policies in the international education sector, which is g...

An electronic version of this book is available Open Access at www.tandfebooks.com. It has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 3.0 license.One of the major challenges of urban development has been reconciling the way cities develop with the mounting evidence of resource depletion and the negative environmental impacts of predominantly urban-based modes of production and consumption. This book aims to re-politicise the relationship ...

The promise of competitiveness and economic growth in so-called smart cities is widely advertised in Europe and the US. The promise is focussed on global talent and knowledge economies and not on learning and innovation. But to really achieve smart cities – that is to create the conditions of continuous learning and innovation – this book argues that there is a need to understand what is below the surface and to examine the mechanisms which affect the way cities learn and then connect toge...

Nitrogen (N) is potentially one of the most complex elements on the Earth. It is necessary for all biological activity, but creates negative impacts on water and air quality. There is a balancing act between deficiency and surplus and the forms of N available further complicate our understanding of the dynamics. Biological fixation provides some plants with N supply while others are totally dependent upon N being available in the soil profile for the roots to extract. Nevertheless, the dem...

Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the t...

This open access book bridges the disciplinary boundaries within the social sciences to explore the role of social institutions in shaping geographical contexts, and in creating new knowledge. It includes theorizations as well as original empirical case studies on the emergence, maintenance and change of institutions as well as on their constraining and enabling effects on innovation, entrepreneurship, art and cultural heritage, often at regional scales across Europe and North America. Roo...

Clinical Trials: Study Design, Endpoints and Biomarkers, Drug Safety, and FDA and ICH Guidelines is a practical guidebook for those engaged in clinical trial design. This book details the organizations and content of clinical trials, including trial design, safety, endpoints, subgroups, HRQoL, consent forms and package inserts. It provides extensive information on both US and international regulatory guidelines and features concrete examples of study design from the medical literature. Thi...