In recent years, the use of bioconjugation as strategy for development of more specific and directed drugs has been widely researched. Tetrapyrrolic macrocycles are one of the most common families of organic compounds applied in medicinal chemistry, specifically for diagnosis and therapy. For optimization of their efficiency as therapeutic molecules, it is relevant to promote their linking to biomolecules capable of targeting altered cells. This work brings a new dimension to the literatur...

The incidence of multiple pregnancies has increased with the increasing use of assisted reproductive techniques. This super-specialty title intends to cover basic epidemiology, associated complications and management of multiple pregnancy. The aim of this book is to provide a comprehensive, up to date and an evidenced-based discussion of multiple pregnancy and recent advances in its management. The chapters are divided in such a way that all three trimesters are discussed separately with a...