This volume reviews key scientific principles and practices of passive antibody therapy for the treatment of infectious diseases. The main focus is on convalescent plasma, which is the most useful therapeutic option early in an epidemic, and may be especially important in low- and middle-income countries. The book’s first section reviews the history of passive antibody therapies prior to the COVID pandemic, while the second section assesses convalescent plasma use during the COVID pandemic...

The product of six years of collaborative research, this fine biography offers new interpretations of a pioneering figure in anesthesiology, epidemiology, medical cartography, and public health. It modifies the conventional rags to riches portrait of John Snow by synthesizing fresh information about his early life from archival research and recent studies. It explores the intellectual roots of his commitments to vegetarianism, temperance, and pure drinking water, first developed when he wa...

In 1831, an unknown, horrifying and deadly disease from Asia swept across Continental Europe, killing millions in its path and throwing the medical profession into confusion. Cholera is a killer with little respect for class or wealth. When it arrived in Britain, its repercussions rocked Victorian England - from the filthy lanes of the Sunderland quayside and the squalid streets of Soho, to the great centres of power: the Privy Council, Whitehall and the Royal Medical Colleges. One man - a...

Much as we take comfort in the belief that modern medicine and public health tactics can protect us from horrifying contagious diseases, such faith is dangerously unfounded. So demonstrates Mark Harrison in this pathbreaking investigation of the intimate connections between trade and disease throughout modern history. For centuries commerce has been the single most important factor in spreading diseases to different parts of the world, the author shows, and today the same is true. But in t...

This book is the principal account of epidemiology's role in the development of effective measures to identify, prevent, and treat diseases. Throughout history, epidemiologists have challenged conventional knowledge, elucidating mysteries of causality and paving the way for remedies. From the outbreak of the bubonic plague, cholera, and cancer to the search for an effective treatment of AIDS and the origins of Alzheimer's disease, epidemiological thought has been crucial in shaping our und...

Peter Piot, founding executive director of the Joint United Nations Programme on HIV/AIDS (UNAIDS), recounts his experience as a clinician, scientist, and activist fighting the disease from its earliest manifestation to today. The AIDS pandemic was not only catastrophic to the health of millions worldwide but also fractured international relations, global access to new technologies, and public health policies in nations across the globe. As he struggled to get ahead of the disease, Piot fo...

'A long-awaited book that answers many questions.' Jan de Vries Antibiotics were developed in the 1940s. Then, they were hailed as a huge breakthrough in the treatment of bacterial infections. Today, they are the most commonly prescribed drugs worldwide. But massive over-prescription of antibiotics has created its own problems. The advent of antibiotic-resistant organisms – or 'superbugs' – has led more and more people to demand alternatives. Natural Alternatives to Antibiotics is a revise...

This book traces the social and environmental determinants of human infectious diseases from the Neolithic to the present day. Despite recent high profile discoveries of new pathogens, the major determinants of these emerging infections are ancient and recurring. These include changing modes of subsistence, shifting populations, environmental disruptions, and social inequalities. The recent labeling of the term "re-emerging infections" reflects a re-emergence, not so much of the diseases t...

When plague broke out in Manchuria in 1910 as a result of transmission from marmots to humans, it struck a region struggling with the introduction of Western medicine, as well as with the interactions of three different national powers: Chinese, Japanese, and Russian. In this fascinating case history, William Summers relates how this plague killed as many as 60,000 people in less than a year, and uses the analysis to examine the actions and interactions of the multinational doctors, politi...

The press and other media constantly report news stories about dangerous chemicals in the environment, miracle cures, the safety of therapeutic treatments, and potential cancer-causing agents. But what exactly is actually meant by increased risk”-should we worry if we are told that we are at twice the risk of developing an illness? And how do we interpret reduced risk” to properly assess the benefits of noisily touted dietary supplements?   Demonstrating the diff...

Allergy truly is a modern malady. Only one hundred years ago, the term 'allergy' was unknown, and diseases subsequently identified as allergic in nature, such as asthma, hayfever, eczema and food intolerance, were routinely considered to be rare, non-fatal conditions primarily afflicting the cultured and civilized classes of Western society.By the closing decade of the twentieth century, however, allergy had acquired greater medical, political, socio-economic and cultural significan...

A History of Epidemics in Britain (Volume II of II) : From the Extinction of Plague to the Present TimeThis volume is the continuation of ‘A History of Epidemics in Britain from a.d. 664 to the Extinction of Plague’, and is the completion of the history to the present time. The two volumes may be referred to conveniently as the first and second of a ‘History of Epidemics in Britain.’ In adhering to the plan of a systematic history instead of annals I have encounter...