Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As ...

Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a c...

Ralph sat up. His voice was croaky. ‘If a shooting star zoomed past right now, what would you wish for?’ ‘To find another friend like you.’ Leo and Ralph have been best friends ever since Ralph flew down from one of Jupiter's moons. But now Leo's older, and Mum and Dad think it’s time to say goodbye to Ralph. When the family moves to a small country town, they hope Leo might finally make a real friend. But someone like Ralph is hard to leave behind ...

A dynamic remastering of the second BBC Radio 4 full-cast serial – Fit the Seventh to Fit the Twelfth – which spawned a phenomenal hitchhiking legendThe second original series of The Hitchhiker’s Guide to the Galaxy remastered by Dirk Maggs (director of the Tertiary, Quandary and Quintessential Phases) to give a full, vibrant sound, now with Philip Pope’s version of the familiar theme tune and specially re-recorded announcements by John Marsh.Stran...

Featuring stunning illustrations, this compact volume explores the early successes of the aircraft model and its aces.Although only built in modest numbers principally for the Dutch Air Force, the low-cost monoplane D.XXI fighter enjoyed its greatest success in combat with the Finnish Air Force. The Dutch D.XXIs saw less than a week of action following the German invasion of the west on 10 May 1940, with many of the country's 28 fighters being destroyed on the grou...

An illustrated history of a remarkable aircraft, the Dornier Do 24, which served both military and humanitarian purposes.Perhaps the most seaworthy flying boat ever built, the elegant, tri-motor Dornier Do 24 served with both the Allied and Axis forces in very different parts of the globe during World War 2, garnering an excellent reputation along the way. This study uses archival records, first-hand accounts and revealing photographs to illuminate the combat caree...

An illustrated history of a remarkable aircraft, the Dornier Do 24, which served both military and humanitarian purposes.Perhaps the most seaworthy flying boat ever built, the elegant, tri-motor Dornier Do 24 served with both the Allied and Axis forces in very different parts of the globe during World War 2, garnering an excellent reputation along the way. This study uses archival records, first-hand accounts and revealing photographs to illuminate the combat caree...

Featuring stunning illustrations, this compact volume explores the early successes of the aircraft model and its aces.Although only built in modest numbers principally for the Dutch Air Force, the low-cost monoplane D.XXI fighter enjoyed its greatest success in combat with the Finnish Air Force. The Dutch D.XXIs saw less than a week of action following the German invasion of the west on 10 May 1940, with many of the country's 28 fighters being destroyed on the grou...

One bright spring morning in the woods of France, a soldier, blinded by the war, is found by a little girl named Coco, and her older sister Marcelle. In return for their kindness, the soldier tells the sisters marvellous tales, each story connected to the keepsake he carries in his pocket: a perfect, tiny silver donkey. As the days pass and they struggle in secret to help the soldier reach home, Coco and Marcelle learn the truth behind the silver donkey, and what the precious object means:...

An instant classic with a bear-sized heart, Hannah Gold’s debut novel is a touching story of kindness,adventure, and forging your own path—perfect for fans of Pax and AWolf Called Wander.There are no polar bears left onBear Island. At least, that’s what April’s father tells her when his scientificresearch takes them to a faraway Arctic outpost.But one night, April catches aglimpse of something distinctly ...

Provides both fundamentals and new and emerging applicationsAdvanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatmen...

These are the proceedings of the third Asian Pacific Adalat Symposium. The first was held in Tokyo in 1982 and the second in Sydney in 1985. We were honoured that the late Dr. Sukaman and his colleagues were able to host this third symposium in Jakarta. This meeting was designed to contribute to and to promote international collaboration in cardiovascular research, and to help promote further knowledge and understanding about the treatment of vascular disease in the Asian Pacific area. Nif...