As a graduate student at MIT, Steve Ramirez successfully created false memories in the lab. Now, as a neuroscientist working at the frontiers of brain science, he foresees a future where we can replace our negative memories with positive ones. In How to Change a Memory, Ramirez draws on his own memories of friendship, family, loss and recovery to reveal how memory can be turned on and off like a switch, edited and even constructed from nothing.A future in which we can chan...

This is the first book to extensively explore the current state-of-the-art and promise of engram cells, the closest physical approximation of the memory trace to date. Converging evidence suggests that memories are stored, at least in part, as specific populations of engram cells. In this book, the leading experts in engram biology share their continuously refined insights on how engram cells contribute to information encoding and storage, across diverse brain regions and behavioral modali...

As a graduate student at MIT, Steve Ramirez successfully created false memories in the lab. Now, as a neuroscientist working at the frontiers of brain science, he foresees a future where we can replace our negative memories with positive ones. In How to Change a Memory, Ramirez draws on his own memories of friendship, family, loss and recovery to reveal how memory can be turned on and off like a switch, edited and even constructed from nothing.A future in which we can chan...

Brought to you by Penguin.How do you rebuild your life when suddenly everything changes?How do you make sense of this new world, this path you didn’t know you had to walk down?When you are sideswiped by a catastrophic sh*t show, the prospect of putting the pieces back together can feel utterly impossible. In these difficult times, we seek comfort and guidance – a way through the pain – and this book will do just tha...

Brought to you by Penguin.Even as the great siege began it was understood by both sides to be an epic – a potentially decisive encounter between an uneasy assortment of soldiers, native Maltese, adventurers and Knights Hospitaller on a strategically crucial but near waterless island and a vast, seemingly all-powerful Ottoman armada. With three quarters of the Mediterranean’s coasts already in the hands of the Sultan and his allies, all eyes were now on Malta.

**Brought to you by Penguin.What does it mean for us all when death is treated as a glitch and Silicon Valley invests in the “science” of eternal life?**From the epic of Gilgamesh to the alchemy of the philosopher’s stone, humanity’s eternal quest for immortality – and its rejuvenation tricks, therapies and tinctures – has always been our most mortal endeavour.But now the giants of invention and investment are building a fountain of youth of their own creation: one ...

**Brought to you by Penguin.Our goal should not be to eliminate vulnerability, but to harness its power. This is a roadmap for figuring out how.**We know the gut-wrenching feeling: that post-conversation replay, cringing at how much we just revealed. We live in fear of saying too much, so we keep quiet, guard our emotions and lock away our most personal thoughts.But what if we’ve been worrying about the wrong thing?A growing body of research shows we vastly ...

'Finding Focus is an essential read for our distracted times' - Dr Mark Hyman'Filled with helpful applications and science-packed insights, this practical guide to improving our mental focus empowers us to create real changes in our daily lives that can improve our mental and physical health' - Dr Daniel J. SiegelOur brains are wired for focus. We are designed for it, we crave it, and yet in our current age of overload we too often...

In this nationally bestselling “delightful compendium of everything you ever wanted to know about” (The Washington Post) Joni Mitchell, the eternal singer-songwriter is seen anew, portrayed through a witty and comprehensive exploration of anecdotes, quotes, lyrics by Henry Alford, “the most graceful of humorists” (Vanity Fair) and a writer for The New Yorker.Joni Mitchell’s life, psyche, and evolving legacy are explored here in “the great...

Brought to you by Penguin.Built by slave labour in the early years of the eighteenth century, Saint Petersburg was Peter the Great’s so-called ‘window on to Europe’, a city that would outdo all of Europe in its splendour. But a window works both ways, and as bestselling historian Sinclair McKay writes, St Petersburg has always been a city that has drawn Westerners who wanted to see into Russia. It is also a city where much has happened. It was St Petersburg until 1...

**Brought to you by Penguin.**THE INSTANT NUMBER 1 SUNDAY TIMES BESTSELLER**What’s stopping you from achieving the success you’ve always wanted?**From growing up in a South London council estate to selling his first business for many millions before he was 30, Timo Armoo didn’t dream of success, he made it happen. Being extraordinary, he proves, really is possible no matter where you start.In What’s Stopping You?, Timo shares the real secrets to overcoming f...

'A hilarious and original voice' Josh Widdicombe'Delightfully smart and impossibly charming' Dolly Alderton'His writing is as unpredictable and brilliant as he is' Sophie Duker'I've got nothing but love for Mr Ivo Graham' Frankie BoyleYardsticks For Failure is the story of the most frantic two years of Ivo Graham's already quite frantic life, 2022-2024, two years of tasks and tears and every...