Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin ...

The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, the...

Radical Conflictaddresses conflict at interpersonal and communal, legal and rhetorical, ethnopolitical, global, and geopolitical levels. The conflicts analyzed are "radical" because in each some intense and often prolonged violence takes place. The chapters address different kinds of violence(s)—physical and gratuitous, structural and socio-economic, legal and symbolic, all with significant ill effects and injustices that spiral in all directions. All share an interest in exploring imagina...

Understanding the theories that underpin international political economy (IPE), and their practical applications, is crucial to the study of international relations, politics, development and economics. International Political Economy in the 21st Century offers students an engaging and coherent foundation to the subject. It considers traditional and alternative approaches to IPE, and in doing so elucidates key concepts, assumptions and the intellectual and historical context in wh...

A short story set in London 1970. A father takes his thirty-year-old daughter back to the town where he was born and raised. He has not been in England since 1945, when at the end of WWII he had emigrated to the U.S.A. A story of love, separation and adultery.

Wanderlust is a personal view of the joy of travelling: seeing the place ´over the hill´.Roy Smith and his wife Martha met while both were abroad. they married, and have spent the past twenty years travelling. Roy´s eagerness to see new places continues unabated.

A bittersweet story of a man remembering his late father.

Powered by Porsche - the Alternative Race Cars is a thorough and fascinating account of the racing cars that were powered by Porsche engines, but where the chassis and development of the car was carried out by others. The Porsche company in Zuffenhausen, Germany, can probably be said to be the most successful marque ever for victories in the motor racing scene. Likewise many firsts in innovation have come with the name Porsche attached. Many major racing car producers such as Elva, Lotus, ...

Adam Smith was a Scottish professor of moral philosophy. He published his classic The Wealth of Nations in 1776, the year the American Revolution began. Smith became widely known for his ideas of free markets, laissez-faire commerce, and the "invisible hand." Yet English politicians, landed gentry, and the nobility paid little attention and enacted none of Smith's suggested reforms.The American colonies, however, began their existence as an independent nation in 1781 with n...

A positive look at cancer.This short book is free. If you like it or find it useful, you could contact me, write a review, give a thumbs-up. You could also make a donation to your favorite charity. If you don´t like it, you could forget feedback, the review, and the thumb. But perhaps remember that donation.Thanks.

Sports prototype racing is about endurance, for the drivers, for the teams and for the companies involved. In this story we see the effort, the blood, the sweat and the tears, reputations won and lost, life and also death; in the case of Alpine, it had a passion and dedication for racing over a long period with stunningly beautiful, creative, slippery aerodynamic designs that allowed it to take many class wins and outright victories in championship racing, and ultimately the Le Mans 24 hou...

The last two decades saw a greater rise in wealth than during any comparable period in history. Now meet the wealth-driven people behind the dollars. The Multi-Millionaires. How Much They Made. How Each One Made It.At the beginning of 2000, there were nearly three hundred billionaires and five million millionaires living in the United States. Total household wealth had reached $37 trillion, up from just over $8 trillion when Ronald Reagan became president. he stori...