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Springer Protocols eBook Series

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  • Chemogenomics

    Methods and Protocols

    Edited by Daniel Merk, Apirat Chaikuad ...
    Series series Springer Protocols
    This volume presents both theoretical guidance and protocols on chemogenomics including chemogenomics library assembly, compound profiling, and phenotypic assays. The chapters in this book cover topics such as the assembly and use of Kinase Chemogenomics; data mining for chemogenomic compound candidates; protocols for protein family-focused assay systems to profile chemogenomic compounds; ... Read more

    PHP9,041.89

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  • Chemical Genomics

    Edited by Haian Fu, PhD ...
    Advances in chemistry, biology and genomics coupled with laboratory automation and computational technologies have led to the rapid emergence of the multidisciplinary field of chemical genomics. This edited text, with contributions from experts in the field, discusses the new techniques and applications that help further the study of chemical genomics. The beginning chapters provide an overview of ... Read more

    PHP7,020.99

  • Peptide Therapeutics

    Strategy and Tactics for Chemistry, Manufacturing, and Controls

    Edited by Ved Srivastava ...
    Series Book 72 - Drug Discovery Series
    Peptide therapy has become a key strategy in innovative drug development, however, one of the potential barriers for the development of novel peptide drugs in the clinic is their deficiencies in clearly defined chemistry, manufacturing and controls (CMC) strategy from clinical development to commercialization. CMC can often become a rate-limiting step due to lack of knowledge and lack of a formal ... Read more

    PHP13,859.69

  • Fragment-Based Drug Discovery

    Edited by Steven Howard, Chris Abell ...
    Series Book 47 - Drug Discovery Series
    Fragment-based drug discovery is a rapidly evolving area of research, which has recently seen new applications in areas such as epigenetics, GPCRs and the identification of novel allosteric binding pockets. The first fragment-derived drug was recently approved for the treatment of melanoma. It is hoped that this approval is just the beginning of the many drugs yet to be discovered using this ... Read more

    PHP13,138.99

  • Fundamentals of Advanced Omics Technologies: From Genes to Metabolites

    by Carolina Simó, Alejandro Cifuentes, Virginia García-Cañas ...
    Series Book 63 - Comprehensive Analytical Chemistry
    Fundamentals of Advanced Omics Technologies: From Genes to Metabolites covers the fundamental aspects of the new instrumental and methodological developments in omics technologies, including those related to genomics, transcriptomics, epigenetics, proteomics and metabolomics, as well as other omics approaches such as glycomics, peptidomics and foodomics. The principal applications are presented in ... Read more

    PHP13,675.49

  • A Practical Guide to Protein Engineering

    by Tuck Seng Wong, Kang Lan Tee ...
    Series series Biomedical and Life Sciences (R0)
    This textbook introduces readers in an accessible and engaging way to the nuts and bolts of protein expression and engineering. Various case studies illustrate each step from the early sequence searches in online databases over plasmid design and molecular cloning techniques to protein purification and characterization. Furthermore, readers are provided with practical tips to successfully pursue a ... Read more

    PHP5,166.59

  • Drosophila

    Methods and Protocols

    Edited by Christian Dahmann ...
    Series series Springer Protocols
    This third edition expands on the previous editions by providing updated protocols and current methods that cover recent breakthroughs in Drosophila research. Chapters guide readers through FlyBase, versatile gene expression systems, analysis of microRNA function, single-cell transcriptome data and metabolism, recent applications of CRISPR for precise genome editing, transcriptional activation and ... Read more

    PHP7,846.99

  • Single Cell ‘Omics of Neuronal Cells

    Edited by Jonathan V. Sweedler, James Eberwine, Scott E. Fraser ...
    Series series Springer Protocols
    This volume discusses the latest techniques used in the diverse fields of single cell ‘omics and covers topics such as quantifying the single cell transcriptome; isolation of cells in nanoliter volumes for single cell proteomics measurements by nano-LC-MS/MS; and single cell protein characterization by immunoblotting. A wide range of methodologies are highlighted, ranging from high-yield chemical ... Read more

    PHP9,687.79

  • Modern Proteomics – Sample Preparation, Analysis and Practical Applications

    Edited by Hamid Mirzaei, Martin Carrasco ...
    Series series Biomedical and Life Sciences (R0)
    This volume serves as a proteomics reference manual, describing experimental design and execution. The book also shows a large number of examples as to what can be achieved using proteomics techniques. As a relatively young area of scientific research, the breadth and depth of the current state of the art in proteomics might not be obvious to all potential users. There are various books and review ... Read more

    PHP9,687.79

  • The Proteomics Protocols Handbook

    Edited by John M. Walker ...
    Series series Springer Protocols
    Hands-on researchers describe in step-by-step detail 73 proven laboratory methods and bioinformatics tools essential for analysis of the proteome. These cutting-edge techniques address such important tasks as sample preparation, 2D-PAGE, gel staining, mass spectrometry, and post-translational modification. There are also readily reproducible methods for protein expression profiling, identifying ... Read more

    PHP18,666.39

  • Structural Genomics and Drug Discovery

    Methods and Protocols

    Edited by Wayne F. Anderson ...
    Series series Springer Protocols
    Structural Genomics and Drug Discovery: Methods and Protocols focuses on high throughput structure determination methods and how they can be applied to lay the groundwork for structure aided drug discovery. The methods and protocols that are described can be applied in any laboratory interested in using detailed structural information to advance the initial stages of drug discovery. Written in the ... Read more

    PHP6,458.39

  • Cell-Wide Identification of Metabolite-Protein Interactions

    Edited by Aleksandra Skirycz, Marcin Luzarowski, Jennifer C. Ewald ...
    Series series Springer Protocols
    This thorough volume explores protocols of proteome- and metabolome-wide strategies for the identification of protein-small molecule complexes in different organisms, in order to shed light on these important regulatory interactions. Experimental and computational strategies to characterize protein-metabolite interactions are discussed, and recent advances in enabling technologies are featured as ... Read more

    PHP6,458.39