A human physiology expert lays out the basic facts to explain why the idea of biological sex as a binary is simply wrongBiological sex is as nuanced as gender. Many of us are biologically more typically masculine in some ways and more typically feminine in others. The constellation of traits that make up our sex identity are wide-ranging and often overlap. Height, strength, body hair, genitalia, hormonal balances—these are all part of the picture. How should we thi...

From simple reflexes to complex choreographies of movement, all animal behavior is governed by a nervous system. But what kind of government is it—a dictatorship or a democracy?Nervous systems consist of circuits of interconnected nerve cells (neurons) that transmit and receive information via electrical signals. Every moment, each neuron adds up stimulating and inhibiting inputs from many other neurons to determine whether to send an electrical signal to its recipients. Some circu...

A human physiology expert lays out the basic facts to explain why the idea of biological sex as a binary is simply wrongBiological sex is as nuanced as gender. Many of us are biologically more typically masculine in some ways and more typically feminine in others. The constellation of traits that make up our sex identity are wide-ranging and often overlap. Height, strength, body hair, genitalia, hormonal balances—these are all part of the picture. How should we thi...

The author of the bestseller The Disappearing Spoon reveals the secret inner workings of the brain through strange but true stories.Early studies of the human brain used a simple method: wait for misfortune to strike -- strokes, seizures, infectious diseases, horrendous accidents -- and see how victims coped. In many cases their survival was miraculous, if puzzling. Observers were amazed by the transformations that took place when different parts of the br...

A national bestselling author examines one of the mind's most exalted states—one that is crucially important to learning, risk-taking, social cohesiveness, and survival itself.“[Jamison is] that rare writer who can offer a kind of unified field theory of science and art.” —The Washington Post Book WorldWith the same grace and breadth of learning she brought to her studies of the mind’s pathologies, Kay Redfield Jamison examines one...

Drawing on a modern neurocognitive framework, this full-color textbook introduces the entire field of cognition through an engaging narrative. Emphasizing the common neural mechanisms that underlie all aspects of perception, learning, and reasoning, the text encourages students to recognize the interconnectivity between cognitive processes. Elements of social psychology and developmental psychology are integrated into the discussion, leading students to understand and appreciate the connec...

This book addresses the methodological issues involved in responsible innovation and provides an overview of recent applications of multidisciplinary research. Responsible innovation involves research into the ethical and societal aspects of new technologies (e.g. ICT, nanotechnology, biotechnology and brain sciences) and of changes in technological systems (e.g. energy, transport, agriculture and water). This research is highly multidisciplinary. It involves close collaboration between re...

Making a Scientific Case for Conscious Agency and Free Will makes a series of arguments that certain human behaviors are impossible to explain in the absence of free will, and that free will emerges from materialistic processes of brain function. It outlines future directions for neuroscience studies that can harness emerging technologies and tools for systems-level analysis. All humans have the sensation that they consciously will certain things to happen and that, in the absence of exter...

Hearing and communication present a variety of challenges to the nervous system. To be heard and understood, a communication signal must be transformed from a time-varying acoustic waveform to a perceptual representation to an even more abstract representation that integrates memory stores with semantic/referential information. Finally, this complex, abstract representation must be interpreted to form categorical decisions that guide behavior. Did I hear the stimulus? From where and whom d...

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biolog...

This Handbook brings together and integrates comprehensively the core approaches to fear and anxiety. Its four sections: Animal models; neural systems; pharmacology; and clinical approaches, provide a range of perspectives that interact to produce new light on these important and sometimes dysfunctional emotions. Fear and anxiety are analyzed as patterns that have evolved on the basis of their adaptive functioning in response to threat. These patterns are stringently selected, providing a ...

A powerful collection of readily reproducible cutting-edge techniques for characterizing the ligand or substrate binding of neurotransmitter receptors and transporters. The procedures cover interdisciplinary interactions for monoamine transporters, amino acid transporters, ionotropic receptors, metabotropic glutamate receptors, GABA receptors, and other G protein-coupled receptors. By illuminating how neurons in the central nervous communicate with other, these techniques can lead to the d...