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  • Translational Research Methods for Pediatric Brain Tumors

    Redigeret af Michael Goldstein ...
    Serier serie Springer Protocols
    This volume focuses on translational models of pediatric brain cancers that are critical to understanding tumor formation, tumor progression, and response to treatment. These models are particularly important for drug screens and preclinical testing of novel treatment approaches involving chemotherapy, radiation, and immunotherapy. The chapters in this book cover a variety of the latest ... Læs mere

    1.867,83 kr.

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  • Antibiotics and Bacterial Resistance

    af Wiley ...
    Serier serie Life Science Research Fundamentals
    The need for novel antibiotics is greater now than perhaps any time since the pre-antibiotic era. Indeed, the recent collapse of many pharmaceutical antibacterial groups, combined with the emergence of hypervirulent and pan-antibiotic-resistant bacteria has severely compromised infection treatment options and led to dramatic increases in the incidence and severity of bacterial infections.This ... Læs mere

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  • Interface Oral Health Science 2014

    Innovative Research on Biosis-Abiosis Intelligent Interface

    Serier serie Springer Nature Proceedings excluding Computer Science
    The Tohoku University Graduate School of Dentistry first introduced the concept of “Interface Oral Health Science”, designed to establish and maintain healthy oral cavities, which are home to a number of mixed systems. Included in those systems are: (1) host tissues such as teeth, mucosa, muscle and bone, (2) parasites and microorganisms cohabiting the surfaces of the oral cavity and (3) ... Læs mere

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  • BSL3 and BSL4 Agents

    Proteomics, Glycomics and Antigenicity

    Unique coverage of proteomic and glycomic approaches to better distinguish highly dangerous pathogens, as well as using these to explore novel treatment and prevention options.The editors and authors are either part of a specialized European network initiated to develop fast and reliable detection and therapy options, or are associated with the core military research complex of the United States ... Læs mere

    814,86 kr.

  • The Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis

    How stem cells behave is very much a factor of their local microenvironment, also known as the stem cell niche. Physical, chemical, or electrical signals from the neighboring cells or biochemical signals from distant cells are crucial in the cell fate decision process. A major challenge of tissue engineering is to mimic the natural cell environment by designing very sophisticated scaffolds able ... Læs mere

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  • Microfluidics and Multi Organs on Chip

    Redigeret af P. V. Mohanan ...
    Serier serie Biomedical and Life Sciences (R0)
    This book highlights the application of microfluidics in cell biology research, chemical biology, and drug discovery. It covers the recent breakthroughs and prospects of organ-on-a-chip, human-on-a-chip, multi-organ-on-a-chip for personalized medicine. The book presents the preclinical studies of organs-on-a-chip, concepts of multiple vascularized organ-on-chips, application of organ-on-a-chip in ... Læs mere

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  • Neuromuscular Assessments of Form and Function

    Serier serie Springer Protocols
    This volume looks at the latest methods used to study imaging techniques, metabolic tracing, and deep muscle phenotyping. The chapters in this book cover topics such as imaging skeletal muscle mass using MRI, dual-energy x-ray absorptiometry, CT, and ultrasound; measures of neuromuscular function such as power/strength/force; microscopy and immunohistochemistry; and ex vivo fibre function and ... Læs mere

    1.571,11 kr.

  • Applications of Mass Spectrometry in Microbiology

    From Strain Characterization to Rapid Screening for Antibiotic Resistance

    Redigeret af Plamen Demirev, Todd R. Sandrin ...
    Serier serie Chemistry and Material Science (R0)
    In the last quarter century, advances in mass spectrometry (MS) have been at the forefront of efforts to map complex biological systems including the human metabolome, proteome, and microbiome. All of these developments have allowed MS to become a well-established molecular level technology for microorganism characterization. MS has demonstrated its considerable advantage as a rapid, accurate, and ... Læs mere

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  • Tertiary Lymphoid Structures

    Methods and Protocols

    Redigeret af Marie-Caroline Dieu-Nosjean ...
    Serier serie Springer Protocols
    This second edition details new and updated chapters on technologies related to tertiary lymphoid structures( TLS). Chapters guide readers through TLS in cancers, different stages of TLS development, immune function of TLS, molecular, cellular, and imaging methods, and preclinical methods to uncover the function of cells composing TLS in inflammatory situations in humans. Written in the highly ... Læs mere

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  • Electromechanobiology of Cartilage and Osteoarthritis

    A Tribute to Alan Grodzinsky on his 75th Birthday

    Serier serie Biomedical and Life Sciences (R0)
    This is an open access book.In honor of his 75th birthday, we reflect on the impact of the pioneering work of Alan Grodzinsky and his laboratory.This volume includes in-depth discussions of tissue electromechanics, mechanobiology and biomechanics, and matrix biology in addition to the latest advancements in understanding the pathogenesis, progression and treatment of osteoarthritis. Unique to this ... Læs mere

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  • Blood-Brain Barrier

    Redigeret af Tatiana Barichello ...
    Serier serie Springer Protocols
    This volume details experimental research with applicable models to study physiology, biochemistry, and molecular biology of the blood-brain barrier (BBB). Chapters guide readers through the physiology of BBB, in vitro cell models to study the BBB, in vivo and ex vivo models to evaluate BBB, permeability, influx, efflux transportation, drug delivery through the BBB, invasive and non-invasive ... Læs mere

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  • Vectorology for Optogenetics and Chemogenetics

    Serier serie Springer Protocols
    This volume provides an overview of the viral vectors and how they are applied to chemogenetic and optogenetic tools to the study of neural circuits. The chapters in this book are organized into three parts detailing (1) viral vectors, (2) vector modifications and applications, and (3) practical advice for the delivery of viral vectors, verification of injection accuracy, and monitoring of ... Læs mere

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