The Guest Editors have assembled top international experts to present clinical reviews on the most current data being utilized in the diagnosis, treatment, and management of HBV. In fact, the most recent EASL meeting fndings are included in many of the articles. Special focus is given to Results of Treatment of Chronic Hepatitis B with Pegylated Interferon; Impact of Therapy on the Long Term Outcome of Chronic Hepatitis B; HBsAg Quantification: Clinical; HBV Infection and Hepatocellular Ca...

This book, based on the experience of a single large referral center, presents the characteristic findings obtained when using MR imaging and MR cholangiopancreatography (MRCP) to image the biliary tree and pancreatic ducts in a variety of disease settings. An introductory chapter is devoted to technical considerations, anatomy, and developmental anomalies. Subsequent chapters then present in detail the MR imaging and MRCP findings observed in choledocholithiasis, inflammatory and neoplast...

The fourth edition of this authoritative text covers every aspect of liver disease affecting infants, children and adolescents. As in the previous editions, it offers an integrative approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. All of the chapters are written by international experts and address the unique pathophysiology, manifestations and management of these disorders. This edition ...

The liver blood flow disorders are usually described under the term 'portal hypertension', which is a well known syndrome since it has been widely studied for years from a clinical, radiological and therapeutic point of view. In fact, portal hypertension is only the result of an obstacle to the portal flow, the clinical manifestations of which often occur at a late stage of the disease: bleeding esophageal varices, splenomegaly, ascites. In addition, it is well known that there is not alwa...

Basic research discusses the implication of pancreatic stress protein in acute pancreatitis and pancreatic cancer and their possible role as therapeutic targets. Also, very original results show the unexpected role of lipids as mediators during acute pancreatitis. Gene screening strategies allow the detection of the genes responsbile for gemcitabine resistance of pancreatic cancer cells. They lead to the selection of several target genes, in order to suppress the resistance of cells to gem...

The Manual of Upper Gastrointestinal Surgery was compiled as an aid to surgeons, residents, and students who want to acquire a broader knowl edge of the surgical techniques used in the upper gastrointestinal area. Of necessity, a considerable amount of the work of a general surgeon will be confined to this region. The techniques described herein are those preferred by the authors and most, but not all, of their colleagues at the Mayo Clinic. No attempt has been made to include all of the a...

The inadequate supply of organs in the United States and other countries continues to drive the reliance on living donor transplantation. In 2000, representatives of the transplant community convened for a meeting on living donation in an effort to provide guidelines to promote the welfare of living donors. The consensus statement that resulted from this meeting recommended that transplant centers retain an Independent Living Donor Advocate (ILDA) to focus on the best interest of the donor...

This book describes the techniques of percutuneous access to the gallbladder for the treatment of gallstones. It considers the indications, contraindications and complications of the various routes to the gallbladder for the treatment of gallstones.

This is the first volume in a new Springer series, Pathology for Clinicians, which aims to assist clinicians in their daily decision making by providing reliable, clearly presented information on current techniques in pathology, their uses and indications, clinical–pathologic correlations, and the significance of pathologic diagnoses*. Liver Pathology for Clinicians* first discusses key technical aspects of liver biopsy, including the use of special stains and immunohistochemistry. Detaile...

The LEC strain of rats, which spontaneously develop acute hepatitis as sociated with jaundice, chronic hepatitis, and ultimately hepatocellular carcinomas, was established by scientists in Sapporo, Japan. Careful ob servation and breeding led to the initial discovery of this characteristic, inherited liver disease in rats. Subsequent collaboration between scientists in Sapporo and other centers has revealed an autosomal recessive nature of inheritance, along with a variety of histopatholog...

Diseases of the Liver in Children: Evaluation and Management provides a comprehensive, state-of-the art review of pediatric liver disease, with a practical approach useful for the primary care provider or general gastroenterologist. With an emphasis on tables and images, this book serves as a reference for understanding basic hepatic processes and the significance of laboratory findings. It also discusses the state of the art of diagnosis and treatment of diseases that affect the ...

Since the beginnings of diagnostic ultrasound in the 1950s, each decade has seen significant advances in this technology. Commer cialization of ultrasound occurred during the 1960s with the introduction of many of the clinical uses that are in existence today. The 1970s showed the most dramatic changes with the commercial introduction of gray-scale and real-time ultrasound. In the 1980s many new advances were introduced, including color Doppler, as well as a wide variety of endoluminal app...