In recent years there has been steadily increasing interest in motor behavior and a growing awareness that a person not only has to know what to do in a particular situation, but also how to do it. The question of how actions are performed is of central concern in the area of motor control. This volume provides an advanced-level treatment of some of the main issues. Experiments concerned with basic processes of motor control typ ically examine very simple movements. At first glance these t...

This book is the fruit of a study group on perception and action that worked at the Center for Interdisciplinary Research (ZiP) of the University of Bielefeld, FRG in the academic year 1984-1985. We express our gratitude to the ZiF for hosting the group and for providing fmancial and organizational support for its scientific activities, including a meeting of the authors of the present volume that took place at the ZiF in July 1986. This is/ the study group's last common product, and it to...

An original interdisciplinary study positioned at the intersection of literary theory and neuroscience."Literature matters," says Paul B. Armstrong, "for what it reveals about human experience, and the very different perspective of neuroscience on how the brain works is part of that story." In How Literature Plays with the Brain, Armstrong examines the parallels between certain features of literary experience and functions of the brain. His central argumen...

This book provides comprehensive and up-to-date information on the neuropsychiatric disturbances that may be experienced by patients with multiple sclerosis. The first section is designed primarily to describe the general clinical aspects of multiple sclerosis, from epidemiology to assessment tools. The role of neuroimaging and especially MRI is then explained, and treatment approaches and rehabilitation strategies are described. The core section of the volume is the second, in which the v...

This book combines classic MR anatomy with current understanding of human brain function. Recent advances in neuroscience have highlighted the importance of correlating brain anatomy with underlying brain function, since the brain contains a highly sophisticated organization of anatomical and functional relationships that are not readily “visible” with standard imaging. The use of magnetic resonance imaging is rapidly increasing in the field of neuroscience, and remains at the forefront fo...

Encephalopathy and Nitrogen Metabolism in Liver Failure contains research reports and state-of-the-art reviews that were presented at the 11th International Symposium on Hepatic Encephalopathy and Nitrogen Metabolism in relation to liver disease, that was held in Amsterdam, The Netherlands from 30 May to 1 June, 2002. Themes covered include the metabolism of ammonia and amino acids in relation to liver disease, the assessment of hepatic encephalopathy (HE), minimal HE, ani...

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biolog...

The Springer Handbook of Bio-/Neuro-Informatics is the first published book in one volume that explains together the basics and the state-of-the-art of two major science disciplines in their interaction and mutual relationship, namely: information sciences, bioinformatics and neuroinformatics. Bioinformatics is the area of science which is concerned with the information processes in biology and the development and applications of methods, tools and systems for storing and processi...

This volume will provide an important contemporary reference on hearing development and will lead to new ways of thinking about hearing in children and about remediation for children with hearing loss. Much of the material in this volume will document that a different model of hearing is needed to understand hearing during development. The book is expected to spur research in auditory development and in its application to pediatric audiology.

The evolution of vertebrate hearing is of considerable interest in the hearing community. However, there has never been a volume that has focused on the paleontological evidence for the evolution of hearing and the ear, especially from the perspective of some of the leading paleontologists and evolutionary biologists in the world. Thus, this volume is totally unique, and takes a perspective that has never been taken before. It brings to the fore some of the most recent discoveries among fo...

As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from th...