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Chromatin Immunoprecipitation

Methods and Protocols

Redigeret af Franziska Greulich ...

Serier serie Springer Protocols
This comprehensive guide delves into the protocols and strategies for investigating gene regulation both experimentally and computationally. It focuses on the use of Chromatin Immunoprecipitation (ChIP) coupled with next-generation sequencing, providing a robust framework for profiling DNA-binding proteins, examining DNA footprinting, and analyzing histone modifications. As part of the highly ... Læs mere

1.999,20 kr.

This comprehensive guide delves into the protocols and strategies for investigating gene regulation both experimentally and computationally. It focuses on the use of Chromatin Immunoprecipitation (ChIP) coupled with next-generation sequencing, providing a robust framework for profiling DNA-binding proteins, examining DNA footprinting, and analyzing histone modifications. As part of the highly
... Læs mere

Bioinformatics and Functional Genomics

af Jonathan Pevsner ...

The bestselling introduction to bioinformatics and genomics – now in its third editionWidely received in its previous editions, Bioinformatics and Functional Genomics offers the most broad-based introduction to this explosive new discipline. Now in a thoroughly updated and expanded third edition, it continues to be the go-to source for students and professionals involved in biomedical research ... Læs mere

1.035,61 kr.

The bestselling introduction to bioinformatics and genomics – now in its third editionWidely received in its previous editions, Bioinformatics and Functional Genomics offers the most broad-based introduction to this explosive new discipline. Now in a thoroughly updated and expanded third edition, it continues to be the go-to source for students and professionals involved in biomedical research
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Next Generation Sequencing and Sequence Assembly

Methodologies and Algorithms

af Ali Masoudi-Nejad, Zahra Narimani, Nazanin Hosseinkhan ...

Serier serie Biomedical and Life Sciences (R0)
The goal of this book is to introduce the biological and technical aspects of next generation sequencing methods, as well as algorithms to assemble these sequences into whole genomes. The book is organized into two parts; part 1 introduces NGS methods and part 2 reviews assembly algorithms and gives a good insight to these methods for readers new to the field. Gathering information, about ... Læs mere

466,97 kr.

The goal of this book is to introduce the biological and technical aspects of next generation sequencing methods, as well as algorithms to assemble these sequences into whole genomes. The book is organized into two parts; part 1 introduces NGS methods and part 2 reviews assembly algorithms and gives a good insight to these methods for readers new to the field. Gathering information, about
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Polymerase Chain Reactions

Basic Optimization Techniques

af Dr. M. MUTHURAJ, Dr. B. USHARANI, Dr. S. ANBAZHAGI, Dr. C.K. VIDYA RAJ, Dr. K. VENKATESH ...

This book describes how to perform and optimize the various types of Polymerase Chain Reactions (PCR) for postgraduate students, scholars and researchers in all branches of life science. PCR is a method widely used to rapidly make millions to billions of copies of specific DNA samples, allowing scientists to take a very small sample of DNA and amplify it (or a part of it) to a large enough amount ... Læs mere

20,81 kr.

This book describes how to perform and optimize the various types of Polymerase Chain Reactions (PCR) for postgraduate students, scholars and researchers in all branches of life science. PCR is a method widely used to rapidly make millions to billions of copies of specific DNA samples, allowing scientists to take a very small sample of DNA and amplify it (or a part of it) to a large enough amount
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Drosophila

Methods and Protocols

Redigeret af Christian Dahmann ...

Serier serie Springer Protocols
This third edition expands on the previous editions by providing updated protocols and current methods that cover recent breakthroughs in Drosophila research. Chapters guide readers through FlyBase, versatile gene expression systems, analysis of microRNA function, single-cell transcriptome data and metabolism, recent applications of CRISPR for precise genome editing, transcriptional activation and ... Læs mere

1.134,86 kr.

This third edition expands on the previous editions by providing updated protocols and current methods that cover recent breakthroughs in Drosophila research. Chapters guide readers through FlyBase, versatile gene expression systems, analysis of microRNA function, single-cell transcriptome data and metabolism, recent applications of CRISPR for precise genome editing, transcriptional activation and
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Synthetic Biology, 2 Volumes

Redigeret af Robert A. Meyers ...

Serier serie Advances in Molecular Biology and Medicine
These two volumes contain a selection of updated articles from the acclaimed Meyers Encyclopedia of Molecular Cell Biology and Molecular Medicine, the most authoritative resource in cell and molecular biology, combined with new articles by "founding fathers" in the field.The work is divided into six sections:+ Biological Basis+ Modeling+ Modular Parts and Circuits+ Synthetic Genomes+ Diseases and ... Læs mere

1.873,86 kr.

These two volumes contain a selection of updated articles from the acclaimed Meyers Encyclopedia of Molecular Cell Biology and Molecular Medicine, the most authoritative resource in cell and molecular biology, combined with new articles by "founding fathers" in the field.The work is divided into six sections:+ Biological Basis+ Modeling+ Modular Parts and Circuits+ Synthetic Genomes+ Diseases and
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Catharanthus roseus

Methods and Protocols

Redigeret af Vincent Courdavault, Sebastien Besseau ...

