This book explores the application of formal methods, rooted in mathematics and logic, to the analysis and enhancement of biomedical ontologies. The authors take a pragmatic approach focused on generating actionable insights to achieve high-quality codified biomedical knowledge in the most active and impactful areas where ontologies have a direct real-world impact. The book first introduces simple, yet formalized strategies for discovering undesired and incoherent patterns in ontologies be...

The book synthesizes research on the analysis of biomedical ontologies using formal concept analysis, including through auditing, curation, and enhancement. As the evolution of biomedical ontologies almost inevitably involves manual work, formal methods are a particularly useful tool for ontological engineering and practice, particularly in uncovering unexpected "bugs" and content materials.The book first introduces simple but formalized strategies for discovering undesired and inc...

Markov ModelsThis book will offer you an insight into the Hidden Markov Models as well as the Bayesian Networks. Additionally, by reading this book, you will also learn algorithms such as Markov Chain Sampling.Furthermore, this book will also teach you how Markov Models are very relevant when a decision problem is associated with a risk that continues over time, when the timing of occurrenc...

This two-volume set LNCS 12962 and 12963 constitutes the thoroughly refereed proceedings of the 7th International MICCAI Brainlesion Workshop, BrainLes 2021, as well as the RSNA-ASNR-MICCAI Brain Tumor Segmentation (BraTS) Challenge, the Federated Tumor Segmentation (FeTS) Challenge, the Cross-Modality Domain Adaptation (CrossMoDA) Challenge, and the challenge on Quantification of Uncertainties in Biomedical Image Quantification (QUBIQ). These were held jointly at the 23rd Medical Image Co...

Principles of Biomedial Informatics provides a foundation for understanding the fundamentals of biomedical informatics, which deals with the storage, retrieval, and use of biomedical data for biological problem solving and medical decision making. It covers the application of these principles to the three main biomedical domains of basic biology, clinical medicine, and public health. The author offers a coherent summary, focusing on the three core concept areas of biomedical data and knowl...

The aims and scope of the second edition are unchanged from the first edition. The major market is in health informatics education. The three part format, which covers principles of health interoperability, HL7 and interchange formats, and SNOMED CT and clinical terminology, works well. In the US, The ONC (Office of the National Coordinator for Health Information Technology) has estimated that the HITECH stimulus will create more than 50,000 new jobs for health informatics professionals, w...

Since the construction of the first embedded system in the 1960s, embedded systems have continued to spread. They provide a continually increasing number of services and are part of our daily life. The development of these systems is a difficult problem which does not yet have a global solution. Another difficulty is that systems are plunged into the real world, which is not discrete (as is generally understood in computing), but has a richness of behaviors which sometimes hinders the form...

Statistical Shape and Deformation Analysis: Methods, Implementation and Applications contributes enormously to solving different problems in patient care and physical anthropology, ranging from improved automatic registration and segmentation in medical image computing to the study of genetics, evolution and comparative form in physical anthropology and biology. This book gives a clear description of the concepts, methods, algorithms and techniques developed over the last three decades tha...

This second edition of a pioneering technical work in biomedical informatics provides a very readable treatment of the deep computational ideas at the foundation of the field. Principles of Biomedical Informatics, 2nd Edition is radically reorganized to make it especially useable as a textbook for courses that move beyond the standard introductory material. It includes exercises at the end of each chapter, ideas for student projects, and a number of new topics, such as:• tree structured da...

This book will provide readers with the essential information needed to understand knowledge representation with a focus on healthcare. The book will use health sector real world examples to delineate the principal issues and solutions for the field of data representation. The book will include a history of terminologies and in particular their use in healthcare. This book will cover the basis, authoring and use of reference terminologies including the formalisms needed to use them safely....

Creating New Medical Ontologies for Image Annotation focuses on the problem of the medical images automatic annotation process, which is solved in an original manner by the authors. All the steps of this process are described in detail with algorithms, experiments and results. The original algorithms proposed by authors are compared with other efficient similar algorithms.In addition, the authors treat the problem of creating ontologies in an automatic way, starting from M...

This book describes the technical problems and solutions for automatically recognizing and parsing a medical image into multiple objects, structures, or anatomies. It gives all the key methods, including state-of- the-art approaches based on machine learning, for recognizing or detecting, parsing or segmenting, a cohort of anatomical structures from a medical image. Written by top experts in Medical Imaging, this book is ideal for university researchers and industry practitioners in medica...