The preparation of sterile products using aseptic processing is considered perhaps the most critical process in the pharmaceutical industry and has witnessed continual improvement over the last half century. New approaches that have transformed classical aseptic production methods are appearing almost daily. This book reviews emerging technologies for aseptic processing that will markedly reduce the level of contamination risk for sterile products and includes coverage on:The...

Rapid prototyping (RP) has revolutionized how prototypes are made and small batch manufacturing is carried out. With rapid prototyping, the strategies used to produce a part change a number of important considerations and limitations previously faced by tool designers and engineers. Now in its third edition, this textbook is still the definitive text on RP. It covers the key RP processes, the available models and specifications, and their principles, materials, advantages and disadvantages...

Additive Manufacturing (AM) technologies are developing impressively and are expected to bring about the next revolution. AM is gradually replacing traditional manufacturing methods in some applications because of its unique properties of customisability and versatility. This book provides a very comprehensive and updated text about different types of AM technologies, their respective advantages, shortcomings and potential applications.3D Printing and Additive Manufacturing: Principles and...

Digital Workflow in Reconstructive Dentistry is the result of efforts made by the academic team at the Department of Prosthodontics, University Hospital of Freiburg. It aims to build a fundamental understanding of the general principles, science, and clinics of digital dental medicine. The information provided within these pages summarizes the various components of the digital workflow in reconstructive dentistry and discusses their advantages and disadvantages. Moreover, insights are prov...

Essential information for architects, designers, engineers, equipment suppliers, and other professionals who are working in or entering the biopharmaceutical manufacturing fieldBiomanufacturing facilities that are designed and built today are radically different than in the past. The vital information and knowledge needed to design and construct these increasingly sophisticated biopharmaceutical manufacturing facilities is difficult to find in published literature—...

Proven and tested guidelines for designing ideal labs for scientific investigationsNow in its Fourth Edition, Guidelines for Laboratory Design continues to enable readers to design labs that make it possible to conduct scientific investigations in a safe and healthy environment. The book brings together all the professionals who are critical to a successful lab design, discussing the roles of architects, engineers, health and safety professionals, and labo...

This revised publication serves as a handy and current reference for professionals engaged in planning, designing, building, validating and maintaining modern cGMP pharmaceutical manufacturing facilities in the U.S. and internationally. The new edition expands on facility planning, with a focus on the ever-growing need to modify existing legacy facilities, and on current trends in pharmaceutical manufacturing which include strategies for sustainability and LEED building ratings. All chapte...

This key document, produced by the BFS IOA, outlines important aspects on operation of BFS technology to ensure both compliance with cGMP regulations and the production of drug products of the appropriate quality, safety and efficacy. The Points to Consider document provides recommendations specific to the operation of Blow-Fill-Seal technology for the manufacture of sterile pharmaceuticals and liquid medical devices. One of the aims of this document is to define the minimum standards expe...

A valuable and comprehensive safety reference for any organization working with or around electricity.This comprehensive guide informs working professionals in multiple industries, such as manufacturing, processing, or energy, about safety procedures that should be used on the job. It informs the reader about the hazards in the work place and what to do to make sure he/she is protected.The Handbook of International Electrical Safety Practices prese...

This open access book gives both a theoretical and practical overview of several important aspects of additive manufacturing (AM). It is written in an educative style to enable the reader to understand and apply the material. It begins with an introduction to AM technologies and the general workflow, as well as an overview of the current standards within AM. In the following chapter, a more in-depth description is given of design optimization and simulation for AM in polymers and metals, i...

Since its recognition as the first specialty of dentistry, the practice of orthodontics has been influenced by the development of new materials, techniques, bracket designs and prescriptions, appliances, and software. However, never before has there been as revolutionary a change as digitization. Digitization and automation are transforming the entire landscape of how orthodontics is practiced, and the consequence is the "do it yourself" concept. With the technology available today with in...

Research institutions have or are planning to build, expand and renovate animal research facilities to keep up with the demands of biomedical research caused in part by growth in the use of genetically altered rodents and the upsurge of research in infectious diseases. Properly designed facilities greatly facilitate effective management and high-quality day-to-day animal care that is required to optimally support animal research and testing. There are multiple solutions to address the myri...