Modern brain imaging is revolutionizing the study of brain function in health and disease. However, few realize that its origins began in the nineteenth century with Dr. Angelo Mosso's pioneering experiments. A foremost Italian physiologist and scientist, Angelo Mosso studied several patients brought to him with head injuries that exposed their live brains to direct, long-term observation. He took advantage of these rare opportunities to document, for the first time, changes in cerebral bl...

"Brain Imaging Techniques" is a book chapter of the college-level textbook for the book volume in the Principles of Neuropsychopharmacology course. It is a part of the Science Textbook Series authored by Nicoladie Tam, Ph.D. that also includes the Principles of Biology course.This book is written with specific pedagogical considerations to facilitate students' learning. It applies the proven best practices to motivate students in learning. It uses multiple pedagogical methodologies ...

This book provides comprehensive and up-to-date information on the neuropsychiatric disturbances that may be experienced by patients with multiple sclerosis. The first section is designed primarily to describe the general clinical aspects of multiple sclerosis, from epidemiology to assessment tools. The role of neuroimaging and especially MRI is then explained, and treatment approaches and rehabilitation strategies are described. The core section of the volume is the second, in which the v...

What produces emotions? Why do we have emotions? How do we have emotions? Why do emotional states feel like something? What is the relation between emotion, and reward value, and subjective feelings of pleasure? How is the value of a good represented in the brain? Will neuroeconomics replace classical microeconomics? How does the brain implement decision-making? Are gene-defined rewards and emotions in the interests of the genes, and does rational multistep planning enable us to go beyond ...

Singularity Hypotheses: A Scientific and Philosophical Assessment offers authoritative, jargon-free essays and critical commentaries on accelerating technological progress and the notion of technological singularity. It focuses on conjectures about the intelligence explosion, transhumanism, and whole brain emulation. Recent years have seen a plethora of forecasts about the profound, disruptive impact that is likely to result from further progress in these areas. Many comme...

With this seventh edition, Noback’s Human Nervous System: Structure and Function continues to combine clear prose with exceptional original illustrations that provide a concise lucid depiction of the human nervous system. The book incorporates recent advances in neurobiology and molecular biology. Several chapters have been substantially revised. These include Development and Growth, Blood Circulation and Imaging, Cranial Nerves and Chemical Senses, Auditory and Vestibular Systems...

The misfolding and aggregation of specific proteins is an early and obligatory event in many of the age-related neurodegenerative diseases of humans. The initial cause of this pathogenic cascade and the means whereby disease spreads through the nervous system, remain uncertain. A recent surge of research, first instigated by pathologic similarities between prion disease and Alzheimer’s disease, increasingly implicates the conversion of disease-specific proteins into an aggregate-prone b-sh...

This work explores the power of visual and vocal channels, in conveying emotional cues exploiting realistic, dynamic and mutually related emotional vocal and facial stimuli, and aims to report on a cross cultural comparison on how people from different Western Countries perceive emotional dynamic stimuli.The authors attempt to give an answer to the following questions evaluating the subjective perception of emotional states in the single (either visual or auditory channel) and the ...

Edited by the 1991 winners of the Nobel Prize in Physiology or Medicine, this Second Edition includes new chapters covering such applications as capacitance measurements; single-cell PCR measurements; whole-cell recording from brain slices in combination with imaging techniques; atomic force microscopy of cells and membranes attached to glass pipettes; and patch clamping.

The conscious mind defines human existence. Many consider the brain as a computer, and they attempt to explain consciousness as emerging at a critical, but unspecified, threshold level of complex computation among neurons. The brain-as-computer model, however, fails to account for phenomenal experience and portrays consciousness as an impotent, after-the-fact epiphenomenon lacking causal power. And the brain-as-computer concept precludes even the remotest possibility of spirituality. As de...

A powerful collection of readily reproducible cutting-edge techniques for characterizing the ligand or substrate binding of neurotransmitter receptors and transporters. The procedures cover interdisciplinary interactions for monoamine transporters, amino acid transporters, ionotropic receptors, metabotropic glutamate receptors, GABA receptors, and other G protein-coupled receptors. By illuminating how neurons in the central nervous communicate with other, these techniques can lead to the d...