This book is a practical, up-to-date guide to the correct use of lithium for the short- and long-term treatment of mood disorders. Among the subjects addressed are the pharmacology and mechanisms of action of lithium, its use for maintenance treatment, the role of lithium in the treatment of mania and depression and in suicide prevention, further clinical indications, the administration of lithium during pregnancy and the postpartum period, and adverse effects and their management. Relevan...

The past thirty years have witnessed a revolution in the science of addiction, yet we still rely on outdated methods of treatment. Expensive new programs for managing addiction are also flourishing, but since they are not based in science, they offer little benefit to people who cannot afford to lose money or faith in their recovery.Clarifying the cutting-edge science of addiction for both practitioners and general readers, The Thirteenth Step pairs stories of real patient...

"Pharmacology: An Introduction" is a part of the Neuropsychopharmacology course series textbooks. It is a tutorial written in questions and answers format. It is a study guide with in-depth explanations. Each section is a modular unit that is self-contained for easy reading. The principles and concepts are introduced systematically so students can learn and retain the materials intuitively.

The World Health Organization defines depression as a primary contributor to the global burden of disease and predicts it will become the second leading cause of death by 2020. The need to develop effective therapies has never been so pressing. Current antidepressant drugs have several limitations. This 2010 book looks at the future of mood-disorder research, covering the identification of new therapeutic targets, establishing new preclinical models, new medicinal chemistry opportunities, ...

Part of the Drugs in series, the updated second edition of this practical pocketbook summarizes essential information on all the major drugs currently used in clinical psychiatric practice. Beginning with a brief discussion on drugs in psychiatry, the text moves on to consider the principles of psychopharmacology, which form the foundation of the sound, scientifically based use of drugs in psychiatry. Details are then given, in turn, of the main non-depot antipsychotic drugs, antipsychotic...

In this book, the four leading experts on the ACE inhibitors donepezil, galantamine, and rivastigmine and the NMDA receptor antagonist memantine explain the practical pharmacology of these symptomatic drugs with the aim of providing a sound basis for their clinical use in patients with Alzheimer’s disease. In addition, an introductory chapter considers the basic theory of pharmacology for Alzheimer’s disease and the book closes with an overview of the ways in which symptomatic drugs for de...

This issue of Current Topics in Behavioral Neuroscience focuses on the neuropeptide orexin (hypocretin) and brings together scientists from around the world who will provide a timely discussion of how this peptide regulates behavior. This is a fast-moving field, and with the incorporation of novel technologies, new breakthroughs are likely to continue. For example, the use of optogenetic approaches has enabled the identification of the role of orexin-containing neurons in arousal ...

"Dose-Response Curve" is a book chapter of the college-level textbook for the book volume in the Principles of Neuropsychopharmacology course. It is a part of the Science Textbook Series authored by Nicoladie Tam, Ph.D. that also includes the Principles of Biology course.This book is written with specific pedagogical considerations to facilitate students' learning. It applies the proven best practices to motivate students in learning. It uses multiple pedagogical methodologies to e...

During the past two decades, remarkable advances have been made in psychopharmacology, resulting in increased demands for journal space (witness the large number of journals that cater primarily or exclusively to this topic). Concomitantly, a need developed for more integration of the currently available data. To this end, numerous edited volumes in psycho pharmacology have appeared which have been primarily concerned with the role of a particular drug or system in modulating a wide variet...

"Pharmacokinetics" is a part of the Neuropsychopharmacology course series textbooks. It is a tutorial written in questions and answers format. It is a study guide with in-depth explanations. Each section is a modular unit that is self-contained for easy reading. The principles and concepts are introduced systematically so students can learn and retain the materials intuitively.

This book offers a comprehensive but highly readable compilation of papers on the role of dopamine in sleep and sleep disorders. Leading experts in sleep medicine, psychiatry and neuroendocrinology provide a broad perspective on the field, from established theories to the latest research advances. Accordingly, it represents an interdisciplinary, cutting-edge guide for sleep disorder specialists, sleep researchers, psychiatrists, neurologists, pulmonologists, psychologists, and behavioral s...