Genetic Diagnosis of Endocrine Disorders, Second Edition provides users with a comprehensive reference that is organized by endocrine grouping (i.e., thyroid, pancreas, parathyroid, pituitary, adrenal, and reproductive and bone), discussing the genetic and molecular basis for the diagnosis of various disorders. The book emphasizes the practical nature of diagnosing a disease, including which tests should be done for the diagnosis of diabetes mellitus in adults and children, which genes sho...

Since the beginning of the current century, endocrine disease diagnosis and treatment have moved beyond the standard hormone measurements. While, indeed elevated thyroid hormone levels or low insulin levels signal a specific endocrine disease, correct diagnosis (and therefore correct treatment) depends on an understanding of the molecular basis for the disease. This book presents the "bench to bedside" approach of our understanding of the genetic basis for endocrine disease. It is organize...

This book identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluations of treatments. The book is aimed at all students of bone biology and genetics, and with this in mind, it includes general introductory chapters on genetics and bone biology and more specific disease-orientated chapters, which comprehensively summarize the clinical, genetic, molecular genetic, animal model, fun...

This is a comprehensive book addressing steroid disorders from hormonal, genetic, psychological, and surgical perspectives. It is meant to educate adult and pediatric endocrinologists, clinical geneticists, genetic counselors, reproductive endocrinologists, neonatologists, urologists, and psychoendocrinologists. It will assist these specialists in the diagnosis and treatment of steroid disorders. The book is written for postgraduate and faculty-level physicians. The content consists of ste...

Short, sassy, and bold, Mean Genes uses a Darwinian lens to examine the issues that most deeply affect our lives: body image, money, addiction, violence, and the endless search for happiness, love, and fidelity. But Burnham and Phelan don't simply describe the connections between our genes and our behavior; they also outline steps that we can take to tame our primal instincts and so improve the quality of our lives. Why do we want (and do) so many things that are bad for us? We vo...

A preeminent geneticist, winner of the 2022 Nobel Prize in medicine, hunts the Neanderthal and Denisovan genomes to answer the biggest question of them all: how did our ancestors become human?Neanderthal Man tells the riveting personal and scientific story of the quest to use ancient DNA to unlock the secrets of human evolution. Beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in the sequencing of the Neanderthal genom...

In recent years knowledge of our genetic code has changed our understanding of life on Earth. New genetic technologies are transforming the way we live and promise treatments for otherwise incurable diseases. But these advances are also generating controversy, particularly surrounding issues such as cloning and designer babies.In 50 Genetics Ideas, Mark Henderson distils the central ideas of genetics in a series of clear and concise essays. Beginning with the theory of evolution, an...

All of us have lurking in our DNA a most remarkable gene, which has a crucial job – it protects us from cancer. Known simply as p53, this gene constantly scans our cells to ensure that they grow and divide without mishap, as part of the routine maintenance of our bodies. If a cell makes a mistake in copying its DNA during the process of division, p53 stops it in its tracks, summoning a repair team before allowing the cell to carry on dividing. If the mistake is irreparable and the rogue ce...

Steve Jones’s highly acclaimed, double prize-winning, bestselling first book is now fully revised to cover all the new genetic breakthroughs from GM food to Dolly the sheep. ’An essential sightseer’s guide to our own genetic terrain.’ Peter Tallack, Sunday Telegraph’Superb and stimulating…an exhilarating trip around the double spiral of DNA, a rush of gravity-defying concepts and wild swerves of the scientific imagination.’ J.G. Ballard, Daily Telegraph’Not so much divinati...

Genetics is the newest of all sciences - nothing useful was known about inheritance until just over a century ago. Now genetics is exploding, and before long we will have the complete code, written in three thousand million letters of DNA, of what makes a human being.Introducing Genetics takes us from the early work of Mendel to the discovery of DNA, the human gene map and the treatment of inborn disease. No one can afford to be ignorant of genetics. This b...

"A lucid, thought-provoking account of the case for 'nature' as a determinant of personality."—Peter D. Kramer, Author of Listening to Prozac and Should You Leave?Nowhere is the nature-nuture controversy being more arduously tested than in the labs of world-renowned molecular scientist Dean Hamer, whose cutting-edge research has indisputably linked specific genes to behavioral traits, such as anxiety, thrill-seeking, and homosexuality. The culmination of th...

Conceptual Breakthroughs in Evolutionary Genetics is a pithy, lively book occupying a special niche—the conceptual history of evolutionary genetics— not inhabited by any other available treatment. Written by a world-leading authority in evolutionary genetics, this work encapsulates and ranks 70 of the most significant paradigm shifts in evolutionary biology and genetics during the century-and-a-half since Darwin and Mendel. The science of evolutionary genetics is central to all of biology,...