It’s his birthday, and Jimmy gets to pick out a dog at the humane society. Jimmy has wanted a dog for as long as he can remember. But he never imagined he’d find a pet that could talk to him telepathically!It turns out that the dog is immortal, born in Egypt more than three thousand years ago. With the ability to read both canine and human thoughts, he has roamed the earth ever since, hoping to find others of his kind. Only after he meets Jimmy does he begin to discover clues to hi...

American Stonehenge is the first book in the new series The Adventures of Jimmy and Andrew. Secrets to some of our world's most ancient and mysterious legends are revealed to our two heroes in their first epic adventure.Age Level: 9 and up | Grade Level: 4 and upIt's his birthday, and Jimmy gets to pick out a dog at the humane society. Jimmy has wanted a dog his whole life. But he never imagined he'd find a pet that could talk to him telepathically!It turns out that...

This volume focuses on translational models of pediatric brain cancers that are critical to understanding tumor formation, tumor progression, and response to treatment. These models are particularly important for drug screens and preclinical testing of novel treatment approaches involving chemotherapy, radiation, and immunotherapy. The chapters in this book cover a variety of the latest technologies used to investigate the molecular backbone of pediatric brain tumors. These new diagnostic ...

This book focuses on the modelling of contemporary health and social problems, especially those considered a major burden to communities, governments and taxpayers, such as smoking, alcoholism, drug use, and heart disease. Based on a series of papers presented at a recent conference hosted by the Leverhulme-funded Tipping Points project at the University of Durham, this book illustrates a broad range of modelling approaches. Such a diverse collection demonstrates that an interdisciplinary ...

Jacob (‘Jack’) Goldstein was mid-upper gunner in a Lancaster bomber when it was shot down by a German night-fighter during Bomber Command’s final WW2 mission to Nürnberg. It was the night of 16 March 1945, just a few weeks before the war ended. He was the only member of the seven-man crew to be killed. The title of the book derives from the simple entry ‘Shalom!’ that Jack’s widow, Sadie, poignantly wrote in the book of remembrance at the Dürnbach War Graves Cemetery where Jack is now buri...

Master ethical leadership and high-stakes negotiation by applying ancient diplomatic strategies to modern conflicts. Whether you are navigating workplace politics during your commute or preparing to mediate a boardroom dispute, these tactics provide a distinct competitive advantage. Transform historical resilience into actionable corporate influence.For centuries, minority communities relied on strategic coalition building and empathy to thrive against overwhelming odds. Harness th...

The need for novel antibiotics is greater now than perhaps any time since the pre-antibiotic era. Indeed, the recent collapse of many pharmaceutical antibacterial groups, combined with the emergence of hypervirulent and pan-antibiotic-resistant bacteria has severely compromised infection treatment options and led to dramatic increases in the incidence and severity of bacterial infections.This collection of reviews and laboratory protocols gives the reader an introduction to the cau...

A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of t...

The Tohoku University Graduate School of Dentistry first introduced the concept of “Interface Oral Health Science”, designed to establish and maintain healthy oral cavities, which are home to a number of mixed systems. Included in those systems are: (1) host tissues such as teeth, mucosa, muscle and bone, (2) parasites and microorganisms cohabiting the surfaces of the oral cavity and (3) biomaterials that are used for the rehabilitation of oral functions. In addition, (4) these systems are...

Organs and Mini-Organs combines contributions from leading practitioners who work under the editorial control of an acclaimed researcher who also served for eight years as Editor-in-Chief of the journal Organogenesis, the first journal on this topic. The book begins with an introduction, but then delves into chapters that present advice on how to make organoids for many systems. In addition, case studies that illustrate the uses of organioids are presented, along with discussions on future...

Unique coverage of proteomic and glycomic approaches to better distinguish highly dangerous pathogens, as well as using these to explore novel treatment and prevention options.The editors and authors are either part of a specialized European network initiated to develop fast and reliable detection and therapy options, or are associated with the core military research complex of the United States.With its description of the methods, their advantages and limitations, as well as...

How stem cells behave is very much a factor of their local microenvironment, also known as the stem cell niche. Physical, chemical, or electrical signals from the neighboring cells or biochemical signals from distant cells are crucial in the cell fate decision process. A major challenge of tissue engineering is to mimic the natural cell environment by designing very sophisticated scaffolds able not only to mechanically support cells, but also to release signals biologically relevant for go...