Chronic deep brain stimulation (DBS) has been a rapidly evolving area of neurotherapeutics since its initial introduction for the treatment of Parkinson’s disease and essential tremor in the 1990s. For these conditions, DBS is now considered accepted therapy for patients failing to adequately respond to m- ical treatment. Since the 1990s, new clinical indications, anatomic targets, and technologies have contributed to an expanding role for DBS in the treatment of other movement disorders s...

Originally published in 1985. This book examines the scope of the industry and also focuses on issues relevant to it, divided into three sections: an overview of the American nuclear power industry, an examination of the nuclear power plant licensing process and issues that face the nuclear industry, and selected case studies that illustrate issues discussed in the previous section.The growth and future of the nuclear power plant industry is discussed and industry-wide trends and r...

Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters...

The fourth edition of Fundamental Neuroscience reinvents itself as an engrossing and comprehensive presentation of the discipline of neuroscience, from molecules to cognition. Thorough but succinct, and lavishly illustrated, the book builds from an introductory section that includes fundamental neuroanatomy and goes on to cover cellular and molecular neuroscience, development, sensory systems, motor systems, regulatory systems, and behavioral and cognitive neuroscience. The book h...

Epilepsy is the most common serious neurological condition, affecting children and adults, and can occur in a variety of medical settings. It has many causes and many forms, and a variable prognosis. Mortality and morbidity are high, social and legal consequences can stretch well beyond the purely medical, and its management is often poor. Part of the Oxford Textbooks in Clinical Neurology (OTCN) series, this volume covers the scientific basis, clinical diagnosis, and treatment of epilepsy...

Epilepsy, Part I, Basic Principles and Diagnosis, Volume 107, in the Handbook of Clinical Neurology series offers a comprehensive review of our knowledge of the field today, including epidemiology, basic mechanisms, animal models, and topics of increasing interest such as the role of inflammation in epilepsy. It provides a comprehensive approach to description of the clinical, electrographic and imaging aspects of the epilepsies, with a clear outline of contemporary classification and the ...

Epilepsy, Part II, Treatment, Volume 108, provides a full description of epilepsy pathology and etiology, antiepileptic drug treatment, the approach to surgical evaluation and alternative procedures to be considered, in both children and adults, as well as brain stimulation and diet treatment. Economic and psychosocial issues such as stigma are fully covered. The special problems of epilepsy treatment in the developing world are described. Chapters are authored by internationally respected...

Recent developments in basic and applied science have led to better understanding of disease mechanisms and more efficient therapies for multiple sclerosis. The most effective way of managing these patients is through a carefully planned neurorehabilitation programme. The main aims are to reduce disability and handicap and improve functions through effective training, stimulating activity and social participation. As the first text on recovery of function and neurorehabilitation in MS, thi...

In his trademark, revolutionary style, Dr. Goldstein uses his model of neural dysregulation to incorporate basic neuroscience research into pathophysiology and treatment. Betrayal by the Brain presents a comprehensive thesis that clearly defines the biological basis for many of the varied symptoms experienced by chronic fatigue syndrome patients. Dr. Goldstein provides a rationale for the use of symptomatic therapies that have worked in many CFS patients. Betrayal by the Brain is a valuabl...

Development of the brain and the emergence of the mind constitute some of the most important concerns of contemporary biology. Disturbances during fetal life may have profound implications for a child's future neurological and psychological development, which can in turn impact society. The new edition of this highly respected work presents a comprehensive review of the basic mechanisms of brain development and the pathophysiology of disorders of the infant brain, written by a team of dist...

"This book, in both its direct and indirect inferences, points to the need for disease-specific neurocognitive methods in broadly occurring CNS and non-CNS cancers... All in all, this is a beautifully conceptualized book that should be on the bookshelves of many specialists who work in the very challenging field of Oncology."--Carol L. Armstrong, PhD, Children's Hospital of Pennsylvania, Archives of Clinical NeuropsychologyInterest in the neurocognitive and sensory...

Increasingly, electroconvulsive therapy (ECT) is recognized as a proven, effective, and even life-saving intervention in certain mood and thought disorders when other treatments have had little or no effect. Despite the proven efficacy and safety of this standard treatment in psychiatry, its availability is variable. Part of this disparity in access is related to misunderstanding by laypersons regarding the treatment and its potential adverse effects. Adequate education and training of psy...