The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume ...

The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume ...

Little daily hassles can add up to big, big stress.Whether you're stuck in traffic, hauling your kids out the front door in the morning, dealing with a demanding boss, or worrying about money, it's easy to become overwhelmed. Stress is a normal part of daily life; but over time, chronic stress can take its toll on both your mental and physical health, leading to everything from anxiety and depression to weight gain and disease. So how can you move past the little hassles t...

An expert explores the biological and emotional nature of pain: why it hurts and why some pain is good and some pain is bad.If you touch something hot, it hurts. You snatch your hand away from the hot thing immediately. Obviously. But what is really happening, biologically—and emotionally? In Understanding Pain, Fernando Cervero explores the mechanisms and the meaning of pain. When you touch something hot, your brain triggers a reflex action that causes yo...

Delirium, stupor and coma are common clinical states that confront clinicians in almost every medical specialty. With appropriate diagnosis and treatment, coma can often be treated successfully. Conversely, delay in diagnosis and treatment may be lethal. This monograph provides an update on the clinical approach that was laid out in the previous 3 editions. It describes an approach for the physician at the bedside to diagnose and treat alterations of consciousness, based on pathophysiologi...

Useful information and real hope for patients and families whose lives have been altered by traumatic brain injury.A traumatic brain injury is a life-changing event, affecting an individual’s lifestyle, ability to work, relationships—even personality. Whatever caused it—car crash, work accident, sports injury, domestic violence, combat—a severe blow to the head results in acute and, often, lasting symptoms. People with brain injury benefit from understanding, patie...

The Handbook of Clinical Neurology Vol 101: Muscular Dystrophies discusses the pathogenesis and treatment prospects for muscular dystrophies. It summarizes the advances in molecular and cell biology, biochemistry, and other biological sciences, with an emphasis on their application to this group of muscle disorders and to their clinical implications. Starting with an overview of muscular dystrophies, the book's 16 chapters discuss dystrophinopathies; sarcoglycanopathies; congenital muscula...

Human beings evolved in the company of others and flourish in proportion to their positive social ties. To understand the human brain, we must situate its biology in the wider context of society. To understand society, we must also consider how the brains and minds of individuals shape interactions with other human beings. Social Neuroscience offers a comprehensive new framework for studying the brain, human development, and human behavior.In this book, leading researchers...

The role of free radicals and oxidative stress in neurological disorders has only recently been recognized, leaving clinical neurologists to seek in vain for information on the subject even in major textbooks. What published information there is may consist of brief reminders of the possible association of superoxidase dismutase with familial amyotrophic lateral sclerosis and nitrous oxide with migraine. With luck they may also find information on the purported role of free radicals in the...

Motion processing is an essential piece of the complex brain machinery that allows us to reconstruct the 3D layout of objects in the environment, to break camouflage, to perform scene segmentation, to estimate the ego movement, and to control our action. Although motion perception and its neural basis have been a topic of intensive research and modeling the last two decades, recent experimental evidences have stressed the dynamical aspects of motion integration and segmentation. This book ...

Loudness is the primary psychological correlate of intensity. When the intensity of a sound increases, loudness increases. However, there exists no simple one-to-one correspondence between loudness and intensity; loudness can be changed by modifying the frequency or the duration of the sound, or by adding background sounds. Loudness also changes with the listener’s cognitive state. Loudness provides a basic reference for graduate students, consultants, clinicians,...

The development of more effective treatments for neuropsychiatric disorders requires scientific progress on a broad front. Animal models have a vital role to play in advancing the field. When deployed in conjunction with detailed study of these diseases in man they bring the power to make controlled experimental interventions which allow the functional consequences of genetic variations and polymorphisms to be understood in terms of their cellular, systems and behavioural effects. Further,...