Advances in knowledge and technology have revolutionized the process of drug development, making it possible to design drugs for a given target or disease. Building on the foundation laid by the previous three editions, Smith and Williams Introduction to the Principles of Drug Design and Action, Fourth Edition includes the latest informatio

The contemporary theologian Hans Küng has asked if the "death of God," proclaimed by Nietzsche as the event of modernity, was inevitable. Did the empowering of new forms of rationality in Western culture beginning around 1500 lead necessarily to the reduction or privatization of faith? In Dialogues between Faith and Reason, John H. Smith traces a major line in the history of theology and the philosophy of religion down the "slippery slope" of secularization—from Luther and...

Focusing on the development of enzyme inhibitors as therapeutic drugs, Enzymes and Their Inhibitors: Drug Development provides a concise overview of the chemistry of major types of enzymes and their inhibitors. The opening chapters introduce readers to the structure, functions, mechanisms, and kinetics of enzymes, including their use as disease mar

Cellular proteinases and their physiological role in normal and disease states have been the subject of great interest recently. Proteinase and Peptidase Inhibition presents new reports on a wide range of cellular proteinases whose inhibitors may hold the key to the development of new drugs. It deals with enzyme classes, inhibitor types and regulatory mechanisms governing proteinase activity. Target enzymes are fully described and classified by structural similarity, rather than by pharmac...

The glitter and excitement that tourists associate with casinos is only a facade. To the gaming industry's front-line employees, its dealers, the casino is a far less glamorous environment, a workplace full of emotional tension, physical and mental demands, humor and pathos. Author H. Lee Barnes, who spent many years as a dealer in some of Las Vegas's best-known casinos, shows us this world from the point of view of the table-games dealer. Told in the voices of dozens of dealers, male and ...

My Life in Nevada Politics tells the entertaining, informative, and at times poignant story of the rise of Richard Bryan from humble beginnings in Las Vegas to the pinnacle of Nevada politics during a time of great change across the state and nation. Through his memoir, Bryan provides keen insight into the mechanics of politics, and the book serves as a must-read for anyone interested in the history of the Silver State.Born in Washington, D.C. in 1937, Bryan grew up in Las...

A little dog, who led a long rewarding life, reflects upon her previous human relationships and relates her biography from the vantage of heaven.

This book provides a comprehensive account of the cellular pathology of glandular lesions and uncommon neoplasms of the cervix and places these in a contemporary clinical context. The book features comprehensive, detailed descriptions and a consistent approach to each tumor or tumor-like condition with clear color illustrations. Cytological/histological correlation is emphasised and diagnostic pitfalls are highlighted.Cellular Pathology of Glandular Lesions and Uncommon Neoplas...

The second original anthology in the Fiction River line, How to Save the World brings together eleven of today’s brightest authors, presenting their answers to solve a pressing problem facing the human race. From the growing energy crisis to women’s rights to overpopulation to the survival of humanity in the future, the stories in this anthology examine the issues facing our planet today—and offer hope for our survival tomorrow.Fiction River: How to Save the World...

'Living to Tell the Horrid Tales: True Life Stories of Former Slaves, Historical Documents & Novels' is a profound anthology that embodies a spectrum of narratives ranging from heart-wrenching slave narratives to poignant memoirs and reflective novels. This collection encapsulates the horrific experiences and the resilient spirit of those bound by chains, alongside the connected literary pursuits that aim to expose and abolish the brutal injustices of their times. The diversity of literary...

e-artnow presents to you the greatest Christmas novels, magical Christmas tales, legends, most famous carols and the unique poetry of the giants of literature dedicated to this one and only holiday: The Gift of the Magi (O. Henry) The Holy Night (Selma Lagerlöf) A Merry Christmas & Other Christmas Stories (Louisa May Alcott) A Letter from Santa Claus (Mark Twain) Silent Night The Night After Christmas The Child Born at Bethlehem The Adoration of the Shepherds The Visit of the Wise Men As J...

"Some Artists at the Fair" is a captivating exploration of the artistic landscape during a significant exhibition. The book features the works and insights of notable artists such as W. Hamilton Gibson, Will H. Low, Francis Davis Millet, John Ames Mitchell, and Francis Hopkinson Smith. Each artist brings a unique perspective, showcasing their contributions to the art world and the cultural milieu of the time. Through vivid descriptions and engaging narratives, the book immerses readers in ...