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Springer Protocols Bogserier

1 - 12 af 12 resultater
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  • Clinical Metabolomics

    Methods and Protocols

    Redigeret af Martin Giera, Elena Sánchez-López ...
    Serier serie Springer Protocols
    This second edition volume presents new and updated protocols on comprehensive compendium of clinical metabolomics protocols covering LC-MS, GC-MS, CE-MS, and NMR-based clinical metabolomics as well as bioinformatics and study design considerations. Chapters explore the core of several promising initiatives evolving around personalized health care and precision medicine. Written for the highly ... Læs mere

    1.681,95 kr.

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  • Peptide Therapeutics

    Strategy and Tactics for Chemistry, Manufacturing, and Controls

    Redigeret af Ved Srivastava ...
    Serier Bog 72 - Drug Discovery Series
    Peptide therapy has become a key strategy in innovative drug development, however, one of the potential barriers for the development of novel peptide drugs in the clinic is their deficiencies in clearly defined chemistry, manufacturing and controls (CMC) strategy from clinical development to commercialization. CMC can often become a rate-limiting step due to lack of knowledge and lack of a formal ... Læs mere

    2.050,61 kr.

  • Ultra-High Performance Liquid Chromatography and Its Applications

    af Q. Alan Xu ...
    Explores both the benefits and limitations of new UHPLC technologyHigh performance liquid chromatography (HPLC) has been widely used in analytical chemistry and biochemistry to separate, identify, and quantify compounds for decades. The science of liquid chromatography, however, was revolutionized a few years ago with the advent of ultra-high performance liquid chromatography (UHPLC), which made ... Læs mere

    954,86 kr.

  • Handbook of LC-MS Bioanalysis

    Best Practices, Experimental Protocols, and Regulations

    Redigeret af Wenkui Li, Jie Zhang, Francis L. S. Tse ...
    Consolidates the information LC-MS bioanalytical scientists need to analyze small molecules and macromoleculesThe field of bioanalysis has advanced rapidly, propelled by new approaches for developing bioanalytical methods, new liquid chromatographic (LC) techniques, and new mass spectrometric (MS) instruments. Moreover, there are a host of guidelines and regulations designed to ensure the quality ... Læs mere

    1.233,74 kr.

  • Applied Computer-Aided Drug Design: Models and Methods

    af Igor José dos Santos Nascimento ...
    Designing and developing new drugs is an expensive and time-consuming process, and there is a need to discover new tools or approaches that can optimize this process. Applied Computer-Aided Drug Design: Models and Methods compiles information about the main advances in computational tools for discovering new drugs in a simple and accessible language for academic students to early career ... Læs mere

    384,86 kr.

  • Analytical Characterization of Biotherapeutics

    Redigeret af Jennie R. Lill, Wendy Sandoval ...
    The definitive guide to the myriad analytical techniques available to scientists involved in biotherapeutics researchAnalytical Characterization of Biotherapeutics covers all current and emerging analytical tools and techniques used for the characterization of therapeutic proteins and antigen reagents. From basic recombinant antigen and antibody characterization, to complex analyses for ... Læs mere

    1.498,74 kr.

  • Protein and Peptide Mass Spectrometry in Drug Discovery

    Redigeret af Michael L. Gross, Guodong Chen, Birendra Pramanik ...
    The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discoveryAn instrumental analytical method for quantifying the mass and characterization of various samples from small molecules to large proteins, mass spectrometry (MS) has become one of the most widely used techniques for studying proteins and peptides over the last decade. Bringing ... Læs mere

    1.254,74 kr.

  • Pharmaceutical Stress Testing

    Predicting Drug Degradation, Second Edition

    Redigeret af Steven W. Baertschi, Karen M. Alsante, Robert A. Reed ...
    Serier serie Drugs and the Pharmaceutical Sciences
    The second edition of Pharmaceutical Stress Testing: Predicting Drug Degradation provides a practical and scientific guide to designing, executing and interpreting stress testing studies for drug substance and drug product. This is the only guide available to tackle this subject in-depth. The Second Edition expands coverage from chemical stability ... Læs mere

    554,19 kr.

  • Absorption and Drug Development

    Solubility, Permeability, and Charge State

    af Alex Avdeef ...
    Explains how to perform and analyze the results of the latest physicochemical methodsWith this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and their effects on drug absorption. The book emphasizes oral absorption, explaining all the physicochemical methods used today to ... Læs mere

    1.324,36 kr.

  • Mass Spectrometry-Based Proteomics

    Redigeret af Kris Gevaert ...
    Serier serie Springer Protocols
    This detailed volume explores contemporary techniques in mass spectrometry-based proteomics. After covering overall proteome coverage and the cellular surfaceome, the book delves into proximity-induced biotinylation, abduction of protein complexes in viral-like particles, and thermal proteome profiling, as well as protocols for identifying protein N-terminal acetylation, protein processing by ... Læs mere

    1.571,96 kr.

  • Separation Techniques Applied to Omics Sciences

    From Principles to Relevant Applications

    Redigeret af Ana Valéria Colnaghi Simionato ...
    Serier serie Biomedical and Life Sciences (R0)
    This book covers liquid chromatography, gas chromatography and capillary electrophoresis, the three main separation techniques lately available, applied to key omic sciences, such as genomics, proteomics, metabolomics and foodomics. The fundamentals of each technique are not covered herein. Instead, the recent advances in such techniques are presented focusing on the application to omics analyses ... Læs mere

    1.588,50 kr.

  • Targeting Enzymes for Pharmaceutical Development

    Methods and Protocols

    Redigeret af Nikolaos Labrou ...
    Serier serie Springer Protocols
    This second edition volume expands on the previous edition with a discussion of the latest experimental and computational strategies used in the study, characterization, and targeting of enzymes with therapeutic potential. The chapters in the book are organized into two parts: Part One presents detailed, reproducible protocols for enzyme characterization, inhibitor screening, and biochemical ... Læs mere

    1.495,06 kr.