What if the life you built disappeared overnight-and you had to create a new one from the ground up?In 2004, Dr. Simon Kirby was living the life he had worked decades to achieve. A successful facial plastic surgeon, husband, father, and lifelong high achiever, he appeared to be at the peak of his profession. Then a catastrophic vertebral artery dissection triggered a brainstem stroke that stopped his heart, left him in a coma, and stripped away nearly everything he...

This audio edition features original music composed and recorded for the audiobook.How does a family pick up the pieces, when the one person who held them all together has gone?When forty-year-old Rabbit Hayes dies, she leaves behind a family broken by grief. Her mother Molly is distraught and in danger of losing her faith. Her father Jack spends hour upon hour in the family attic, poring over his old diaries, losing himself in the past.

This book is about the most important lessons I have learned in my life . . .Dr Maureen Gaffney has long been admired for her ability to combine rigorous psychological insight with clarity and real-world understanding. Now, in About Life, she has distilled the key insights of her career into an urgent book for the times we are living through.In About Life, Dr Gaffney brings together research, a lifetime of observation and her own personal experience to expl...

This book offers a high-level treatise of evidence-based decisions in drug development. Because of the inseparable relationship between designs and decisions, a good portion of this book is devoted to the design of clinical trials. The book begins with an overview of product development and regulatory approval pathways. It then discusses how to incorporate prior knowledge into study design and decision making at different stages of drug development. The latter include selecting appropriate...

When Keelin Shanley passed away aged 51, it was hard to grasp that someone so filled with life was gone. But a light so bright never really goes out, especially since in her last few months Keelin left behind this remarkable record of her life – a life cut short, but lived to the fullest. Charting the twists and turns of both a career as an investigative journalist and a lengthy battle with cancer, A Light That Never Goes Out reveals with real honesty what it’s like to keep living your lif...

This book focuses on important decision points and evidence needed for making decisions at these points during the development of a new drug. It takes a holistic approach towards drug development by incorporating explicitly knowledge learned from the earlier part of the development and available historical information into decisions at later stages. In addition, the book shares lessons learned from several select examples published in the literature since the publication of the first editi...

It was a celebration to die for . . .What happened on holiday was supposed to stay on holiday - but that was before a body was found . . .Socialite Lucinda Oliver planned a lavish celebration for her fortieth birthday - a weekend escape at an Irish coastal town with her sister Stella and her closest friends. The weekend was to end with a blow-out party and a special announcement, one Lucinda had been dropping hints about for weeks.But before Lucinda could reveal her...

Collects Amazing Spider-Man (1963) #97, Howard the Duck (1976) #8, Iron Man (1968) #128, New Mutants (1983) #45, Alpha Flight (1983) #106, Uncanny X-Men (1981) #303, Incredible Hulk (1968) #420, Amazing Spider-Man (1999) #36, Captain America (2002) #1, Astonishing X-Men (2004) #51, Ms. Marvel (2015) #13, Champions (2016) #24; material from Captain America Comics #2, Amazing Spider-Man (1999) #583. The Marvel Universe has always reflected the world outside your window — from the moment Capt...

Collects Captain America Comics (1939) #1-4. Relive the earliest adventures of Captain America, Sentinel of Liberty! Return to the Golden Age of comics as Cap and Bucky come face to face with the Red Skull, the Ringmaster of Death, and more!

Asperger Syndrome has become an increasingly common disorder. One in 300 individuals may have AS—exhibiting characteristics such as average to high intelligence, obsessive behavior, intense special interests, and difficulty dealing with everyday social situations—and it is now more prevalent than childhood cancer and Down’s syndrome.As the mother of a boy diagnosed with AS in 1994, Barbara Kirby found scant resources and support. She developed the internationally renowned OASIS (On...

From the winner of the Nobel Prize in Literature and author of the Booker Prize–winning novel The Remains of the Day comes an inspired sequence of stories as affecting as it is beautiful.With the clarity and precision that have become his trademarks, Kazuo Ishiguro interlocks five short pieces of fiction to create a world that resonates with emotion, heartbreak, and humor. Here is a fragile, once famous singer, turning his back on the one thing he loves; a...

The global order, based on international governance and multilateral trade mechanisms in the aftermath of the Second World War, is changing rapidly and creating waves of uncertainty. This is especially true in higher education, a field increasingly built on international cooperation and the free movement of students, academics, knowledge, and ideas. Meanwhile, China has announced its plans for a "New Silk Road" (NSR) and is developing its higher education and research systems at speed. In ...