Mathematical modelling and computer simulations are playing a crucial role in the solution of the complex problems arising in the field of biomedical sciences and provide a support to clinical and experimental practices in an interdisciplinary framework.Indeed, the development of mathematical models and efficient numerical simulation tools is of key importance when dealing with such applications.Moreover, since the parameters in biomedical models have peculiar scientific in...

This work collects the contributions presented at the INdAM Workshop “Mathematical modeling and Analysis of degradation and restoration in Cultural Heritage – MACH2019” held in Rome in March 2019. The book is focused on mathematical modeling and simulation techniques with the aim of improving the current strategies of conservation and restoration in cultural heritage, sharing different experiences and approaches. The main topics are: corrosion and sulphation of materials, damage and fractu...

This volume gathers contributions reflecting topics presented during an INDAM workshop held in Rome in May 2016. The event brought together many prominent researchers in both Mathematical Analysis and Numerical Computing, the goal being to promote interdisciplinary collaborations. Accordingly, the following thematic areas were developed:Lagrangian discretizations and wavefront tracking for synchronization models;Astrophysics computations and post-Newton...

Light and Skin Interactions immerses you in one of the most fascinating application areas of computer graphics: appearance simulation. The book first illuminates the fundamental biophysical processes that affect skin appearance, and reviews seminal related works aimed at applications in life and health sciences. It then examines four exemplary modeling approaches as well as definitive algorithms that can be used to generate realistic images depicting skin appearance. Despite its wide scope...

Modelling Methodology for Physiology and Medicine, Second Edition, offers a unique approach and an unprecedented range of coverage of the state-of-the-art, advanced modeling methodology that is widely applicable to physiology and medicine. The second edition, which is completely updated and expanded, opens with a clear and integrated treatment of advanced methodology for developing mathematical models of physiology and medical systems. Readers are then shown how to apply this methodology b...

Radiation therapy has developed and advanced dramatically in the last few decades. However, very little has been published or done in the area of biologically optimized treatment planning. Development of Biologically Optimized Radiation Therapy aims to fill and close an important gap in the literature with a well-focused and in-depth content.The book covers the biological, physical and clinical background of advanced biologically based radiation therapy optimization with focus on modern ra...

This book is based on the papers presented at the 6th International Conference on Numerical Methods in Geomechanics in Innsbruck from 11–15 April 1988. It presents a derivation of an analytical method in due consideration of mechanical interaction between groundwater and surrounding ground.

PET and SPECT are two of today's most important medical-imaging methods, providing images that reveal subtle information about physiological processes in humans and animals. Emission Tomography: The Fundamentals of PET and SPECT explains the physics and engineering principles of these important functional-imaging methods. The technology of emission tomography is covered in detail, including historical origins, scientific and mathematical foundations, imaging systems and their components, i...

The book gathers articles that were exposed during the seventh edition of the Workshop “Data Analysis in Astronomy”. It illustrates a current trend to search for common expressions or models transcending usual disciplines, possibly associated with some lack in the Mathematics required to model complex systems. In that, data analysis would be at the epicentre and a key facilitator of some current integrative phase of Science.It is all devoted to the question of “representation in Science”, ...

The development of innovative drugs is becoming more difficult while relying on empirical approaches. This inspired all major pharmaceutical companies to pursue alternative model-based paradigms. The key question is: How to find innovative compounds and, subsequently, appropriate dosage regimens?Written from the industry perspective and based on many years of experience, this book offers:- Concepts for creation of drug-disease models, introduced and supplemented with extens...

Read an exclusive interview with Dr. Jerry Battista here.A critical element of radiation treatment planning for cancer is the accurate prediction and delivery of a tailored radiation dose distribution inside the patient. Megavoltage x-ray beams are aimed at the tumour, while collateral damage to nearby healthy tissue and organs is minimized. The key to optimal treatment therefore lies in adopting a trustwort...

The book provides an insight into the advantages and limitations of the use of fractals in biomedical data. It begins with a brief introduction to the concept of fractals and other associated measures and describes applications for biomedical signals and images. Properties of biological data in relations to fractals and entropy, and the association with health and ageing are also covered. The book provides a detailed description of new techniques on physiological signals and images based o...