A number of books and articles have been written ranking the best situation comedies of all time.These have all had something in common--subjective criteria based on the authors' opinions. This book attempts an objective ranking of the best 100 American sitcoms, based on a mathematical formula taking into account four factors: ratings, longevity, peer acceptance and spawning of other programs (spin-offs).The authors considered a field of 377 series which met at least one of...

Recent research suggests that adult growth hormone (GH) deficiency, whether of pathological or physiological origin, is associated with a dis tinct syndrome that includes alterations in body composition, endocrine metabolic function, immune competence, and physical and psychosocial well-being. Not surprisingly, substantial investigative effort is currently focused on validating the above hypothesis and on determining whether restoration of a normal GH-IGF-I axis in various states of adult ...

Today more than ever, series finales have become cultural touchstones that feed watercooler fodder and Twitter storms among a committed community of viewers. While the final episodes of The Fugitive and M*A*S*H continue to rank among the highest rated broadcasts, more recent shows draw legions of binge-watching fans. Given the importance of finales to viewers and critics alike, Howard and Bianculli along with the other contributors explore these endings and what they mean to the audience, ...

Endocrine Emergencies: Recognition and Treatment offers a state-of-the-art update on the management of endocrine, diabetic, and metabolic emergencies. Developed by renowned experts, this comprehensive and easy to read title brings the field fully up to date, setting a high standard for diagnosis and treatment in each category. All chapters begin with a summary that presents, in concentrated form, what the physician needs to know to begin the evaluation and emergency treatment of t...

This book provides a concise yet comprehensive review of the morphological, biochemical, electrical, mechanical, and metabolic properties of vascular smooth muscle, the regulation of vascular activities and the intracellular signaling involved. It particularly focuses on recently identified vasoactive agents, enzymes and transduction mechanisms. It also discusses the latest findings in the regulation of cerebral, coronary and pulmonary circulation as well as vascular activity under hypoxia...

Defining and understanding cellular and molecular mechanisms that are relevant to women’s health has become a critical area of scientific pursuit. Until recently, very little effort has been place on defining or understanding critical differences between women and men that may be critical to the overall health of the woman. In 1990, the National Institutes of Health recognized this gap in knowledge resulting in the creation of the Office of Research on Women’s Health. One of the purposes o...

As the notorious Reva Shayne on the daytime television drama Guiding Light, Kim Zimmer portrayed a vixen, a manic-depressive, an Amish woman, a time traveler, a Civil War belle, a talk show host, a cancer survivor, a loving mother, and a devoted wife. In her more than two decades on the show, she earned eleven Daytime Emmy nominations and four wins, not to mention a legion of loving fans. Now, in this heartfelt memoir, Zimmer delves into her experiences as a daytime diva.P...

Endothelial cell biology has developed into a vibrant discipline and has become a critical instrument to study several disease processes on the cellular and molecular level. It is now widely recognized that dysfunctions of normal endothelial cell homeostasis are involved in some of the most important human diseases, including ischemic heart diseases, hypertension, atherosclerosis, tumors, diabetes, arthritis, and inflammation. Further, the increasing importance and recognition of the field...

Laron syndrome (LS), or primary growth hormone (GH) insensitivity, was first described in 1966. Since then, many patients worldwide have been diagnosed with LS, which involves defects in the GH receptor that cause combined congenital deficiency of GH and IGF-I activities. In this comprehensive book the authors draw upon 50 years of multidisciplinary clinical and investigative follow-up of the large Israeli cohort of LS patients. The genetic basis of the syndrome is fully considered, and al...

The Untold History of Television provides a captivating glimpse behind the scenes of the groundbreaking series that have both defined and changed the pop culture landscape.Honest, compelling and full of heart, Friday Night Lights brought small-town Texas football into the lives of television viewers across North America. From book to movie to the small screen, Friday Night Lights struggled against the odds to survive on television, finally doing so through an inno...

I've gotten used to living behind mirrors and smoke screens, it's easier to portray an image for the world to see. When I m alone I am haunted by my truth. A girl who entered this world in a jail cell. A girl who was served struggle with a side of pain on a broken platter. A girl who was thrown into a tank with sharks deep in a world whose motto is to eat or be eaten. I can still see the dirt underneath my nails; I've fought too hard to get where I am and I don t plan on looking back. How...