This book illustrates recent advances in developing sensitive and selective electrochemical biosensors for their whole blood application. Known to be a cutting-edge and fast-growing technology, electrochemical biosensors demonstrate their potential in laboratories, industries, and healthcare to achieve specific and direct target detection in complex media, and have become an emerging technology for guiding personalized medicine. The book first demonstrates methods and models to cover the d...

This book shows the various sandwich assays that are constructed from recognition molecules, such as antibodies, oligonucleotide sequences and aptamers, developed as a result of nano- and biotechnology advances. It consists of ten chapters presenting interesting examples of these assays, organized according to the type of analytic methods (colorimetric, fluorescence, electrochemical, etc.) and detected objects (protein, nucleic acid, small-molecule, ion, etc.). It also includes a chapter d...

The application of nanotechnology in the biomedical field, known as nanomedicine, has gained much interest in the recent past as a versatile strategy for selective drug delivery and diagnostic purposes. The nanotheranostic approach, which aims to combine both therapeutic and imaging/diagnostic functionalities, is characterized by a strong pluridisciplinarity where the chemistry of materials, bioconjugate chemistry, pharmaceutical technology, drug delivery, imaging, and pharmacology, work t...

Handbook of Immunoassay Technologies: Approaches, Performances, and Applications unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays, to the smartphone-based point-of-care formats. The advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, d...

Functionalized Conjugated Polyelectrolytes presents a comprehensive review of these polyelectrolytes and their biomedical applications. Basic aspects like molecular design and optoelectronic properties are covered in the first chapter. Emphasis is placed on the various applications including sensing (chemical and biological), disease diagnosis, cell imaging, drug/gene delivery and disease treatment. This book explores a multi-disciplinary topic of interest to researchers working i...

This book explores the potential of nanosystems as a multidisciplinary science with the aim of the design and development of smart sensing technologies using micro/nano electrodes and novel nanosensing material. It discusses their integration with MEMS, miniaturized transduction systems, novel sensing strategies, and wearable sensors performing at POC for diagnostics and personalized health care monitoring. It presents basic concepts pertaining to nanobiosensor fabrication, developments in...

This book provides a compressive overview of nanotechnology in modern drug discovery for students and researchers. The book starts with the fundamentals of nanotechnology followed by nanomaterials in pharmaceutical drug design, drug delivery applications, regulatory aspects, formulation and nanoparticle biotransformation. It provides a step by step guide through the drug development process while conveying information about the benefits of nanomaterials for therapy. The book concludes with...

This book provides a comprehensive overview of the potential use of graphene-based materials in two important societal areas: medicine and the environment. It discusses how new graphene-based materials can be creatively used for biological purposes, for example as delivery vehicles for diagnostics or therapeutics, ultrasensitive sensors, smart responsive substrates for artificial-tissue design and biomarkers. Moreover, it presents new insights into their use as sorbent or photocatalytic ma...

Nanotechnology and Biosensors shows how nanotechnology is used to create affordable, mass-produced, portable, small sized biosensors to directly monitor environmental pollutants. In addition, it provides information on their integration into components and systems for mass market applications in food analysis, environmental monitoring and health diagnostics. Nanotechnology has led to a dramatic improvement in the performance, sensitivity and selectivity of biosensors. As metal-oxide and ca...

Iron Oxide Nanoparticles for Biomedical Applications: Synthesis, Functionalization and Application begins with several chapters covering the synthesis, stabilization, physico-chemical characterization and functionalization of iron oxide nanoparticles. The second part of the book outlines the various biomedical imaging applications that currently take advantage of the magnetic properties of iron oxide nanoparticles. Brief attention is given to potential iron oxide based therapies, while the...

Metal Oxides for Biomedical and Biosensor Applications gives an in-depth overview of the emerging research in the biomedical and biosensing applications of metal oxides, including optimization of their surface and bulk properties. Sections cover biomedical applications of metal oxides for use in cell cultures, antibacterial and antimicrobial treatments, dental applications, drug delivery, cancer therapy, immunotherapy, photothermal therapy, tissue engineering, and metal oxide-based biosens...

This two-part multivolume set provides a comprehensive overview of current achievements in biomedical applications of nanotechnology, including stem cell based regenerative medicine, medical imaging, cell targeting, drug delivery, and photothermal/photodynamic cancer therapy. New approaches in early cancer diagnosis and treatment are introduced with extensive experimental results. In particular, some novel materials have been synthesized with new properties that are most effective in cance...