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  • Difference Gel Electrophoresis

    Methods and Protocols

    Redigeret af Kay Ohlendieck ...
    Serier serie Springer Protocols
    The second edition of this volume provides a comprehensive update of this key method on gel-based proteomics. Chapters present an introduction into the development of methods on principles of differential protein labeling and two-dimensional gel electrophoresis, techniques on optimized proteomic workflows using advanced mass spectrometry for protein identification, and the application of those ... Læs mere

    1.400,85 kr.

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  • Antigen Retrieval Immunohistochemistry Based Research and Diagnostics

    Redigeret af Shan-Rong Shi, Clive R. Taylor ...
    Serier Bog 5 - Wiley Series in Biomedical Engineering and Multi-Disciplinary Integrated Systems
    The most complete, up-to-date reference on antigen retrieval and immunohistochemistryAn antigen is a substance that prompts the generation of antibodies and can cause an immune response. The antigen retrieval (AR) technique is in wide use across the globe, and is a critical technique used in medical diagnosis of disease, particularly clinical targeted cancer treatment.Antigen Retrieval ... Læs mere

    1.302,61 kr.

  • BSL3 and BSL4 Agents

    Proteomics, Glycomics and Antigenicity

    Unique coverage of proteomic and glycomic approaches to better distinguish highly dangerous pathogens, as well as using these to explore novel treatment and prevention options.The editors and authors are either part of a specialized European network initiated to develop fast and reliable detection and therapy options, or are associated with the core military research complex of the United States ... Læs mere

    814,86 kr.

  • Antibody Engineering Volume 1

    Serier serie Springer Protocols
    Antibodies are indispensable tools for research, diagnosis, and therapy. Recombinant approaches allow the modification and improvement of nearly all antibody properties, such as affinity, valency, specificity, stability, serum half-life, effector functions, and immunogenicity. "Antibody Engineering" provides a comprehensive toolbox covering the well-established basics but also many exciting new ... Læs mere

    3.166,13 kr.

  • In Vitro Bioassay Techniques for Anticancer Drug Discovery and Development

    This comprehensive and useful handbook represents a definitive up-to-date compendium of key in vitro bioassay methods that are employed to quantify and validate the anticancer activity of a drug candidate before it makes its way in to animal or clinical trials.In Vitro Bioassay Techniques for Anticancer Drug Discovery and Development covers the screening and evaluation of potential drug candidates ... Læs mere

    439,78 kr.

  • Translational Medicine

    Molecular Pharmacology and Drug Discovery

    Redigeret af Robert A. Meyers ...
    Serier serie Advances in Molecular Biology and Medicine
    This reference work gives a compete overview of the different stages of drug development using a translational approach. The book is structured in different parts, following the different stages in drug development. Almost half of the work is dedicated to core of drug discovery using a translational approach, the identification of appropriate targets and screening methods for the identification of ... Læs mere

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  • Current Trends in Monoclonal Antibody Development and Manufacturing

    Serier serie Biomedical and Life Sciences (R0)
    Monoclonal antibodies represent one of the fastest growing areas of new drug development within the pharmaceutical industry. Several blockbuster products have been approved over the past several years including Rituxan, Remicade, Avastin, Humira, and Herceptin. In addition, over 300 new drugs are currently in clinical trials. With both large, established biotechnology companies and small start-ups ... Læs mere

    1.867,83 kr.

  • Capillary Electrophoresis of Carbohydrates

    From Monosaccharides to Complex Polysaccharides

    Redigeret af Nicola Volpi ...
    Simple carbohydrates, complex oligosaccharides and polysaccharides all belong to a class of ubiquitous (macro)molecules that exhibit a wide range of biological functions, and the recent advent of enhanced enzymatic, chemical and analytical tools used to study these sugars has inaugurated a genuine explosion in the field of glycomics. Specifically, it has led to a deeper understanding of how ... Læs mere

    840,49 kr.

  • Sample Preparation in Biological Mass Spectrometry

    Serier serie Chemistry and Material Science (R0)
    The aim of this book is to provide the researcher with important sample preparation strategies in a wide variety of analyte molecules, specimens, methods, and biological applications requiring mass spectrometric analysis as a detection end-point. In this volume we have compiled the contributions from several laboratories which are employing mass spectrometry for biological analysis. With the ... Læs mere

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  • Proteoglycans

    Methods and Protocols

    Redigeret af Nikos K. Karamanos ...
    Serier serie Springer Protocols
    This volume is acomprehensive and up-to-date collection of strategies, reproducible methods, and protocols for the in-depth analysis of Proteoglycans (PGs) and their glycan part, the GAGs. Chapters are divided into three parts detailing GAGs in biological specimens, protocols for the evaluation of the in vitro and in vivo effects of PGs/GAGs, and protocols for compounds related with the metabolic ... Læs mere

    1.134,67 kr.

  • The Protein Protocols Handbook

    Redigeret af John M. Walker ...
    Serier serie Springer Protocols
    The Protein Protocols Handbook, Second Edition aims to provide a cross-section of analytical techniques commonly used for proteins and peptides, thus providing a benchtop manual and guide for those who are new to the protein chemistry laboratory and for those more established workers who wish to use a technique for the first time. All chapters are written in the same format as that used in the ... Læs mere

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  • Proximity Labeling

    Methods and Protocols

    Redigeret af Murat Sunbul, Andres Jäschke ...
    Serier serie Springer Protocols
    This book provides detailed protocols and untold tips and tricks regarding the most well-known examples of proximity labeling methods, in which the protein of interest is genetically fused to or labeled with an enzyme that can generate short-lived reactive species to non-specifically label molecules within a certain radius of up to twenty nanometers. Beginning with peroxidase-based proximity ... Læs mere

    1.120,66 kr.