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Springer Protocols eBook Series

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  • Targeting Enzymes for Pharmaceutical Development

    Methods and Protocols

    Edited by Nikolaos Labrou ...
    Series series Springer Protocols
    This second edition volume expands on the previous edition with a discussion of the latest experimental and computational strategies used in the study, characterization, and targeting of enzymes with therapeutic potential. The chapters in the book are organized into two parts: Part One presents detailed, reproducible protocols for enzyme characterization, inhibitor screening, and biochemical ... Read more

    $204.99 CAD

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  • Applied Computer-Aided Drug Design: Models and Methods

    by Igor José dos Santos Nascimento ...
    Designing and developing new drugs is an expensive and time-consuming process, and there is a need to discover new tools or approaches that can optimize this process. Applied Computer-Aided Drug Design: Models and Methods compiles information about the main advances in computational tools for discovering new drugs in a simple and accessible language for academic students to early career ... Read more

    $75.89 CAD

  • Mass Spectrometry-Based Proteomics

    Edited by Kris Gevaert ...
    Series series Springer Protocols
    This detailed volume explores contemporary techniques in mass spectrometry-based proteomics. After covering overall proteome coverage and the cellular surfaceome, the book delves into proximity-induced biotinylation, abduction of protein complexes in viral-like particles, and thermal proteome profiling, as well as protocols for identifying protein N-terminal acetylation, protein processing by ... Read more

    $215.99 CAD

  • Computer Aided Drug Design (CADD): From Ligand-Based Methods to Structure-Based Approaches

    Edited by Mithun Rudrapal, Chukwuebuka Egbuna ...
    Series series Drug Discovery Update
    Computer-Aided Drug Design (CADD): From Ligand-Based Methods to Structure-Based Approaches outlines the basic theoretical principles, methodologies and applications of different fundamental and advanced CADD approaches and techniques. Including information on current protocols as well as recent developments in the computational methods, tools and techniques used for rational drug design, the book ... Read more

    $199.19 CAD

  • IMMUNO-model in Cancer

    Methods and Protocols

    Edited by Sweta Rani, Lukasz Skalniak ...
    Series series Springer Protocols
    This open access volume describes the computational and experimental models that help researchers understand the responses of the immune system in cancer and test experimental immune-oncology approaches. The chapters in this book cover methods such as profile polarization in macrophages using ELISA; immune checkpoint inhibitors; interactions of PD-1/PD-L1 and T cells; immunocompetent preclinical ... Read more

    Free

  • Clinical Metabolomics

    Methods and Protocols

    Edited by Martin Giera, Elena Sánchez-López ...
    Series series Springer Protocols
    This second edition volume presents new and updated protocols on comprehensive compendium of clinical metabolomics protocols covering LC-MS, GC-MS, CE-MS, and NMR-based clinical metabolomics as well as bioinformatics and study design considerations. Chapters explore the core of several promising initiatives evolving around personalized health care and precision medicine. Written for the highly ... Read more

    $230.99 CAD

  • Transketolases

    by Franck Charmantray, Bastien Doumèche ...
    Series Book 722 - Methods in Enzymology
    Transketolase, Volume 724 in the Methods in Enzymology series, is devoted to the description of cutting-edge methods to its study in biochemistry. Chapters in this new release include Role of transketolase-like 1 in human cortical neurogenesis, Transketolase in metabolic diseases, autoimmune diseases and cancer, Transketolase-like-1 (TKTL1) based one-substrate reaction and its impact on ... Read more

    $175.99 CAD

  • Lipids and Membranes: Detection by Imaging and Lipidomics

    by Jeremy M. Baskin ...
    Series Book 726 - Methods in Enzymology
    Lipids and Membranes: Detection by Imaging and Lipidomics, Volume 727 covers lipids, a chemically diverse set of biological molecules subject to rapid metabolism and transport. This dynamic behavior has motivated the development of methods across multiple disciplines for their detection and manipulation. Split into three parts, the chapters in this new release include Measurement of fatty acid ... Read more

    $216.99 CAD

  • Modern Proteomics – Sample Preparation, Analysis and Practical Applications

    Edited by Hamid Mirzaei, Martin Carrasco ...
    Series series Biomedical and Life Sciences (R0)
    This volume serves as a proteomics reference manual, describing experimental design and execution. The book also shows a large number of examples as to what can be achieved using proteomics techniques. As a relatively young area of scientific research, the breadth and depth of the current state of the art in proteomics might not be obvious to all potential users. There are various books and review ... Read more

    $192.99 CAD

  • Mass Spectrometry Based Single Cell Proteomics

    Edited by Akos Vegvari, Jaakko Teppo, Roman A. Zubarev ...
    Series series Springer Protocols
    This volume explores the latest advancements made in the field of mass spectrometry (MS) based single cell proteomics. The chapters in this book focus on technologies, methods, and biological applications and together cover the entire single cell proteomics analysis workflow, from sample collection and preparation through liquid chromatographic separation and mass spectrometric data acquisition to ... Read more

    $166.99 CAD

  • SH2 Domains

    Functional Modules and Evolving Tools in Biology

    Edited by Teresa Carlomagno, Maja Köhn ...
    Series series Springer Protocols
    This volume looks at the latest methods used to study and modulate the biological function and mechanisms of SH2 domains. The chapters in this book are organized into five parts. Part One presents methodology aimed at determining the structures and dynamics of SH2 domains and their complexes with phosphopeptides. Part Two discusses techniques to understand and predict interactions of SH2 domains ... Read more

    $215.99 CAD

  • Protein Termini Part B

    by David Christianson, Karen N. Allen, Thomas Arnesen ...
    Series Book 719 - Methods in Enzymology
    Protein termini represent a major route to protein regulation. From the moment the very first amino acid of a polypeptide chain exits the ribosome there is potential for steering from the cellular environment. This volume of Methods in Enzymology Modifications and Targeting of Protein Termini focuses on Protein N-termini and C-termini and their modifications which include acetylation, arginylation ... Read more

    $216.79 CAD