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  • SH2 Domains

    Functional Modules and Evolving Tools in Biology

    Redigeret af Teresa Carlomagno, Maja Köhn ...
    Serier serie Springer Protocols
    This volume looks at the latest methods used to study and modulate the biological function and mechanisms of SH2 domains. The chapters in this book are organized into five parts. Part One presents methodology aimed at determining the structures and dynamics of SH2 domains and their complexes with phosphopeptides. Part Two discusses techniques to understand and predict interactions of SH2 domains ... Læs mere

    1.414,11 kr.

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  • Introducing Proteomics

    From Concepts to Sample Separation, Mass Spectrometry and Data Analysis

    af Josip Lovric ...
    Introducing Proteomics gives a concise and coherent overview of every aspect of current proteomics technology, which is a rapidly developing field that is having a major impact within the life and medical sciences.This student-friendly book, based on a successful course developed by the author, provides its readers with sufficient theoretical background to be able to plan, prepare, and analyze a ... Læs mere

    339,36 kr.

  • Protein Purification

    Principles, High Resolution Methods, and Applications

    Redigeret af Jan-Christer Janson ...
    Serier Bog 151 - Methods of Biochemical Analysis
    The authoritative guide on protein purification—now completely updated and revisedSince the Second Edition of Protein Purification was published in 1998, the sequencing of the human genome and other developments in bioscience have dramatically changed the landscape of protein research. This new edition addresses these developments, featuring a wealth of new topics and several chapters rewritten ... Læs mere

    1.182,36 kr.

  • Aggregation of Therapeutic Proteins

    Redigeret af Wei Wang, Christopher J. Roberts ...
    This book gives pharmaceutical scientists an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. While significant progress has been made in the past decade, the current understanding of protein aggregation and its consequences is still immature. Prevention or even moderate inhibition of protein aggregation has ... Læs mere

    1.001,49 kr.

  • Protein and Peptide Mass Spectrometry in Drug Discovery

    The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discoveryAn instrumental analytical method for quantifying the mass and characterization of various samples from small molecules to large proteins, mass spectrometry (MS) has become one of the most widely used techniques for studying proteins and peptides over the last decade. Bringing ... Læs mere

    1.202,36 kr.

  • Field-Flow Fractionation in Biopolymer Analysis

    Serier serie Chemistry and Material Science (R0)
    This is a timely collection of important biomedical applications for a set of separation/characterization techniques that are rapidly gaining popularity due to their wide dynamic range, high resolution, and ability to function in most commonly used solvent systems. Importantly, the field-flow fractionation (FFF) technique has recently emerged as a prominent complement to size exclusion ... Læs mere

    1.307,45 kr.

  • Biomolecular Forms And Functions: A Celebration Of 50 Years Of The Ramachandran Map

    Understanding the functions and properties of molecules in living systems requires a detailed knowledge of their three-dimensional structures and the conformational variability that allows them to adopt multiple functional forms. Interpreting biological systems in the language of three-dimensional structures is of fundamental importance and innumerable research groups around the world are working ... Læs mere

    438,61 kr.

  • Capillary Electrophoresis and Microchip Capillary Electrophoresis

    Principles, Applications, and Limitations

    Explores the benefits and limitations of the latest capillary electrophoresis techniquesCapillary electrophoresis and microchip capillary electrophoresis are powerful analytical tools that are particularly suited for separating and analyzing biomolecules. In comparison with traditional analytical techniques, capillary electrophoresis and microchip capillary electrophoresis offer the benefits of ... Læs mere

    1.061,99 kr.

  • Disruption of Protein-Protein Interfaces

    In Search of New Inhibitors

    Redigeret af Stefano Mangani ...
    Serier serie Chemistry and Material Science (R0)
    "Disruption of Protein-Protein Interfaces" reviews the latest developments and future perspectives in drug discovery at protein-protein interfaces. The authors detail experimental and computational tools to tackle the subject and highlight the contribution of the Italian research community to the field. Evidence shows that blocking or modulating protein-protein interactions might lead to the ... Læs mere

    756,49 kr.

  • Analytical Characterization of Biotherapeutics

    Redigeret af Jennie R. Lill, Wendy Sandoval ...
    The definitive guide to the myriad analytical techniques available to scientists involved in biotherapeutics researchAnalytical Characterization of Biotherapeutics covers all current and emerging analytical tools and techniques used for the characterization of therapeutic proteins and antigen reagents. From basic recombinant antigen and antibody characterization, to complex analyses for ... Læs mere

    1.216,49 kr.

  • Biophysics for Therapeutic Protein Development

    Redigeret af Linda O. Narhi ...
    Serier serie Biomedical and Life Sciences (R0)
    This book can be used to provide insight into this important application of biophysics for those who are planning a career in protein therapeutic development, and for those outside this area who are interested in understanding it better. The initial chapters describe the underlying theory, and strengths and weaknesses of the different techniques commonly used during therapeutic development. The ... Læs mere

    1.307,45 kr.

  • Protein Instability at Interfaces During Drug Product Development

    Fundamental Understanding, Evaluation, and Mitigation

    Serier serie Biomedical and Life Sciences (R0)
    Proteins are exposed to various interfacial stresses during drug product development. They are subjected to air-liquid, liquid-solid, and, sometimes, liquid-liquid interfaces throughout the development cycle-from manufacturing of drug substances to storage and drug delivery. Unlike small molecule drugs, proteins are typically unstable at interfaces where, on adsorption, they often denature and ... Læs mere

    756,49 kr.