Over the past years, a considerable amount of effort has been devoted, both in industry and academia, towards the development of basic technology as well as innovative applications for the Internet of Things. Adaptive Middleware for the Internet of Things introduces a scalable, interoperable and privacy-preserving approach to realize IoT applications and discusses abstractions and mechanisms at the middleware level that simplify the realization of services that can adapt autonomously to th...

Winner of the 2023 PROSE award in Biomedicine and Neuroscience! Research in the field of senescence has boomed recently due to the gradual realization that senescent cells are associated with a significant number of diseases. The genetic or pharmacological elimination of senescent cells can cause widespread benefits and improves outcomes for most of those diseases. Cellular Senescence in Diseases presents an updated review of the role of cellular senescence in multiple pathologies. Focus i...

- El síndrome metabólico es uno de los retos más intrigantes y fascinantes de la medicina contemporánea. Se trata de una patología en la que confluyen problemas de distintas áreas de la medicina: diferentes grados de hipertensión, acumulación de grasa, insulinoresistencia, estados protrombótico y proinflamatorio, todos juntos en la misma persona. Esta concurrencia de factores hace que la persona tenga un riesgo mucho mayor de sufrir enfermedad cardiovascular o diabetes mellitus tipo 2, que...

Obesity is the second volume in a four-title series, along with Type 2 Diabetes Mellitus (T2D), Arterial Hypertension, and Atherogenic dyslipidemia. It covers every major aspect of obesity from a multidisciplinary approach, thanks to collaborative efforts of a select team of international, world-reknowned experts. It offers updated information on a wide variety of topics, ranging from the general to the specific. These include the pathophysiology of obesity; the influence of social, demogr...

This book constitutes the thoroughly refereed revised selected papers of the 16th International Symposium on Trends in Functional Programming, TFP 2015, held in Sophia Antipolis, France, in June 2015. The 8 revised full papers included in this volume were carefully and selected from 26 submissions. TFP is an international forum for researchers with interests in all aspects of functional programming, taking a broad view of current and future trends in the area. It aspires to be a lively env...

Over the past years, a considerable amount of effort has been devoted, both in industry and academia, towards the development of basic technology as well as innovative applications for the Internet of Things. Adaptive Middleware for the Internet of Things introduces a scalable, interoperable and privacy-preserving approach to realize IoT applications and discusses abstractions and mechanisms at the middleware level that simplify the realization of services that can adapt autonomously to th...

A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook providessystematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviewsthe main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the threemain classes of xenobiotics: drugs, natural products, environment...

**Selected for Doody's Core Titles® 2024 in Nutrition**Ketogenic: The Science of Therapeutic Carbohydrate Restriction in Human Health presents the most up-to-date and evidence-based science and research available in the field of TCR, with the purpose of training medical and allied healthcare professionals on the effective therapeutic use of low-carbohydrate and ketogenic nutrition in clinical practice. This book explores the appropriate, safe, and effective use of TCR to improve patient ou...

METABOLIC SYNDROMEA comprehensive look at the fight against the metabolic syndrome epidemicIncreasing risk of cardiovascular disease and diabetes, the metabolic syndrome is a world health problem that demands attention from all levels of the health care industry. Metabolic Syndrome: Underlying Mechanisms and Drug therapies extensively covers the metabolic syndrome with an emphasis on drug discovery efforts, providing a context of m...

Awareness of the influence of our genetic variation to dietary response (nutrigenetics) and how nutrients may affect gene expression (nutrigenomics) is prompting a revolution in the field of nutrition. Nutrigenetics/Nutrigenomics provide powerful approaches to unravel the complex relationships among nutritional molecules, genetic variants and the biological system. This publication contains selected papers from the ‘3rd Congress of the International Society of Nutrigenetics/Nutrigenomics’ ...

“Drs. Butterfield, Kaufman and Marincola on behalf of the SITC have created a comprehensive must-have resource covering the basic and translational science behind approved and investigational immune therapies, and disease-by-disease clinical application of the therapies, written by leaders in the field. The textbook will be highly valuable reading for those just entering the field and for experienced scientists and clinicians looking to expand their knowledge base.”—Mario ...

The book provides a comprehensive overview to understanding the integrated impact of the concepts of cellular and molecular aspects, models, environmental factors, and lifestyle involved in premature aging. Additionally, it examines how functional food, dietary nutraceuticals or pharmacological compounds can reverse inflammation and premature aging based on personalized medicine. This book is a valuable resource for health professionals, scientists and researchers, nutritionists, health pr...