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Springer Protocols Série de Livres électroniques

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  • Exon Skipping and Inclusion Therapies

    Methods and Protocols

    Modifié par Yusuke Echigoya, Rika Maruyama, Toshifumi Yokota ...
    Collections series Springer Protocols
    This fully updated edition presents a collection of protocols reflecting the latest advancements in exon skipping and inclusion strategies. The book explores the design of antisense oligonucleotide therapies, in vitro and in vivo evaluation of exon skipping in Duchenne muscular dystrophy, enhancing exon skipping efficiency, as well as methods involving spinal muscular atrophy and other diseases. ... En savoir plus

    $217.79 CAD

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  • Antibiotics

    Targets, Mechanisms and Resistance

    Modifié par Claudio O. Gualerzi, Letizia Brandi, Attilio Fabbretti, Cynthia L. Pon ...
    Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly needed.Opening with a general introduction about antimicrobial drugs, their targets and the problem of antibiotic ... En savoir plus

    $205.99 CAD

  • Translational Medicine

    Molecular Pharmacology and Drug Discovery

    Modifié par Robert A. Meyers ...
    Collections series Advances in Molecular Biology and Medicine
    This reference work gives a compete overview of the different stages of drug development using a translational approach. The book is structured in different parts, following the different stages in drug development. Almost half of the work is dedicated to core of drug discovery using a translational approach, the identification of appropriate targets and screening methods for the identification of ... En savoir plus

    $480.99 CAD

  • Handbook of Glycomics

    Modifié par Richard D. Cummings, J. Michael Pierce ...
    The Handbook of Glycomics provides the first comprehensive overview of the emerging field of glycomics, defined as the study of all complex carbohydrates in an organism or cell ("the glycome"). Beginning with analytic approaches and bioinformatics, this work provides a detailed discussion of relevant databases, data integration, and analysis. It then moves on to a discussion of specific model ... En savoir plus

    $89.99 CAD

  • Drug Discovery Stories, Volume 2

    Modifié par Bin Yu, Peng Zhan ...
    Drug Discovery Stories, Volume Two showcases the discovery journeys of recent blockbuster drugs approved between 2023 and 2024, along with promising drug candidates. This book delves into structural biology, biological functions of targets, hit compound identification, hit-to-lead optimization, binding modes, key biological and pharmacokinetic data, and clinical results. It also covers other ... En savoir plus

    $219.99 CAD

  • Chemistry and Pharmacology of Drug Discovery

    Modifié par Jie Jack Li ...
    Case studies of 20 successful FDA-approved drugs, from biological rationale to clinical efficacy studies and state-of-the-art applicationsChemistry and Pharmacology of Drug Discovery illustrates how chemistry, biology, pharmacokinetics, and a host of disciplines come together to produce successful medicines, discussing a total of 20 drugs that are all FDA-approved post 2021—some of which are first ... En savoir plus

    $203.99 CAD

  • Protein Therapeutics

    par Raimund Mannhold, Gerd Folkers, Helmut Buschmann ...
    Collections series Methods & Principles in Medicinal Chemistry
    In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades.Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, ... En savoir plus

    $338.99 CAD

  • Principles and Applications of Molecular Diagnostics

    Modifié par A. Rita Horvath, Carl T. Wittwer, Jason Park, Nader Rifai ...
    Principles and Applications of Molecular Diagnostics serves as a comprehensive guide for clinical laboratory professionals applying molecular technology to clinical diagnosis. The first half of the book covers principles and analytical concepts in molecular diagnostics such as genomes and variants, nucleic acids isolation and amplification methods, and measurement techniques, circulating tumor ... En savoir plus

    $106.99 CAD

  • Autophagy in Disease and Clinical Applications, Part C

    Modifié par Daniel Klionsky ...
    Collections Livre 453 - Methods in Enzymology
    The third and final installment of Daniel J. Klionsky's new three-volume treatment of autophagy, this volume focuses on monitoring autophagy with regard to disease connections, and presents methods that can be used to analyze autophagy in clinical samples. Edited by one of the leading authorities in the field, this volume and its companion volumes, Autophagy: Lower Eukaryotes and Autophagy in ... En savoir plus

    $170.99 CAD

  • Bispecific Antibodies

    Methods and Protocols

    Modifié par Masahiro Yasunaga ...
    Collections series Springer Protocols
    This volume explores protocols and perspectives for the design, production, characterization, functional evaluation, and clinical translation of bispecific antibodies (BsAbs). Beginning with a variety of platforms for generating BsAbs, the book continues with sections covering protocols to evaluate T-cell-dependent bispecific antibodies, modeling and simulation approaches to support clinical ... En savoir plus

    $230.59 CAD

  • Advances in Clinical Chemistry

    par Gregory S. Makowski ...
    Collections Livre 128 - Advances in Clinical Chemistry
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. - Provides the latest information on Clinical Chemistry - Offers outstanding and original reviews on a range of Clinical Chemistry research topics - Serves as an indispensable reference for researchers and ... En savoir plus

    $181.99 CAD

  • Tumor Immunology and Immunotherapy – Cellular Methods Part A

    par Lorenzo Galluzzi, Nils-Petter Rudqvist ...
    Collections Livre 631 - Methods in Enzymology
    Tumor Immunology and Immunotherapy – Cellular Methods Part A, Volume 631, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. New chapters include Detection of intracellular cytokine production by T cells with flow cytometry, High-throughput identification of human antigen-specific CD8+ and CD4+ ... En savoir plus

    $175.99 CAD