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  • Target Identification and Validation in Drug Discovery

    Methods and Protocols

    Diziler series Springer Protocols
    This third edition book explores breakthrough techniques in the field of drug target identification and validation. With technologies and methodologies ranging from target identification to the analysis of clinical samples, as well as newer areas like artificial intelligence and machine learning applications, the book will aid decision-makers in drug development by offering a succinct overview of ... Daha fazla okuyun

    TL9.519,83

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  • Mass Spectrometry for the Clinical Laboratory

    Editör: Hari Nair, William Clarke ...
    Mass Spectrometry for the Clinical Laboratory is an accessible guide to mass spectrometry and the development, validation, and implementation of the most common assays seen in clinical labs. It provides readers with practical examples for assay development, and experimental design for validation to meet CLIA requirements, appropriate interference testing, measuring, validation of ion suppression ... Daha fazla okuyun

    TL3.925,79

  • The Design and Development of Novel Drugs and Vaccines

    Principles and Protocols

    The Design and Development of Novel Drugs and Vaccines: Principles and Protocols presents both in silico methods and experimental protocols for vaccine and drug design and development, critically reviewing the most current research and emphasizing approaches and technologies that accelerate and lower the cost of product development. Sections review the technologies and approaches used to identify, ... Daha fazla okuyun

    TL5.891,51

  • IMMUNO-model in Cancer

    Methods and Protocols

    Editör: Sweta Rani, Lukasz Skalniak ...
    Diziler series Springer Protocols
    This open access volume describes the computational and experimental models that help researchers understand the responses of the immune system in cancer and test experimental immune-oncology approaches. The chapters in this book cover methods such as profile polarization in macrophages using ELISA; immune checkpoint inhibitors; interactions of PD-1/PD-L1 and T cells; immunocompetent preclinical ... Daha fazla okuyun

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  • Mass Spectrometry-Based Proteomics

    Editör: Kris Gevaert ...
    Diziler series Springer Protocols
    This detailed volume explores contemporary techniques in mass spectrometry-based proteomics. After covering overall proteome coverage and the cellular surfaceome, the book delves into proximity-induced biotinylation, abduction of protein complexes in viral-like particles, and thermal proteome profiling, as well as protocols for identifying protein N-terminal acetylation, protein processing by ... Daha fazla okuyun

    TL9.420,71

  • Antimicrobial Peptides

    A Roadmap for Accelerating Discovery and Development

    Antimicrobial Peptides: A Roadmap for Accelerating Discovery and Development covers the most important efforts of scientists and engineers worldwide to accelerate the process of discovery, production, and eventual market penetration of more potent antimicrobial peptides. These efforts have been fueled by emerging technologies such as artificial intelligence and data science, molecular and CFD ... Daha fazla okuyun

    TL7.855,43

  • Sterile Product Development

    Formulation, Process, Quality and Regulatory Considerations

    Diziler series Biomedical and Life Sciences (R0)
    This comprehensive book encompasses various facets of sterile product development. Key concepts relevant to the successful development of sterile products are illustrated through case studies and are covered under three sections in this book:• Formulation approaches that discuss a variety of dosage forms including protein therapeutics, lipid-based controlled delivery systems, PEGylated ... Daha fazla okuyun

    TL18.424,67

  • Drosophila

    Methods and Protocols

    Editör: Christian Dahmann ...
    Diziler series Springer Protocols
    This third edition expands on the previous editions by providing updated protocols and current methods that cover recent breakthroughs in Drosophila research. Chapters guide readers through FlyBase, versatile gene expression systems, analysis of microRNA function, single-cell transcriptome data and metabolism, recent applications of CRISPR for precise genome editing, transcriptional activation and ... Daha fazla okuyun

    TL6.803,75

  • Cancer Drug Resistance

    Methods and Protocols

    Editör: Marta Baiocchi ...
    Diziler series Springer Protocols
    This volume discusses the latest techniques used to identify cancer drug resistance determinants at the molecular, cellular, and functional levels. Chapters in this book cover up-to-date topics including tumor-microenvironment cell co-culture methods and microfluidics systems; workflows for functional assessment of drug resistance in vitro and in vivo; quantitative techniques for identifying ... Daha fazla okuyun

    TL6.719,75

  • Golgi

    Methods and Protocols

    Diziler series Springer Protocols
    This volume provides readers with a collection of new and classical methods, techniques, and applications used to address enduring questions about the structure and functions of the Golgi complex. The chapters in this volume cover diverse topics ranging from model systems; live and fixed cell imaging techniques; in vitro biochemical reconstitution systems; and specific methods developed to study ... Daha fazla okuyun

    TL11.704,43

  • Clinical Applications of Nucleic Acid Amplification

    Diziler series Springer Protocols
    This volume details applications, methods, and protocols on nucleic acid amplification. Chapters detail the management of organ and stem cell transplantation, constitutional genetics and genomics, epidemiology, public health, nucleic acid detection, methods for amplification and sequencing, nuclease-assisted mutant allele enrichment, isothermal, and high-throughput sequencing. Written in the ... Daha fazla okuyun

    TL7.839,83

  • Single Cell ‘Omics of Neuronal Cells

    Diziler series Springer Protocols
    This volume discusses the latest techniques used in the diverse fields of single cell ‘omics and covers topics such as quantifying the single cell transcriptome; isolation of cells in nanoliter volumes for single cell proteomics measurements by nano-LC-MS/MS; and single cell protein characterization by immunoblotting. A wide range of methodologies are highlighted, ranging from high-yield chemical ... Daha fazla okuyun

    TL8.399,75