Serier serie Springer Protocols
This volume provides updated technical approaches that have been developed to characterize monoterpene indole alkaloid metabolism in C. roseus from metabolite/gene product localization, alkaloid chemical synthesis, candidate gene prediction, transcription factor characterization up to functional genomic tools based on gene overexpression. Written in the format of the highly successful Methods in ... Læs mere

1.868,14 kr.

This volume provides updated technical approaches that have been developed to characterize monoterpene indole alkaloid metabolism in C. roseus from metabolite/gene product localization, alkaloid chemical synthesis, candidate gene prediction, transcription factor characterization up to functional genomic tools based on gene overexpression. Written in the format of the highly successful Methods in
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Mass Spectrometry-Based Proteomics

Redigeret af Kris Gevaert ...

Serier serie Springer Protocols
This detailed volume explores contemporary techniques in mass spectrometry-based proteomics. After covering overall proteome coverage and the cellular surfaceome, the book delves into proximity-induced biotinylation, abduction of protein complexes in viral-like particles, and thermal proteome profiling, as well as protocols for identifying protein N-terminal acetylation, protein processing by ... Læs mere

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This detailed volume explores contemporary techniques in mass spectrometry-based proteomics. After covering overall proteome coverage and the cellular surfaceome, the book delves into proximity-induced biotinylation, abduction of protein complexes in viral-like particles, and thermal proteome profiling, as well as protocols for identifying protein N-terminal acetylation, protein processing by
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Spatial Genome Organization

Methods and Protocols

Redigeret af Tom Sexton ...

Serier serie Springer Protocols
This detailed volume explores a variety of cutting-edge techniques used to interrogate spatial genome organization. Beginning with a section covering the vital chromosome conformation capture (3C) technique, this collection continues with chapters on targeted Hi-C approaches, sequencing-based approaches to assess nuclear environment, as well as single-cell technologies to better characterize the ... Læs mere

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This detailed volume explores a variety of cutting-edge techniques used to interrogate spatial genome organization. Beginning with a section covering the vital chromosome conformation capture (3C) technique, this collection continues with chapters on targeted Hi-C approaches, sequencing-based approaches to assess nuclear environment, as well as single-cell technologies to better characterize the
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DNA-Protein Interactions

Methods and Protocols

Redigeret af Marcos Simoes-Costa ...

Serier serie Springer Protocols
This volume details protocols emphasizing systems-level approaches that can be applied to genomic analyses. Chapters detail techniques for optimized application in in vivo systems, spatial, physiological, environmental contexts, imaging-based techniques, single-molecule approaches, CRISPR systems, new genomic approaches, and measurements of kinetics governing. Written in the format of the highly ... Læs mere

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This volume details protocols emphasizing systems-level approaches that can be applied to genomic analyses. Chapters detail techniques for optimized application in in vivo systems, spatial, physiological, environmental contexts, imaging-based techniques, single-molecule approaches, CRISPR systems, new genomic approaches, and measurements of kinetics governing. Written in the format of the highly
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R-Loops

Methods and Protocols

Redigeret af Andrés Aguilera, Alexey Ruzov ...

Serier serie Springer Protocols
This detailed book compiles a series of laboratory protocols covering the most important aspects of R-loop biology. Beginning with a range of methods allowing for the detection of DNA-RNA hybrids, as well as their purification and visualization by electron microscopy, the volume continues with methods based on the use of RNase H-derived tools to detect DNA-RNA hybrids in vitro and in vivo. Several ... Læs mere

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This detailed book compiles a series of laboratory protocols covering the most important aspects of R-loop biology. Beginning with a range of methods allowing for the detection of DNA-RNA hybrids, as well as their purification and visualization by electron microscopy, the volume continues with methods based on the use of RNase H-derived tools to detect DNA-RNA hybrids in vitro and in vivo. Several
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Mitochondrial DNA

Methods and Protocols

Redigeret af Thomas J. Nicholls, Jay P. Uhler, Maria Falkenberg ...

Serier serie Springer Protocols
This volume compiles a comprehensive range of methods to study key aspects of mitochondrial DNA including nucleoid structure and packaging, replication, genome integrity, and disease. Chapters are organized into eight methodological sections that cover in vitro and in vivo methods, including for mtDNA isolation, visualization, deep sequencing, gene editing, and diagnostic aspects of mtDNA disease. ... Læs mere

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This volume compiles a comprehensive range of methods to study key aspects of mitochondrial DNA including nucleoid structure and packaging, replication, genome integrity, and disease. Chapters are organized into eight methodological sections that cover in vitro and in vivo methods, including for mtDNA isolation, visualization, deep sequencing, gene editing, and diagnostic aspects of mtDNA disease.
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Bioinformatics and Functional Genomics

Next Generation Sequencing and Sequence Assembly

Polymerase Chain Reactions

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Synthetic Biology, 2 Volumes

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Mass Spectrometry-Based Proteomics

Spatial Genome Organization

DNA-Protein Interactions

R-Loops

Mitochondrial DNA