Pyruvate kinase (PK) deficiency is an inherited disease that affects red blood cells and manifests as hemolytic anemia. It is a lifelong condition, with symptoms that range from mild to severe. Despite an ever-growing understanding of its pathophysiology, etiology, and epidemiology, and an active research program, PK deficiency remains unfamiliar to many medical practitioners. PK deficiency is clinically heterogeneous, so healthcare professionals need to consider the possibility of this di...

Vous ne connaissez peut-être pas le déficit en pyruvate kinase (PK). C'est une maladie enzymatique héréditaire rare qui affecte la glycolyse utilisée par les globules rouges pour fabriquer de l'énergie. Elle se manifeste par une anémie hémolytique. Les symptômes varient énormément d'un individu à l'autre, ce qui rend le diagnostic difficile. Et la gestion de cette maladie consiste essentiellement en des traitements de soutien. Rédigé par des experts dans le domaine, 'Fast Facts : Déficit e...

You may be unfamiliar with pyruvate kinase (PK) deficiency. It is a rare inherited enzyme disorder that affects the glycolytic pathway used by red blood cells to generate energy, manifesting as hemolytic anemia. The symptoms vary greatly between individuals, making diagnosis difficult, and management primarily comprises supportive treatments. Written by experts in the field, 'Fast Facts: Pyruvate Kinase Deficiency' provides a comprehensive introduction to the condition, including details o...

Comprehensive in scope and thoroughly up to date, Wintrobe’s Clinical Hematology, 15th Edition, combines the biology and pathophysiology of hematology as well as the diagnosis and treatment of commonly encountered hematological disorders. Editor-in-chief Dr. Robert T. Means, Jr., along with a team of expert section editors and contributing authors, provide authoritative, in-depth information on the biology and pathophysiology of lymphomas, leukemias, platelet destruction, and other hematol...

Pyruvate kinase (PK) deficiency is an inherited disease that affects red blood cells and manifests as hemolytic anemia. It is a lifelong condition, with symptoms that range from mild to severe. Despite an ever-growing understanding of its pathophysiology, etiology, and epidemiology, and an active research program, PK deficiency remains unfamiliar to many medical practitioners. PK deficiency is clinically heterogeneous, so healthcare professionals need to consider the possibility of this di...

You may be unfamiliar with pyruvate kinase (PK) deficiency. It is a rare inherited enzyme disorder that affects the glycolytic pathway used by red blood cells to generate energy, manifesting as hemolytic anemia. The symptoms vary greatly between individuals, making diagnosis difficult, and management primarily comprises supportive treatments. Written by experts in the field, 'Fast Facts: Pyruvate Kinase Deficiency' provides a comprehensive introduction to the condition, including details o...

The landmark text that has guided generations of hematologists and related practitioners―updated with the latest research findings and improved format and presentationLong revered for its comprehensiveness and extraordinary depth of detail, Williams Hematology provides essential coverage of the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood and marrow cells and coagulation proteins. The text contains a wealth of ba...

The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism. - Inve...

This comprehensive, full color hematopathology reference book emphasizes immunophenotpic features, cytogenetic studies, and diagnostic molecular aspects. Hematopathology begins with introductions to morphologic evaluation of the hematopoietic tissues and principles of immunophenotyping, cytogenetics and molecular studies followed by chapters dedicated to different types of hematologic disorders. Each chapter starts with a basic overview of hematopathlogy followed by a comprehensive review ...

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.The world's most highly regarded reference text on the mechanisms and clinical management of blood diseasesA Doody's Core Title for 2020!Edition after edition, Williams Hematology has guided generations o...

The epidemiological and clinical importance of bone metastasis has long been recognized, but the past decade has seen an explosion in the fields of bone biology and bone cancer research. This period of time has been marked by a number of key discoveries that have led to the opening up of entirely new areas for investigation as well as new therapies which combine surgery and biological therapeutic approaches.Bone is a common site of cancer metastases - cancer cells commonly develop in bone ...

Emerging Cancer Therapeutics is a trinary hard cover periodical that is designed to provide an up-to-date evidence-based review of a dedicated emerging cancer therapy topic of interest to clinicians and scientists involved in the care of patients receiving cancer treatment. It will serve as both a reference and instructional tool for students, housestaff, fellows, practicing clinical oncologists, radiation oncologists, surgical oncologists, cancer biologists, and interdisciplinary...