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  • Basics of Bioinformatics

    Lecture Notes of the Graduate Summer School on Bioinformatics of China

    Collection series Computer Science (R0)
    This book outlines 11 courses and 15 research topics in bioinformatics, based on curriculums and talks in a graduate summer school on bioinformatics that was held in Tsinghua University. The courses include: Basics for Bioinformatics, Basic Statistics for Bioinformatics, Topics in Computational Genomics, Statistical Methods in Bioinformatics, Algorithms in Computational Biology, Multivariate ... En savoir plus

    $107.09 USD

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  • Meta-Analysis with R

    Collection series Mathematics and Statistics (R0)
    This book provides a comprehensive introduction to performing meta-analysis using the statistical software R. It is intended for quantitative researchers and students in the medical and social sciences who wish to learn how to perform meta-analysis with R. As such, the book introduces the key concepts and models used in meta-analysis. It also includes chapters on the following advanced topics: ... En savoir plus

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  • Applied Multivariate Statistics with R

    Collection series Mathematics and Statistics (R0)
    This book brings the power of multivariate statistics to graduate-level practitioners, making these analytical methods accessible without lengthy mathematical derivations. Using the open source, shareware program R, Professor Zelterman demonstrates the process and outcomes for a wide array of multivariate statistical applications. Chapters cover graphical displays, linear algebra, univariate, ... En savoir plus

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  • Phenotypes and Genotypes

    The Search for Influential Genes

    Collection series Computer Science (R0)
    This timely text presents a comprehensive guide to genetic association, a new and rapidly expanding field that aims to elucidate how our genetic code (genotypes) influences the traits we possess (phenotypes). The book provides a detailed review of methods of gene mapping used in association with experimental crosses, as well as genome-wide association studies. Emphasis is placed on model selection ... En savoir plus

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  • Next Generation Sequencing Technologies and Challenges in Sequence Assembly

    Collection series Biomedical and Life Sciences (R0)
    The introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics ... En savoir plus

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  • Discriminative Pattern Discovery on Biological Networks

    Collection series Computer Science (R0)
    This work provides a review of biological networks as a model for analysis, presenting and discussing a number of illuminating analyses. Biological networks are an effective model for providing insights about biological mechanisms. Networks with different characteristics are employed for representing different scenarios. This powerful model allows analysts to perform many kinds of analyses which ... En savoir plus

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  • Statistical Modelling in Biostatistics and Bioinformatics

    Selected Papers

    Modifié par Gilbert MacKenzie, Defen Peng ...
    Collection series Mathematics and Statistics (R0)
    This book presents selected papers on statistical model development related mainly to the fields of Biostatistics and Bioinformatics. The coverage of the material falls squarely into the following categories: (a) Survival analysis and multivariate survival analysis, (b) Time series and longitudinal data analysis, (c) Statistical model development and (d) Applied statistical modelling. Innovations ... En savoir plus

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  • Cancer Mortality and Morbidity Patterns in the U.S. Population

    An Interdisciplinary Approach

    Collection series Mathematics and Statistics (R0)
    The purpose of this book is to examine the etiology of cancer in large human populations using mathematical models developed from an inter-disciplinary perspective of the population epidemiological, biodemographic, genetic and physiological basis of the mechanisms of cancer initiation and progression. In addition an investigation of how the basic mechanism of tumor initiation relates to general ... En savoir plus

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  • Protein Homology Detection Through Alignment of Markov Random Fields

    Using MRFalign

    Collection series Computer Science (R0)
    This work covers sequence-based protein homology detection, a fundamental and challenging bioinformatics problem with a variety of real-world applications. The text first surveys a few popular homology detection methods, such as Position-Specific Scoring Matrix (PSSM) and Hidden Markov Model (HMM) based methods, and then describes a novel Markov Random Fields (MRF) based method developed by the ... En savoir plus

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  • Soft Computing for Biological Systems

    Collection series Biomedical and Life Sciences (R0)
    This book explains how the biological systems and their functions are driven by genetic information stored in the DNA, and their expression driven by different factors. The soft computing approach recognizes the different patterns in DNA sequence and try to assign the biological relevance with available information.The book also focuses on using the soft-computing approach to predict protein ... En savoir plus

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  • BetaSys

    Systems Biology of Regulated Exocytosis in Pancreatic ß-Cells

    Collection series Biomedical and Life Sciences (R0)
    BetaSys uses the example of regulated exocytosis in pancreatic β-cells, and its relevance to diabetes, to illustrate the major concepts of systems biology, its methods and applications. ... En savoir plus

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  • Longevity Genes

    A Blueprint for Aging

    Modifié par Gil Atzmon, PhD ...
    Collection series Biomedical and Life Sciences (R0)
    The release of the complete version of the human genome sequence in 2003 has paved the way for defining gene function and genetic background for phenotypic variation in humans and allowed us to study the aging process in a new light. This new volume results from that research and focuses on the genetic and epigenetic process of aging. While the interpretation of the genome data is still in its ... En savoir plus

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