Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments rem...

Homeostasis of key metabolites and metabolic health affects all bodily systems. Not surprisingly, altered metabolic function is associated with a wide spectrum of dysfunctions in the central nervous system – including developmental disorders, acute nervous system injury, and neurodegenerative disorders. Accordingly, metabolism-based therapies offer significant promise as new category of treatment options designed to limit, delay or reverse the disease process by reconstructing homeostatic ...

An extraordinary memoir about the cutting-edge brain therapy that dramatically changed the life and mind of John Elder Robison, the New York Times bestselling author of Look Me in the EyeNAMED ONE OF THE BEST BOOKS OF THE YEAR BY THE WASHINGTON POSTImagine spending the first forty years of your life in darkness, blind to the emotions and social signals of other people. Then imagine that someone suddenly switch...

The perception-action cycle is the circular flow of information that takes place between the organism and its environment in the course of a sensory-guided sequence of behaviour towards a goal. Each action causes changes in the environment that are analyzed bottom-up through the perceptual hierarchy and lead to the processing of further action, top-down through the executive hierarchy, toward motor effectors. These actions cause new changes that are analyzed and lead to new action, and so ...

Positive, practical and realistic, this book offers a wealth of information on women, dating and relationships for men with Asperger Syndrome (AS).Many AS men are totally confused and bewildered by women and relationships and find it hard to know what to do, what to say and how to get it right. For these men, understanding the emotional side to relationships and women's needs can be a complete mystery and they often get it disastrously wrong. This practical handbook provides the an...

This book is a celebration of all the wonderful and unexpected gifts that having a daughter on the autism spectrum can bring to a family. Each chapter offers encouragement and guidance on issues such as school, friendships, meltdowns, special gifts, family relationships, therapies and interventions. Having daughters on the spectrum presents unique and rewarding challenges and this book is packed with friendly advice and real life examples from a mother who has experienced it all first hand...

This issue of Current Topics in Behavioral Neuroscience focuses on the neuropeptide orexin (hypocretin) and brings together scientists from around the world who will provide a timely discussion of how this peptide regulates behavior. This is a fast-moving field, and with the incorporation of novel technologies, new breakthroughs are likely to continue. For example, the use of optogenetic approaches has enabled the identification of the role of orexin-containing neurons in arousal ...

Brain, Part 1 of***The Netter Collection of Medical Illustrations:*Nervous System, 2nd Edition, provides a highly visual guide to this complex organ, from basic neurodevelopment, neuroanatomy, neurophysiology, and cognition to classic disorders including to epilepsy, hypothalamus/pituitary with disorders of consciousness and sleep, movement disorders, cerebellum, stroke, multiple sclerosis, neurologic inf...

An examination of brain-immune system communication in autism, schizophrenia, and depression.In Infectious Behavior, neurobiologist Paul Patterson examines the involvement of the immune system in autism, schizophrenia, and major depressive disorder. Although genetic approaches to these diseases have garnered the lion's share of publicity and funding, scientists are uncovering evidence of the important avenues of communication between the brain and the immu...

Intensive interaction is a valuable approach, with the potential to radically enhance the well-being of difficult-to-reach individuals, such as those with profound and severe learning disabilities, autistic spectrum conditions and emotional problems. This highly accessible book will help families and professionals develop a deeper understanding of this highly-successful approach and its associated issues, resulting in improved communication opportunities within a variety of care, therapeut...

This book is designed to introduce the reader to the field of NMR/MRI at very low magnetic fields, from milli-Tesla to micro-Tesla, the ultra-low field (ULF) regime. The book is focused on applications to imaging the human brain, and hardware methods primarily based upon pre-polarization methods and SQUID-based detection. The goal of the text is to provide insight and tools for the reader to better understand what applications are best served by ULF NMR/MRI approaches. A discussion of the ...

MATLAB for Neuroscientists: An Introduction to Scientific Computing in MATLAB is the first comprehensive teaching resource and textbook for the teaching of MATLAB in the Neurosciences and in Psychology. MATLAB is unique in that it can be used to learn the entire empirical and experimental process, including stimulus generation, experimental control, data collection, data analysis and modeling. Thus a wide variety of computational problems can be addressed in a single programming environmen...