Human Ageing: A Unique Experience explores the biology of human ageing focusing on the individual. The book begins with the premature ageing disorder Hutchinson-Gilford Progeria syndrome and spins a web of interconnected biological domains involving lamins, telomeres, alternative splicing, genetics, epigenetics, and molecular clocks. The profound influence of culture is explored since cultural inheritance and genetic inheritance are the two intertwined processes driving human evolution. An...

NEW YORK TIMES BESTSELLER • From the author of The Untethered Soul and Living Untethered comes the astonishing true-life story about the spiritual harmony and personal happiness he found when he just let go.“With his hallmark precision and clarity Michael Singer reveals how everyday life, doing business in the world, and spiritual practice can be synchronized to carry us into the heart of life’s unimaginable perfection.”—Jack Canf...

NEW YORK TIMES BESTSELLER • 20th Anniversary Edition, with a new foreword by the author • “[A] masterpiece . . . an astonishing book that will leave you questioning your own life and political views.”—USA Today“If any one person can be given credit for transforming the medical establishment’s thinking about health care for the destitute, it is Paul Farmer. . . . [Mountains Beyond Mountains] inspires, discomforts, ...

Thorough and compassionate information about dementia and Alzheimers for caregivers and people with early dementia.As the population continues to age, so too the numbers of people with dementia and Alzheimers grow. Inevitably, it will affect everyone in some way . . . as sufferers, or as carers, or as part of the wide circle of family, friends, professional and voluntary workers needed to support the main caregiver. The effects of dementia spread far into the community.Based on Dr Chris Pe...

This book, featuring content from the Aug 11, 2012, issue of The Lancet, has been released to coincide with the European Society of Cardiology (ESC) meeting in Munich, Germany, which is to be held on Aug 25–29, 2012. The Lancet is strongly supportive of cardiology as can be seen from the substantial relevant content in this compilation. In 2011, The Lancet published more papers in this specialty than any other: cardiovascular research contributed about one in four of all published research...

Down syndrome is a genetic condition which causes varying degrees of learning disability as well as other health problems. Nearly one baby in every 1000 born in the UK has the condition. Parents are often frightened and confused by the birth of a baby with Down syndrome, and they need reassurance as well as up-to-date information regarding the condition. The new edition of this highly regarded book for parents of children with Down syndrome covers a number of important new developments in ...

The American Diabetes Association/JDRF Type 1 Diabetes Sourcebook serves as both an evidence-based reference work and consensus report outlining the most critical components of care for individuals with type 1 diabetes throughout their lifespan. The volume serves not only as a comprehensive guide for clinicians, but also reviews the evidence supporting these components of care and provides a perspective on the critical areas of research that are needed to improve our understanding...

This authored text-reference will be the first comprehensive text in the rapidly growing field of psychological trauma and posttraumatic stress disorder.According to the NIMH, approximately 5.2 million American adults already suffer from post traumatic stress disorder. Caused by everything from combat experience to violent personal assaults to natural disasters and accidents, the incidence of PTSD has already reached epidemic proportions. The profound impact of psychological trauma and the...

This issue of Clinics in Geriatric Medicine, guest edited by Dr. Elsa S. Strotmeyer, is devoted to Medical Complications of Diabetes in Older Adults. Articles in this issue include: Glucose Dysregulation: Pathophysiology and Prevention; Diabetic Medications and Polypharmacy; Physical Function and Disability; Diabetes and Osteoarthritis; Adiposity, Muscle Mass, and Diabetes; Exercise and Weight Loss in Diabetes Management; Diabetes and Cognition; Diabetes and Depression; Sleep Apnea and Dia...

Metabolic bone degeneration (osteoporosis) affects millions of people--primarily postmenopausal women--and is directly responsible for debilitating hip, vertebral, and limb fractures in the elderly. Incorporating advances made within just the past five years, The Osteoporotic Syndrome: Detection, Prevention, and Treatment serves as an up-to-date, practical guide to the major clinical aspects of osteoporosis. The text is liberally illustrated with detailed figures. As a resource for the cli...

Agrammatism provides an overview of the state of knowledge on agrammatism, typically defined as a disorder of sentence production involving the selective omission of function words and some grammatical endings on words. The book opens with discussions of the diversity of the disorder. This is followed by separate chapters that address primarily questions of syntactic structure in agrammatism, from both linguistic and psycholinguistic perspectives. Within these two gross sections there is n...