From the acclaimed author of Miracle Cure and The Third Horseman, the epic story of the collision between one of nature's smallest organisms and history's mightiest empireDuring the golden age of the Roman Empire, Emperor Justinian reigned over a territory that stretched from Italy to North Africa. It was the zenith of his achievements and the last of them. In 542 AD, the bubonic plague struck. In weeks, the glorious classical world of Justinian h...

The Emperor Justinian reunified Rome's fractured empire by defeating the Goths and Vandals who had separated Italy, Spain, and North Africa from imperial rule. At his capital in Constantinople, he built the world's most beautiful building, married its most powerful empress, and wrote its most enduring legal code, seemingly restoring Rome's fortunes for the next 500 years. Then, in the summer of 542, he encountered a flea. The ensuing outbreak of bubonic plague killed 5,000 people a day in ...