Olivia and Miguel live in the village of the Rainbow Tree. Like many young girls, Olivia would like to be a princess. Olivia wonders what it would be like to be a real princess and live in a castle. Miguel suggests that they should visit the Old Woman who lives in the village. Olivia has never met the Old Woman and does not know how to talk to old people. After school, Miguel takes Olivia to meet the Old Woman. The Old Woman tells Olivia that she was a princess and lived in a castle. The O...

The Rainbow Tree, sitting in the center of the village, has branches so large and so high that no one could see the top of the Rainbow Tree. The villagers do not know that a family of monkeys lives in the Rainbow Tree. Just like the leaves on the Rainbow Tree, each monkey is different.A very young, boy monkey named Reuben likes to ride on his mothers back, just as many baby monkeys do. His mother tells Reuben to hold on tight so that he will not fall, but Reuben wants to play with ...

Miguel is a friendly, energetic, and mischievous seven-year-old who lives in the Village of the Rainbow Tree. He has always wanted a dog. Unfortunately, his mother thinks he is too young to care for a pet.After Miguel seeks advice from an old woman in the village, she tells him it is a lot of work to feed and love a dog. After the old woman talks to his mother and receives her approval, she takes Miguel to the back of her cottage to see something. As he excitedly follows her, Migue...

The authoritative textbook on the principles and practical applications of biopharmaceutics and pharmacokineticsShargel & Yu's Applied Biopharmaceutics & Pharmacokinetics has been the standard textbook in its field for over 40 years. This eighth edition includes recent scientific developments in the field and embodies the collective contribution of experts with deep knowledge and experience in the selected subject areas. Shargel & Yu's Applied Biopharmaceu...

Generic Drug Product Development: Specialty Dosage Forms explores the issues related to providing evidence of pharmaceutical equivalence and bioequivalence for specialty drug products. It describes various scientific approaches and regulatory requirements for manufacturers who need to demonstrate the therapeutic equivalence of generic specialty dru

The assessment of bioequivalence is an important process whereby the bioavailability of a generic drug product is compared with its brand-name counterpart. Generic pharmaceutical products must be approved as therapeutic equivalents to the brand name alternative in order to be interchangeable. The demonstration of bioequivalence is an important comp

In this era of increased pharmaceutical industry competition, success for generic drug companies is dependent on their ability to manufacture therapeutic-equivalent drug products in an economical and timely manner, while also being cognizant of patent infringement and other legal and regulatory concerns.Generic Drug Product Development: Solid Oral

Due to a worldwide need for lower cost drug therapy, use of generic and multi-source drug products have been increasing. To meet international patent and trade agreements, the development and sale of these products must conform to national and international laws, and generic products must prove that they are of the same quality and are therapeutica