In the second edition of this popular book, world famous numismatist Alan Herbert returns to answer 1,001 questions, from the routine to the exotic, from collectors, dealers, scholars and anyone curious about money. Drawing from his popular "Coin Clinic" column published in Numismatic News and Coins magazine, Herbert's answers are concise, informative - and always spot on!Whether a novice or an experienced collector, this fascinating book will save the reader from making e...

Alan Herbert has played a leading part in discovering the biological roles for a high-energy form of DNA twisted to the left rather than to the right. Both Z-DNA and the Z-RNA sensing proteins are critical for protecting hosts against both viruses and cancers. The proteins also play critical roles in the programmed cell death of aging cells. Other types of flipons exist and alter the readout of transcripts from the genome, encoding genetic information by their shape rather than by their se...

Best-selling guide for over 25 years and an essential companion for students taking biology courses, this 6 page laminated guide is a must-have for reference throughout science courses as a serious study tool and quick refresher for the core concepts, terms, diagrams, cycles and stages in the study of life. Author, scientist, and university biology professor Randy Brooks, PhD has streamlined the complicated subject of biology by selecting the need-to-know answers that will boost test score...

**Exploring the most transformative breakthroughs in biology since the discovery of the double helix, a Nobel Prize–winning scientist unveils the RNA age."Lively and entertaining.…Biology will never be the same." —Adrian Woolfson, Wall Street JournalAn Economist Best Book of the Year**For over half a century, DNA has dominated science and the popular imagination as the “secret of life.” But over the last several decades, a quiet revolution has take...

Drawn from the pages of Scientific American and collected here for the first time, this work contains updated and condensed information, made accessible to a general popular science audience, on the subject of understanding the genome.

After more than fifty years of blockbuster drug development, skeptics are beginning to fear we are reaching the end of drug discovery to combat major diseases. In this engaging book, Brent R. Stockwell, a leading researcher in the exciting new science of chemical biology, describes this dilemma and the powerful techniques that may bring drug research into the twenty-first century.Filled with absorbing stories of breakthroughs, this book begins with the scientific achievements of th...

What’s in Your Genome? describes the functional regions of the human genome, the evidence that 90% of it is junk DNA, and the reasons this evidence has not been widely accepted by the popular press and much of the scientific community.The human genome contains about 25,000 protein-coding and noncoding genes and many other functional elements, such as origins of replication, regulatory elements, and centromeres. Functional elements occupy only about 10 perc...

The origin story and emergence of molecular biology is muddled. The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate history. This book documents the many advances, as well as the prejudices and founder fallacies. It highlights the premature relegation of RNA to simply an intermediate between gene and protein, the underestimation of the amount of information required to program the development of multicellular organisms, and the da...

Seven million people die from cancer each year around the world, and many more are impacted by this universal scourge. In Betrayed by Nature, research scientist and lecturer Robin Hesketh demystifies the nature of cancer.Hesketh provides a concise and comprehensive history of both the science and the medical advances made over the decades. He takes the reader on a riveting tour of human biology; he explains how cancers start, what is meant by 'a mutation', and how mutations...

Many research studies have demonstrated that DNA hypermethylation is linked to the development of clear cell renal cell carcinomas (ccRCC) by the transcriptional silencing of important tumor suppressor genes known as Von Hippel-Lindau (VHL). The results of these studies led me to ask the question, “could hypomethylating agents be used to demethylate the hypermethylated H3K4me1 marks of VHL tumor suppressor genes to reactivate the transcriptional activity of these genes?”. This is the quest...

"This volume inspires. It certainly will be much appreciated by cell biologists all over the world."Quarterly Review of Biology, March 2009This book is the eagerly awaited second edition of the best-selling Mitochondria, a book widely acknowledged as the first modern, truly comprehensive authored work on the important, scientifically fundamental topic of the cellular organelles known as mitochondria.This new edition brings readers c...

The fourth edition of this popular textbook retains its focus on the fundamental principles of gene manipulation, providing an accessible and broad-based introduction to the subject for beginning undergraduate students. It has been brought thoroughly up to date with new chapters on the story of DNA and genome editing, and new sections on bioethics, significant developments in sequencing technology and structural, functional and comparative genomics and proteomics, and the impact of transge...