The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, the...

Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin ...

If you've ever felt a crumpling in your chest when another friend tells you that they're pregnant… If you've ever wondered why everyone else seems to find it so easy… If you've ever experienced the pursuit of motherhood… This book is for you.It is currently estimated that one in five couples have difficulty conceiving. Hepburn’s book which describes her long and, at times, heartbreaking journey to have a child has been called a cross between Bridget Jones' Diary and Ea...

How pathbreaking research into the brain's connections to the immune system offers new hope for treating diseases, injuries, and the effects of aging.PROSE Awards Honorable Mention, Biomedicine & Neuroscience categoryIn the past, the brain was considered an autonomous organ, self-contained and completely separate from the body's immune system. But over the past twenty years, neuroimmunologist Michal Schwartz, together with her research team, not only...

Immunosenescence is a unique, multi-disciplinary approach to the understanding of immune aging. It addresses the topic from the biological, as well as the psychological, social and behavioral perspectives. It is, thus, a valuable and timely addition to the literature in this area. Contributors include experts in the field, reviewing the state of the art in research.

With an ageing population, there is little doubt that the majority of hospital-based consultants and their teams will care for older patients and the many complications this presents. This book provides an evidence-based guide for both trainees and consultants in geriatric medicine and those interested in geriatric medicine. Designed in line with the core Royal College curriculum, it provides a comprehensive and relevant guide to the issues seen in everyday geriatric medicine practice acro...

This book reports the text of the lectures of the 6th International Conference on Sodium Calcium Exchange held in Lacco Ameno in the Island of Ischia in the Gulf of Naples, Italy, from October 1 to October 5, 2011.The present book uncovers the most striking new findings on NCX that emerged since the previous Conference on Sodium Calcium Exchange, such as the structural dissection of the molecular determinants of Ca2+ sensitivity of the exchanger, the epigenetic regulation of nc...

This book provides a comprehensive overview on current histamine and histamine receptor research in context of human health and disease and reflect the multidisciplinary nature of the field. While the editors realize that it is almost impossible to cover the field completely within the constraints of a single HEP volume, nonetheless, all important aspects will be covered in one way or the other. An overarching introductory chapter will link the individual chapters and provide an overview o...

Caring for elders outside of institutions is the fastest growing sector of US health care. Building on their research study at the Park Ridge Center, editors Holstein and Mitzen, together with a team of experts, examine the complexities involved in developing an ethics for community-based long-term care. They also challenge policymakers to make home care a more viable option for older people in need. Chapters address many of the ethical and practical problems that arise in the care of olde...