This book offers a description of current and recently developed laboratory assays in the field of haemostasis and thrombosis. It is the result of a unique cooperation between experts from more than 60 institutes in 12 European countries, brought together by the ECA T (European Concerted Action on Thrombosis and Disabilities) under the auspices of the Commission of the European Communities in Brussels, Belgium. The ECAT, which was initiated in 1981, designed and performed three prospective...

The first edition of this manual appeared in 1992 and was entitled ECAT Assay Procedures. It was the result of a unique cooperation between experts brought together by the European Concerted Action on Thrombosis and Disabilities (ECAT). The Concerted Action was at that time under the auspices of the Commission of the European Union. The second edition, like the first edition, deals with diagnostic tests within the field of thrombosis. However, the second edition has a broader scope because...

Lectures on scientific data, educational lectures, and the various other forms of oral presentation are the basis for every medical meeting. Physicians are not professionally trained in giving lectures. This becomes very obvious when one visits a medical meeting. Often the message of the presentation is lost because of poor preparation, slides that fail to communicate effectively, and a generally unconvincing performance by the lecturer. To give a high-quality lecture that will be remember...

The Human Biome is a complex and essential biological system within the human body. The adult human harbors some 100 trillion bacteria in his gut alone. Balance of this system is essential to good health. This issue of Clinics in Laboratory Medicine focuses on treatments to realign this balance as well as advances in understanding the system in general. Topics include: Changes in microbiome in GERD; The relationship of microbiome, inflammation, and colon cancer; Gut microbiome and host gen...

This succinct resource provides an ideal balance of the biology and practical therapeutic strategies for classic and non-classic BCR-ABL-negative myeloproliferative neoplasms. Utilizing current World Health Organization nomenclature, classification, and diagnostic criteria, international experts have assembled to convey the most up-to-date knowledge in this rapidly evolving field. The opening chapters cover the diagnosis and classification, genetics, cytogenetic findings, and prognostic fa...

Cytokines are cellular growth factors which also provide communication between cells and their milieu. This clearly is an exciting area in modern medicine that will have significant impact on various facets of transfusion. Erythropoietin therapy stimulates red cell production while thrombopoietin seems to positively affect megakaryopoiesis and can be an added armamentarium for the thrombocytopenic patient.Using haematnopoietic growth factors, stem cells could be mobilized early to t...

This textbook is a practical guide to the use of small animal imaging in preclinical research that will assist in the choice of imaging modality and contrast agent and in study design, experimental setup, and data evaluation. All established imaging modalities are discussed in detail, with the assistance of numerous informative illustrations. While the focus of the new edition remains on practical basics, it has been updated to encompass a variety of emerging imaging modalities, methods, a...

An essential companion for both the aspiring and practising electrophysiologist, The EHRA Book of Pacemaker, ICD and CRT Troubleshooting assists device specialists in tackling both common and unusual situations that that they may encounter during daily practice. Taking a case-based approach, it examines pacemakers, implantable cardioverter defibrillators and cardiac resynchronisation therapy. Much more than just a technical manual of device algorithms, the cases help readers to co...

The last 10 years has seen explosive expansion of the number of centres performing cardiov- cular magnetic resonance (CMR) imaging. The majority of this expansion has been in the ? eld of adult ischaemic imaging, but congenital heart disease remains one of the main indications for CMR. Importantly, the greatly improved survival of patients with congenital heart disease gives us a burgeoning adult population living with the sequelae of the disease (grown-up c- genital heart disease – GUCH)....

I would like to express my great appreciation to the editors of this volume, Prof. A. De Schepper and Dr. F. Vanhoenacker, for all their efforts and their enthusiastic commitment to this book. I am very grateful to them for managing to involve so many leading experts, resulting in a much -needed high -quality and absolutely up-to-date text book on the spleen, an organ which has not always received the attention it deserves from radiologists. As series editor, I am particularly grateful to ...

Magnetic resonance angiography (MRA) continues to undergo exciting technological advances that are rapidly being translated into clinical practice. It also has evident advantages over other imaging modalities, including CT angiography and ultrasonography. With the aid of numerous high-quality illustrations, this book reviews the current role of MRA of the body. It is divided into three sections. The first section is devoted to issues relating to image acquisition technique and sequences, w...

This text is a review of molecular immunohematology (MI). It draws from analyses and case studies around the world and details many techniques used in many labs. It is aimed at anyone interested in how MI is changing blood bank and transfusion medicine.