Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As ...

Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a c...

Featuring stunning illustrations, this compact volume explores the early successes of the aircraft model and its aces.Although only built in modest numbers principally for the Dutch Air Force, the low-cost monoplane D.XXI fighter enjoyed its greatest success in combat with the Finnish Air Force. The Dutch D.XXIs saw less than a week of action following the German invasion of the west on 10 May 1940, with many of the country's 28 fighters being destroyed on the grou...

A dynamic remastering of the original BBC Radio 4 full-cast serial - Fit the First to Fit the Sixth - which spawned a phenomenal hitchhiking legendThe original series of The Hitchhiker's Guide to the Galaxy, remastered by Dirk Maggs (director of the Tertiary, Quandary and Quintessential Phases) to give a full, vibrant sound, now with Philip Pope's version of the familiar theme tune and specially re-recorded announcements by John Marsh.Join Arthur D...

An illustrated history of a remarkable aircraft, the Dornier Do 24, which served both military and humanitarian purposes.Perhaps the most seaworthy flying boat ever built, the elegant, tri-motor Dornier Do 24 served with both the Allied and Axis forces in very different parts of the globe during World War 2, garnering an excellent reputation along the way. This study uses archival records, first-hand accounts and revealing photographs to illuminate the combat caree...

An illustrated history of a remarkable aircraft, the Dornier Do 24, which served both military and humanitarian purposes.Perhaps the most seaworthy flying boat ever built, the elegant, tri-motor Dornier Do 24 served with both the Allied and Axis forces in very different parts of the globe during World War 2, garnering an excellent reputation along the way. This study uses archival records, first-hand accounts and revealing photographs to illuminate the combat caree...

Featuring stunning illustrations, this compact volume explores the early successes of the aircraft model and its aces.Although only built in modest numbers principally for the Dutch Air Force, the low-cost monoplane D.XXI fighter enjoyed its greatest success in combat with the Finnish Air Force. The Dutch D.XXIs saw less than a week of action following the German invasion of the west on 10 May 1940, with many of the country's 28 fighters being destroyed on the grou...

Ralph sat up. His voice was croaky. ‘If a shooting star zoomed past right now, what would you wish for?’ ‘To find another friend like you.’ Leo and Ralph have been best friends ever since Ralph flew down from one of Jupiter's moons. But now Leo's older, and Mum and Dad think it’s time to say goodbye to Ralph. When the family moves to a small country town, they hope Leo might finally make a real friend. But someone like Ralph is hard to leave behind ...

Don’t Panic! Reissued for the first time in 40 years, two unique recordings of Douglas Adams's sci-fi comedy drama.When Earthman Arthur Dent learns that first his house and then his planet are about to be bulldozed, it’s the beginning of an interplanetary adventure for him and his friend, Ford Prefect. After fleeing Earth they hitch a lift with hoopy frood Zaphod Beeblebrox, who hurtles from one improbability to another - literally. With Trillian and Marvin the Paranoid Android in ...

A dynamic remastering of the second BBC Radio 4 full-cast serial – Fit the Seventh to Fit the Twelfth – which spawned a phenomenal hitchhiking legendThe second original series of The Hitchhiker’s Guide to the Galaxy remastered by Dirk Maggs (director of the Tertiary, Quandary and Quintessential Phases) to give a full, vibrant sound, now with Philip Pope’s version of the familiar theme tune and specially re-recorded announcements by John Marsh.Stran...

Davey is Peter's older brother. Davey is head strong and if he wants something, he'll do what it takes to get it, as long as it doesn't mean being good. Peter is shy and looks up to his big brother and gets carried along in some of Davey's antics. They both enjoy charging around and play fighting. Davey has conflicts with his cousin Justine, who herself is head strong, but mardy. Mum finds dealing with the boys a handful as Dad works long hours and isn't around a lot.

Bob Evers reisde, eind jaren veertig, voor de eerste keer in zijn leven naar Nederland, een paar weken voor hij samen met Jan Prins en Arie Roos aan boord stapte van het vrachtschip Esperanza. 'Met als eerste haven van bestemming Buenos Aires ... en daarna? Wilde vaart!' Zo staat het in 'Avonturen in de Stille Zuidzee' en liefhebbers van de serie vragen zich natuurlijk al meer dan zeventig jaar lang af hoe het toch komt dat Jan, Bob en Arie vanaf de eerste dag de dikste vrienden bleken. He...