The European Molecular Biology Open Software Suite (EMBOSS) is a high quality, well documented package of open source software tools for molecular biology. EMBOSS includes extensive and extensible C programming libraries, providing a powerful and robust toolkit for developing new bioinformatics tools from scratch. The EMBOSS Developer's Guide is the official and definitive guide to developing software under EMBOSS. It includes comprehensive reference information and guidelines, including s...

The European Molecular Biology Open Software Suite (EMBOSS) is a high quality package of open source software tools for molecular biology. It includes over 200 applications integrated with a range of popular third party software packages under a consistent and powerful command line interface. The tools are available from a wide range of graphical interfaces, including easy to use web interfaces and powerful workflow software. The EMBOSS Administrator's Guide is the official, definitive and...

The volume is based on papers presented at a workshop on the green transport agenda and its implications for Chinese cities, organised by the World Conference on Transport Research Society in September 2010. The five sections of this volume review the challenges facing urban transport internationally and in China. It considers approaches to policy formulation, the challenge of urban mobility and the development of green sustainable transportation, by reviewing best practice in objective se...

Achieving Net Zero is a wicked problem that is not just a question of applying technological innovation to existing transport patterns and behaviours. It involves all three aspects of the environmental, social and economic sustainability triangle and any attempt to significantly reduce transport’s CO2 emissions will involve major technological and behavioural changes – indeed, a fundamental rethink of existing expectations. Any approach needs also to be politically achievable, pro...

This book explores the reasons for difficulties in making cycling mainstream in many cultures, despite its claims for being one of the most sustainable forms of transport. In conditions of relatively low use, cycle users become more closely identified with their means of transport than users of other modes. Such personality-based considerations led to the need initially for the book to explore the cultural development of cycling in countries with high use and the differences in use between...

The 1970's and 1980's witnessed both substantial conceptual and practical interest in paratransit across Europe and North America, as well as widespread implementation of paratransit services and strategies. Subsequently, the trajectory of paratransit (also often referred to as flexible transport systems) has waned, to the point where it is frequently relegated to a very narrow niche (often related to special needs) in the spectrum of collective transport services. More recently, technolog...

THE LATEST BREAKTHROUGHS IN COMPUTER-AIDED DRUG DESIGN AND DELIVERYThis definitive text provides in-depth information on computer-assisted techniques for discovering, designing, and optimizing new, effective, and safe drugs. Computer-Aided Drug Design and Delivery Systems offers objective and quantitative data on the use and delivery of drugs in humans. Enabling technologies such as bioinformatics, pharmacokinetics, biosensors, robotics, and bioinstruments are thoroughly...

Life history theory seeks to explain the evolution of the major features of life cycles by analyzing the ecological factors that shape age-specific schedules of growth, reproduction, and survival and by investigating the trade-offs that constrain the evolution of these traits. Although life history theory has made enormous progress in explaining the diversity of life history strategies among species, it traditionally ignores the underlying proximate mechanisms. This novel book argues that ...

Translational Medicine: Tools and Techniques provides a standardized path from basic research to the clinic and brings together various policy and practice issues to simplify the broad interdisciplinary field. With discussions from academic and industry leaders at international institutions who have successfully implemented translational medicine techniques and tools in various settings, readers will be guided through implementation strategies relevant to their own needs and institutions. ...

Adult Stem Cells, second edition, takes a critical look at issues concerning the developmental or differentiation potential for a variety of tissue types and for specific adult stem cell types. Since the first edition appeared a decade ago, our understanding of adult stem cells, and more specifically tissue-specific adult stem cells, has advanced tremendously. And an increased interest in regenerative medicine and potential stem cell applications has driven a quest for better unde...

The mission of the Urban and Regional Policy and Its Effects series is to inform policymakers, practitioners, and scholars about the effectiveness of select policy approaches, reforms, and experiments in addressing the key social and economic problems facing today's cities, suburbs, and metropolitan areas.Volume four of the series introduces and examines thoroughly the concept of regional resilience, explaining how resilience can be promoted-or impeded-by regional character...

Bioinformatics encompasses a broad and ever-changing range of activities involved with the management and analysis of data from molecular biology experiments. Despite the diversity of activities and applications, the basic methodology and core tools needed to tackle bioinformatics problems is common to many projects. This unique book provides an invaluable introduction to three of the main tools used in the development of bioinformatics software - Perl, R and MySQL - and explains how these...